Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: A case report

Sun,Zhenzhong; Wang,Heng; Yang,Huilin; Jiang,Weimin

doi:10.3892/ol.2014.2132

July-2014 Volume 8 Issue 1

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July-2014 Volume 8 Issue 1

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Case Report

Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: A case report

Authors:
- Zhenzhong Sun
- Heng Wang
- Huilin Yang
- Weimin Jiang
View Affiliations / Copyright

Affiliations: Department of Orthopedics, Wuxi No. 9 People's Hospital, Wuxi, Jiangsu 214062, P.R. China, Department of Orthopedics, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China
Pages: 263-265
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Published online on: May 12, 2014

https://doi.org/10.3892/ol.2014.2132
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Abstract

Leiomyosarcoma is a rare malignant tumor derived from smooth muscle cells, which commonly metastasizes to the lungs, liver, kidney, brain and skin. The current study presents the case of a 42‑year‑old male who presented with progressive neck pain and numbness of the left arm. Spinal computed tomography and magnetic resonance imaging revealed osteolytic lesions of numerous vertebrae (C2, C3, C4, C5, C6, C7, T1 and T2). With regard to the C6 vertebra, total destruction of the vertebral body resulted in vertebral collapse and subsequent spinal cord compression. The patient underwent an anterior C6 corpectomy, reconstruction with a mesh cage filled with polymethyl methacrylate (PMMA) and open PMMA infusion to C5 and C7. The surgical procedure significantly alleviated the symptoms and obtained a reliable reconstruction. The clinical follow‑up examination at 13 months was uneventful with the exception of mild numbness of the left hand since the surgery. To the best of our knowledge, this is the first case of leiomyosarcoma recurrence presenting in the cervical spine, and the present study provides insight into the use of a surgical technique that has rarely been used in the cervical spine.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Leiomyosarcoma metastatic to the cervical spine causing a C6 compression fracture: A case report

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Abstract

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