|
1
|
Parsons DW, Jones S, Zhang X, et al: An
integrated genomic analysis of human glioblastoma multiforme.
Science. 321:1807–1812. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Herman JG and Baylin SB: Gene silencing in
cancer in association with promoter hypermethylation. N Engl J Med.
349:2042–2054. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Karpf AR and Matsui S: Genetic disruption
of cytosine DNA methyltransferase enzymes induces chromosomal
instability in human cancer cells. Cancer Res. 65:8635–8639. 2005.
View Article : Google Scholar
|
|
4
|
Bello MJ and Rey JA: The p53/Mdm2/p14ARF
cell cycle control pathway genes may be inactivated by genetic and
epigenetic mechanisms in gliomas. Cancer Genet Cytogenet.
164:172–173. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Gibbs S, Fijneman R, Wiegant J, van Kessel
AG, van De Putte P and Backendorf C: Molecular characterization and
evolution of the SPRR family of keratinocyte differentiation
markers encoding small proline-rich proteins. Genomics. 16:630–637.
1993. View Article : Google Scholar
|
|
6
|
Steinert PM, Candi E, Kartasova T and
Marekov L: Small proline-rich proteins are cross-bridging proteins
in the cornified cell envelopes of stratified squamous epithelia. J
Struct Biol. 122:76–85. 1998. View Article : Google Scholar
|
|
7
|
Zhang Y, Feng YB, Shen XM, et al:
Exogenous expression of Esophagin/SPRR3 attenuates the
tumorigenicity of esophageal squamous cell carcinoma cells via
promoting apoptosis. Int J Cancer. 122:260–266. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Tesfaigzi J, Th’ng J, Hotchkiss JA,
Harkema JR and Wright PS: A small proline-rich protein, SPRR1, is
upregulated early during tobacco smoke-induced squamous metaplasia
in rat nasal epithelia. Am J Respir Cell Mol Biol. 14:478–486.
1996. View Article : Google Scholar
|
|
9
|
Fischer DF, Sark MW, Lehtola MM, Gibbs S,
van de Putte P and Backendorf C: Structure and evolution of the
human SPRR3 gene: implications for function and regulation.
Genomics. 55:88–99. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Cabral A, Sayin A, de Winter S, Fischer
DF, Pavel S and Backendorf C: SPRR4, a novel cornified envelope
precursor: UV-dependent epidermal expression and selective
incorporation into fragile envelopes. J Cell Sci. 114:3837–3843.
2001.
|
|
11
|
Abraham JM, Wang S, Suzuki H, et al:
Esophagin cDNA cloning and characterization: a tissue-specific
member of the small proline-rich protein family that is not
expressed in esophageal tumors. Cell Growth Differ. 7:855–860.
1996.
|
|
12
|
Chen BS, Wang MR, Cai Y, et al: Decreased
expression of SPRR3 in Chinese human oesophageal cancer.
Carcinogenesis. 21:2147–2150. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Cho DH, Jo YK, Roh SA, et al: Upregulation
of SPRR3 promotes colorectal tumorigenesis. Mol Med. 16:271–277.
2010.PubMed/NCBI
|
|
14
|
Kim JC, Yu JH, Cho YK, et al: Expression
of SPRR3 is associated with tumor cell proliferation in less
advanced stages of breast cancer. Breast Cancer Res Treat.
133:909–916. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hill VK, Ricketts C, Bieche I, et al:
Genome-wide DNA methylation profiling of CpG islands in breast
cancer identifies novel genes associated with tumorigenicity.
Cancer Res. 71:2988–2999. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wen PY and Kesari S: Malignant gliomas in
adults. N Engl J Med. 359:492–507. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Nagarajan RP and Costello JF: Epigenetic
mechanisms in glioblastoma multiforme. Semin Cancer Biol.
19:188–197. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Fanelli M, Caprodossi S, Ricci-Vitiani L,
et al: Loss of pericentromeric DNA methylation pattern in human
glioblastoma is associated with altered DNA methyltransferases
expression and involves the stem cell compartment. Oncogene.
27:358–365. 2008. View Article : Google Scholar
|
|
19
|
Kim TY, Zhong S, Fields CR, Kim JH and
Robertson KD: Epigenomic profiling reveals novel and frequent
targets of aberrant DNA methylation-mediated silencing in malignant
glioma. Cancer Res. 66:7490–7501. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Foltz G, Ryu GY, Yoon JG, et al:
Genome-wide analysis of epigenetic silencing identifies BEX1 and
BEX2 as candidate tumor suppressor genes in malignant glioma.
Cancer Res. 66:6665–6674. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cadieux B, Ching TT, VandenBerg SR and
Costello JF: Genome-wide hypomethylation in human glioblastomas
associated with specific copy number alteration,
methylenetetrahydrofolate reductase allele status, and increased
proliferation. Cancer Res. 66:8469–8476. 2006. View Article : Google Scholar
|
|
22
|
Yu J, Zhang H, Gu J, et al: Methylation
profiles of thirty four promoter-CpG islands and concordant
methylation behaviours of sixteen genes that may contribute to
carcinogenesis of astrocytoma. BMC Cancer. 14:652004. View Article : Google Scholar
|
|
23
|
Uhlmann K, Rohde K, Zeller C, et al:
Distinct methylation profiles of glioma subtypes. Int J Cancer.
106:52–59. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Costello JF, Frühwald MC, Smiraglia DJ, et
al: Aberrant CpG-island methylation has non-random and
tumour-type-specific patterns. Nat Genet. 24:132–138. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ammerpohl O, Pratschke J, Schafmayer C, et
al: Distinct DNA methylation patterns in cirrhotic liver and
hepatocellular carcinoma. Int J Cancer. 130:1319–1328. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mayol G, Martín-Subero JI, Ríos J, et al:
DNA hypomethylation affects cancer-related biological functions and
genes relevant in neuroblastoma pathogenesis. PLoS One.
7:e484012012. View Article : Google Scholar
|
|
27
|
Fritz V and Fajas L: Metabolism and
proliferation share common regulatory pathways in cancer cells.
Oncogene. 29:4369–4377. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Davis CD, Emenaker NJ and Milner JA:
Cellular proliferation, apoptosis and angiogenesis: molecular
targets for nutritional preemption of cancer. Semin Oncol.
37:243–257. 2010. View Article : Google Scholar
|
|
29
|
Weinstein IB and Joe A: Oncogene
addiction. Cancer Res. 68:3077–3080. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
McCubrey JA, Steelman LS, Abrams SL, et
al: Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in
malignant transformation and drug resistance. Adv Enzyme Regul.
46:249–279. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Testa JR and Bellacosa A: AKT plays a
central role in tumorigenesis. Proc Natl Acad Sci USA.
98:10983–10985. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Protzel C, Knoedel J, Zimmermann U,
Woenckhaus C, Poetsch M and Giebel J: Expression of proliferation
marker Ki67 correlates to occurrence of metastasis and prognosis,
histological subtypes and HPV DNA detection in penile carcinomas.
Histol Histopathol. 22:1197–1204. 2007.
|
|
33
|
Yamashita Y, Kasugai I, Sato M, et al:
CDC25A mRNA levels significantly correlate with Ki-67 expression in
human glioma samples. J Neurooncol. 100:43–49. 2010. View Article : Google Scholar
|
