A novel subtype of primary prostatic adenocarcinoma: A case report

Yang,Xiaoqing; Xu,Chen; Guo,Jianing; Yang,Chunrui; Yang,Yuming; Han,Ruifa

doi:10.3892/ol.2013.1557

November 2013 Volume 6 Issue 5

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November 2013 Volume 6 Issue 5

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Case Report

A novel subtype of primary prostatic adenocarcinoma: A case report

Authors:
- Xiaoqing Yang
- Chen Xu
- Jianing Guo
- Chunrui Yang
- Yuming Yang
- Ruifa Han
View Affiliations / Copyright

Affiliations: Tianjin Institute of Urology, Department of Urology, Second Hospital of Tianjin Medical University, Hexi, Tianjin, P.R. China, Department of Colorectal Surgery, Affiliated Hospital of Nankai University, Hongqiao, Tianjin, P.R. China
Pages: 1303-1306
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Published online on: September 2, 2013

https://doi.org/10.3892/ol.2013.1557
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Abstract

The present study reports the novel case of an 81‑year‑old male with prostatic adenocarcinoma (PAC), whose histopathological study revealed a pure urothelial carcinoma (UC) that originated, however, from the prostatic glandular epithelium. The levels of serum prostate‑specific antigen (PSA) were extraordinarily high in this patient. An MRI scan indicated a prostatic neoplasm and no malignant changes were observed in the bladder or other areas of the urinary tract. Hematoxylin and eosin‑stained sections revealed a diagnosis of pure UC with no other form of differentiation (typical adenocarcinoma or squamous differentiation). The immunohistochemical findings were positive for PSA and P504S, and negative for CK7, CK20, 34βE12 and p63. A diagnosis of primary PAC (solid carcinoma) originating from the prostate was made based on the clinical, histopathological and immunohistochemical observations. This case was susceptible to diagnostic errors, however, a novel subtype of primary PAC was identified and termed the UC‑like subtype.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

A novel subtype of primary prostatic adenocarcinoma: A case report

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Abstract

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