Severe aplastic anemia preceding acute monocytic leukemia in an adult with acquired trisomy 21: A case report

  • Authors:
    • Dongmei Guo
    • Qinqin Liu
    • Banban Li
    • Qingliang Teng
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  • Published online on: December 3, 2013     https://doi.org/10.3892/ol.2013.1724
  • Pages: 565-567
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Abstract

The current case report presents a patient with acute monocytic leukemia (AML‑M5) occurring 14 years following the successful treatment of severe aplastic anemia (SAA) with immunosuppressants and androgens. The patient was treated with induction chemotherapy, but did not achieve remission. The patient succumbed to central nervous system bleeding 2 weeks following the first cycle of chemotherapy. Chromosomal examination revealed 47,XX,+21[10]/46,XX[1]. To the best of our knowledge the present case is the first to be reported of SAA 14 years preceding AML‑M5 with acquired trisomy 21.
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2014-February
Volume 7 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Guo D, Liu Q, Li B and Teng Q: Severe aplastic anemia preceding acute monocytic leukemia in an adult with acquired trisomy 21: A case report. Oncol Lett 7: 565-567, 2014
APA
Guo, D., Liu, Q., Li, B., & Teng, Q. (2014). Severe aplastic anemia preceding acute monocytic leukemia in an adult with acquired trisomy 21: A case report. Oncology Letters, 7, 565-567. https://doi.org/10.3892/ol.2013.1724
MLA
Guo, D., Liu, Q., Li, B., Teng, Q."Severe aplastic anemia preceding acute monocytic leukemia in an adult with acquired trisomy 21: A case report". Oncology Letters 7.2 (2014): 565-567.
Chicago
Guo, D., Liu, Q., Li, B., Teng, Q."Severe aplastic anemia preceding acute monocytic leukemia in an adult with acquired trisomy 21: A case report". Oncology Letters 7, no. 2 (2014): 565-567. https://doi.org/10.3892/ol.2013.1724