L‑asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature

  • Authors:
    • Fang Wu
    • Lu Qu
    • Yafen Tan
    • Yue Zhang
    • Chunhong Hu
  • View Affiliations

  • Published online on: February 11, 2014     https://doi.org/10.3892/ol.2014.1871
  • Pages: 1305-1307
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Abstract

L‑asparaginase (L‑Asp)‑associated pancreatitis (AAP) occurs occasionally; however, this side‑effect has predominantly been observed among pediatric patients. Usually, it is not life‑threatening and generally responds to intensive medical therapy. The present study presents a rare case of lethal AAP in an adult. The patient was recently diagnosed with extranodal natural killer/T‑cell lymphoma (ENKTL), nasal type, and the chronic hepatitis B virus (HBV) infection and was receiving L‑Asp as part of a chemotherapy regimen. Severe acute pancreatitis occurred and the patient succumbed 72 h after completion of chemotherapy. The HBV infection and lipid disorders may have been potential risk factors for the development of severe acute pancreatitis in the patient.
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2014-April
Volume 7 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Wu F, Qu L, Tan Y, Zhang Y and Hu C: L‑asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature. Oncol Lett 7: 1305-1307, 2014
APA
Wu, F., Qu, L., Tan, Y., Zhang, Y., & Hu, C. (2014). L‑asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature. Oncology Letters, 7, 1305-1307. https://doi.org/10.3892/ol.2014.1871
MLA
Wu, F., Qu, L., Tan, Y., Zhang, Y., Hu, C."L‑asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature". Oncology Letters 7.4 (2014): 1305-1307.
Chicago
Wu, F., Qu, L., Tan, Y., Zhang, Y., Hu, C."L‑asparaginase-induced severe acute pancreatitis in an adult with extranodal natural killer/T-cell lymphoma, nasal type: A case report and review of the literature". Oncology Letters 7, no. 4 (2014): 1305-1307. https://doi.org/10.3892/ol.2014.1871