Relapsing intracranial plasma cell granuloma: A case report

Renfrow,Jaclyn J.; Mitchell,Jerry W.; Goodman,Michael; Mellen,Leigh A.; Wilson,John A.; Mott,Ryan T.; Lesser,Glenn J.

doi:10.3892/ol.2013.1722

2014-February Volume 7 Issue 2

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2014-February Volume 7 Issue 2

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Case Report

Relapsing intracranial plasma cell granuloma: A case report

Authors:
- Jaclyn J. Renfrow
- Jerry W. Mitchell
- Michael Goodman
- Leigh A. Mellen
- John A. Wilson
- Ryan T. Mott
- Glenn J. Lesser
View Affiliations / Copyright

Affiliations: Wake Forest University School of Medicine, Winston‑Salem, NC 27157, USA, The Mark H. Zangmeister Center, Columbus, OH 43219, USA, Department of Internal Medicine, Section on Hematology and Oncology, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston‑Salem, NC 27157, USA, Hattiesburg Clinic, Department of Pathology, Hattiesburg, MS 39401, USA, Department of Neurosurgery, Wake Forest University School of Medicine, Winston‑Salem, NC 27157, USA, Department of Pathology, Wake Forest University School of Medicine, Winston‑Salem, NC 27157, USA
Pages: 531-533
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Published online on: December 2, 2013

https://doi.org/10.3892/ol.2013.1722
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Abstract

Plasma cell granuloma is a pathological entity reported in nearly every organ system; however, intracranial cases remain rare. In the current case report, we present a case of intracranial plasma cell granuloma with the longest known follow‑up period in the literature. Medical follow‑up over 14 years, detailing four recurrences following the patient's initial presentation and management, is presented. The patient's treatment course consisted of three craniotomies, 3,600‑cGy fractionated radiation and two courses of glucocorticoid therapy. In addition to disease surveillance using clinical examination and imaging, this case represents the first description of the clinical utility of analyzing changes in an inflammatory blood marker, the erythrocyte sedimentation rate, which coincided with recurrence and response to therapy.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Relapsing intracranial plasma cell granuloma: A case report

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Abstract

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