Postoperative spindle cell nodule of the bladder: A case report and review of the literature

Zhao,Jiyu; Ping,Hao; Xing,Nianzeng

doi:10.3892/ol.2014.1927

May-2014 Volume 7 Issue 5

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

May-2014 Volume 7 Issue 5

Full Size Image

Case Report

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

Authors:
- Jiyu Zhao
- Hao Ping
- Nianzeng Xing
View Affiliations / Copyright

Affiliations: Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China
Pages: 1507-1510
|
Published online on: February 28, 2014

https://doi.org/10.3892/ol.2014.1927
Expand metrics +

Abstract

Postoperative spindle cell nodule (PSCN) of the bladder is a rare condition. It is a type of benign lesion frequently misdiagnosed as sarcomatoid carcinoma on the basis of similar cell morphology. The present report describes a tumor affecting a 71‑year‑old male who had undergone three transurethral resections. Pathological results suggested a diagnosis of sarcomatoid carcinoma, and therefore a radical cystectomy was performed. However, the tumor was later identified as a PSCN. In order to prevent such misdiagnosis, this study reviews relevant articles concerning postoperative spindle cell nodules of the bladder and compares PSCN and sarcomatoid carcinomas to identify specific characteristics of PSCN. Finally, the report emphasizes the importance of careful pathological examination in rare cases such as PSCN and sarcomatoid carcinoma.

View Figures

View References

1	Huang WL, Ro JY, Grignon DJ, Swanson D, Ordonez NG and Ayala AG: Postoperative spindle cell nodule of the prostate and bladder. J Urol. 143:824–826. 1990.PubMed/NCBI
2	Young RH: Tumor-like lesions of the urinary bladder. Mod Pathol. 22(Suppl 2): S37–S52. 2009. View Article : Google Scholar : PubMed/NCBI
3	Proppe KH, Scully RE and Rosai J: Postoperative spindle cell nodules of genitourinary tract resembling sarcomas. A report of eight cases. Am J Surg Pathol. 8:101–108. 1984. View Article : Google Scholar
4	Kim SW, Oh YL, Choi JY, Lee JI, Chung JH and Kim JS: Postoperative spindle cell nodule after thyroidectomy: a case mimicking recurrence with anaplastic transformation of thyroid cancer. Head Neck. 35:E13–E17. 2013. View Article : Google Scholar
5	Montgomery EA, Shuster DD, Burkart AL, Esteban JM, Sgrignoli A, Elwood L, Vaughn DJ, Griffin CA and Epstein JI: Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma. Am J Surg Pathol. 30:1502–1512. 2006. View Article : Google Scholar
6	Lott S, Lopez-Beltran A, MacLennan GT, Montironi R and Cheng L: Soft tissue tumors of the urinary bladder, part I: myofibroblastic proliferations, benign neoplasms, and tumors of uncertain malignant potential. Hum Pathol. 38:807–823. 2007. View Article : Google Scholar
7	Micci F, Haugom L, Abeler VM, Bjerkehagen B and Heim S: Trisomy 7 in postoperative spindle cell nodules. Cancer Genet Cytogenet. 174:147–150. 2007. View Article : Google Scholar : PubMed/NCBI
8	Shanks JH and Iczkowski KA: Spindle cell lesions of the bladder and urinary tract. Histopathology. 55:491–504. 2009. View Article : Google Scholar : PubMed/NCBI
9	Eyden B: Electron microscopy in the study of myofibroblastic lesions. Semin Diagn Pathol. 20:13–24. 2003.PubMed/NCBI
10	Iczkowski KA, Shanks JH, Gadaleanu V, Cheng L, Jones EC, Neumann R, Nascimento AG and Bostwick DG: Inflammatory pseudotumor and sarcoma of urinary bladder: differential diagnosis and outcome in thirty-eight spindle cell neoplasms. Mod Pathol. 14:1043–1051. 2001. View Article : Google Scholar
11	Spiess PE, Tuziak T, Tibbs RF, Bassett R, Tamboli P, Brown GA, Grossman HB, Ayala AG and Czerniak B: Pseudosarcomatous and sarcomatous proliferations of the bladder. Hum Pathol. 38:753–761. 2007. View Article : Google Scholar
12	Lo JW, Fung CH, Yonan T and DiMauro J: Postoperative spindle-cell nodule of urinary bladder with unusual intracytoplasmic inclusions. Diagn Cytopathol. 8:171–176. 1992. View Article : Google Scholar : PubMed/NCBI
13	Wick MR, Brown BA, Young RH and Mills SE: Spindle-cell proliferations of the urinary tract. An immunohistochemical study. Am J Surg Pathol. 12:379–389. 1988. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Postoperative spindle cell nodule of the bladder: A case report and review of the literature

This article is mentioned in:

Abstract

Figure 1

Figure 2

Related Articles