Misdiagnosed gastrinoma: A case report

Sun,Qi‑Kai; Wang,Wei; Zhou,Hang‑Cheng; Lv,Yang; Yu,Ji‑Hai; Ma,Jin‑Liang; Jia,Wei‑Dong; Xu,Ge‑Liang

doi:10.3892/ol.2014.2019

June-2014 Volume 7 Issue 6

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June-2014 Volume 7 Issue 6

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Case Report

Misdiagnosed gastrinoma: A case report

Authors:
- Qi‑Kai Sun
- Wei Wang
- Hang‑Cheng Zhou
- Yang Lv
- Ji‑Hai Yu
- Jin‑Liang Ma
- Wei‑Dong Jia
- Ge‑Liang Xu
View Affiliations / Copyright

Affiliations: Department of General Surgery, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui 230001, P.R. China, Department of Medical Oncology, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui 230001, P.R. China, Department of Pathology, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui 230001, P.R. China
Pages: 2089-2092
|
Published online on: April 1, 2014

https://doi.org/10.3892/ol.2014.2019
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Abstract

Gastrinoma is most commonly located in the gastrinoma triangle (comprising of the duodenum, pancreas and bile ducts) or in the adjacent lymph nodes. Due to the low mortality rate, it is often misdiagnosed as other diseases with similar clinical characteristics, such as a solid pseudopapillary tumor of the pancreas (SPTP). Therefore, the current study reports a rare case of gastrinoma located in the tail of the pancreas of a female patient under medical examination, who exhibited no clinical symptoms. The tumor, which was located in the body and tail of the pancreas, was successfully resected and the spleen was preserved. The outcome of surgery combined with the postoperative pathological examination resulted in the patient being misdiagnosed with a SPTP. During the consequent six‑year follow‑up period, low‑density liver lesions and an intractable peptic ulcer gradually appeared. Finally, the patient diagnosis was confirmed as a malignant pancreatic neuroendocrine carcinoma with liver metastases. On June 1, 2011, a liver transplant was successfully performed and the patient has maintained a good overall condition. The underlying clinical and pathological factors that may have resulted in misdiagnosis are investigated in the present study. Through providing our preliminary clinical experiences and lessons, the aim of the present study was to focus the attention of clinicians on this type of cancer in order to improve its diagnosis and treatment.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Misdiagnosed gastrinoma: A case report

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