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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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July-2014 Volume 8 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review

  • Authors:
    • Liping Tong
    • Yong Wang
    • Yongan Zhou
    • Xiaoqing Zheng
    • Honggang Liu
    • Jianyong Sun
    • Xiaofei Li
    • Xiaolong Yan
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China, Department of General Surgery, Weinan Center Hospital, Weinan, Shaanxi 714000, P.R. China
  • Pages: 72-76
    |
    Published online on: April 15, 2014
       https://doi.org/10.3892/ol.2014.2069
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Abstract

Malignant fibrous histiocytoma (MFH) is rare in the chest wall, particularly in patients who have undergone radiotherapy for primary nasopharyngeal cancer. In the present study, a case of MFH of the upper chest wall that appeared four years after initial radiotherapy for squamous cell carcinoma of the nasopharynx is reported. Furthermore, two‑step surgical management was successfully performed consisting of i) tumor‑reductive excision and ii) limb salvage surgery, including wide resection of the tumor mass, defect reconstruction of the chest wall using left latissimus dorsi myocutaneous flap and dermatoplasty of the flap‑supplied region. The progress of the clinical characteristics, the reasons for radiation‑induced carcinogenesis, the treatment options and the prognostic factors of MFH are also reviewed. Finally, the importance of prevention and follow‑up of this malignancy are highlighted and specific advice is offered.
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Copy and paste a formatted citation
Spandidos Publications style
Tong L, Wang Y, Zhou Y, Zheng X, Liu H, Sun J, Li X and Yan X: Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review. Oncol Lett 8: 72-76, 2014.
APA
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J. ... Yan, X. (2014). Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review. Oncology Letters, 8, 72-76. https://doi.org/10.3892/ol.2014.2069
MLA
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J., Li, X., Yan, X."Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review". Oncology Letters 8.1 (2014): 72-76.
Chicago
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J., Li, X., Yan, X."Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review". Oncology Letters 8, no. 1 (2014): 72-76. https://doi.org/10.3892/ol.2014.2069
Copy and paste a formatted citation
x
Spandidos Publications style
Tong L, Wang Y, Zhou Y, Zheng X, Liu H, Sun J, Li X and Yan X: Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review. Oncol Lett 8: 72-76, 2014.
APA
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J. ... Yan, X. (2014). Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review. Oncology Letters, 8, 72-76. https://doi.org/10.3892/ol.2014.2069
MLA
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J., Li, X., Yan, X."Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review". Oncology Letters 8.1 (2014): 72-76.
Chicago
Tong, L., Wang, Y., Zhou, Y., Zheng, X., Liu, H., Sun, J., Li, X., Yan, X."Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review". Oncology Letters 8, no. 1 (2014): 72-76. https://doi.org/10.3892/ol.2014.2069
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