A novel subtype of primary prostatic adenocarcinoma: A case report

  • Authors:
    • Xiaoqing Yang
    • Chen Xu
    • Jianing Guo
    • Chunrui Yang
    • Yuming Yang
    • Ruifa Han
  • View Affiliations

  • Published online on: September 2, 2013     https://doi.org/10.3892/ol.2013.1557
  • Pages: 1303-1306
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Abstract

The present study reports the novel case of an 81‑year‑old male with prostatic adenocarcinoma (PAC), whose histopathological study revealed a pure urothelial carcinoma (UC) that originated, however, from the prostatic glandular epithelium. The levels of serum prostate‑specific antigen (PSA) were extraordinarily high in this patient. An MRI scan indicated a prostatic neoplasm and no malignant changes were observed in the bladder or other areas of the urinary tract. Hematoxylin and eosin‑stained sections revealed a diagnosis of pure UC with no other form of differentiation (typical adenocarcinoma or squamous differentiation). The immunohistochemical findings were positive for PSA and P504S, and negative for CK7, CK20, 34βE12 and p63. A diagnosis of primary PAC (solid carcinoma) originating from the prostate was made based on the clinical, histopathological and immunohistochemical observations. This case was susceptible to diagnostic errors, however, a novel subtype of primary PAC was identified and termed the UC‑like subtype.
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November 2013
Volume 6 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Yang X, Xu C, Guo J, Yang C, Yang Y and Han R: A novel subtype of primary prostatic adenocarcinoma: A case report. Oncol Lett 6: 1303-1306, 2013
APA
Yang, X., Xu, C., Guo, J., Yang, C., Yang, Y., & Han, R. (2013). A novel subtype of primary prostatic adenocarcinoma: A case report. Oncology Letters, 6, 1303-1306. https://doi.org/10.3892/ol.2013.1557
MLA
Yang, X., Xu, C., Guo, J., Yang, C., Yang, Y., Han, R."A novel subtype of primary prostatic adenocarcinoma: A case report". Oncology Letters 6.5 (2013): 1303-1306.
Chicago
Yang, X., Xu, C., Guo, J., Yang, C., Yang, Y., Han, R."A novel subtype of primary prostatic adenocarcinoma: A case report". Oncology Letters 6, no. 5 (2013): 1303-1306. https://doi.org/10.3892/ol.2013.1557