CyberKnife radiotherapy for malignant fibrous histiocytoma of the chest wall: A case report and review of the literature

  • Authors:
    • Zhen Wang
    • Xin‑Hu Wu
    • Bing Li
    • Qing‑Tao Kong
    • Ze‑Tian Shen
    • Jing Li
    • Zhi‑Bing Liu
    • Xi‑Xu Zhu
  • View Affiliations

  • Published online on: March 24, 2014     https://doi.org/10.3892/ol.2014.1995
  • Pages: 1877-1880
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Abstract

Malignant fibrous histiocytoma (MFH) is the most common type of soft tissue sarcoma, but rarely originates in the chest wall. Surgical resection is considered to be the most reliable treatment, however, no consensus has been reached concerning the best treatment for unresectable MFH. The current study presents the case of a 77‑year‑old male with MFH of the chest wall. The patient developed a painless mass and intermittent fever over a four‑month period. A computed tomography scan demonstrated a large inhomogeneous lesion in the right chest wall, which was subsequently diagnosed via biopsy as a MFH. Since the tumor was an unresectable mass, CyberKnife® radiotherapy was conducted. Following the treatment, a marked reduction in the tumor size was observed with a tolerable level of toxicity. The sequencing analysis also revealed an in‑frame deletion (delE746‑A750) in exon 19 of the epidermal growth factor receptor gene. Based on this result, gefitinib was administered to the patient at a dose of 250 mg/day.
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June-2014
Volume 7 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Wang Z, Wu XH, Li B, Kong QT, Shen ZT, Li J, Liu ZB and Zhu XX: CyberKnife radiotherapy for malignant fibrous histiocytoma of the chest wall: A case report and review of the literature. Oncol Lett 7: 1877-1880, 2014
APA
Wang, Z., Wu, X., Li, B., Kong, Q., Shen, Z., Li, J. ... Zhu, X. (2014). CyberKnife radiotherapy for malignant fibrous histiocytoma of the chest wall: A case report and review of the literature. Oncology Letters, 7, 1877-1880. https://doi.org/10.3892/ol.2014.1995
MLA
Wang, Z., Wu, X., Li, B., Kong, Q., Shen, Z., Li, J., Liu, Z., Zhu, X."CyberKnife radiotherapy for malignant fibrous histiocytoma of the chest wall: A case report and review of the literature". Oncology Letters 7.6 (2014): 1877-1880.
Chicago
Wang, Z., Wu, X., Li, B., Kong, Q., Shen, Z., Li, J., Liu, Z., Zhu, X."CyberKnife radiotherapy for malignant fibrous histiocytoma of the chest wall: A case report and review of the literature". Oncology Letters 7, no. 6 (2014): 1877-1880. https://doi.org/10.3892/ol.2014.1995