Role of FDG-PET/CT for monitoring soft tissue tumors

  • Authors:
    • Manabu Hoshi
    • Naoto Oebisu
    • Jun Takada
    • Makoto Ieguchi
    • Kenichi Wakasa
    • Hiroaki Nakamura
  • View Affiliations

  • Published online on: February 12, 2014     https://doi.org/10.3892/ol.2014.1876
  • Pages: 1243-1248
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Abstract

The aim of the current study was to evaluate the limitations of 2‑deoxy‑2‑F18‑fluoro‑D‑glucose positron emission tomography combined with computed tomography (FDG‑PET/CT) when monitoring soft tissue tumors. The diagnostic criteria of malignancy was defined as the tumor having a maximum standardized uptake value (SUVmax) ≥2.0 and a maximum diameter ≥5 cm as measured using FDG‑PET/CT. One-hundred-and-thirteen patients, that were either included in the criteria or not, were compared. In addition, the values of SUVmax of the primary tumor and relapse in 12 patients were evaluated. The Kaplan‑Meier analysis demonstrated that patients with tumors measuring ≥5 cm size and ≥2.0 SUVmax were associated with a worse survival rate. Among the 12 patients with relapse, statistical significances were detected in the tumor diameters, however, not in the SUVmax values. Thus, the criteria identified patients that were associated with a poor prognosis, and the SUVmax of distant metastases and local recurrences were identified to be significantly affected by tumor size.
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2014-April
Volume 7 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Hoshi M, Oebisu N, Takada J, Ieguchi M, Wakasa K and Nakamura H: Role of FDG-PET/CT for monitoring soft tissue tumors. Oncol Lett 7: 1243-1248, 2014
APA
Hoshi, M., Oebisu, N., Takada, J., Ieguchi, M., Wakasa, K., & Nakamura, H. (2014). Role of FDG-PET/CT for monitoring soft tissue tumors. Oncology Letters, 7, 1243-1248. https://doi.org/10.3892/ol.2014.1876
MLA
Hoshi, M., Oebisu, N., Takada, J., Ieguchi, M., Wakasa, K., Nakamura, H."Role of FDG-PET/CT for monitoring soft tissue tumors". Oncology Letters 7.4 (2014): 1243-1248.
Chicago
Hoshi, M., Oebisu, N., Takada, J., Ieguchi, M., Wakasa, K., Nakamura, H."Role of FDG-PET/CT for monitoring soft tissue tumors". Oncology Letters 7, no. 4 (2014): 1243-1248. https://doi.org/10.3892/ol.2014.1876