Pilomatrix carcinoma of the scalp with pulmonary metastasis: A case report of a complete response to oral endoxan and etoposide

Arslan,Deniz; Gündüz,Şeyda; Avci,Fatma; Merdin,Alparslan; Tatli,Ali Murat; Uysal,Mükremin; Tural,Deniz; Başsorgun,Cumhur İbrahim; Savaş,Burhan

doi:10.3892/ol.2014.2021

June-2014 Volume 7 Issue 6

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June-2014 Volume 7 Issue 6

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Case Report

Pilomatrix carcinoma of the scalp with pulmonary metastasis: A case report of a complete response to oral endoxan and etoposide

Authors:
- Deniz Arslan
- Şeyda Gündüz
- Fatma Avci
- Alparslan Merdin
- Ali Murat Tatli
- Mükremin Uysal
- Deniz Tural
- Cumhur İbrahim Başsorgun
- Burhan Savaş
View Affiliations / Copyright

Affiliations: Department of Medical Oncology, Akdeniz University Hospital, Konyaalti, Antalya, Turkey, Department of Internal Medicine, Akdeniz University Hospital, Konyaalti, Antalya, Turkey, Department of Medical Oncology, Afyon Kocatepe University, Ahmet Necdet Sezer Research and Practice Hospital, Afyon, Turkey, Department of Pathology, Akdeniz University Hospital, Konyaalti, Antalya, Turkey
Pages: 1959-1961
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Published online on: April 1, 2014

https://doi.org/10.3892/ol.2014.2021
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Abstract

Pilomatrix carcinoma is an extremely rare skin tumor derived from basaloid cells in the hair follicles; it often exhibits locally aggressive behavior with a tendency toward local recurrence. The average age of occurrence is 45 years, and there appears to be a male to female incidence ratio of 4:1. Although pilomatrix carcinomas are predominantly identified in the neck and scalp, there are studies in the literature reporting other tumor development sites, including the upper extremities, torso and popliteal fossa. If diagnosed at an early stage, this malignant tumor is generally treated with wide surgical resection. However, for the advanced‑stage tumors, there are no standard treatment procedures known to produce good results. The current study presents the case of a 76‑year‑old male with pilomatrix carcinoma originating from the scalp with metastases to the lung. The patient had a rapid and complete clinical response following an oral combination chemotherapy regimen of cyclophosphamide and etoposide.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Pilomatrix carcinoma of the scalp with pulmonary metastasis: A case report of a complete response to oral endoxan and etoposide

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