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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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August-2014 Volume 8 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

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Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Article

High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients

  • Authors:
    • Yan Sun
    • Lin Wang
    • Sheng‑Chao Guo
    • Xiao-Bing Wu
    • Xue‑Hu Xu

  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, P.R. China, Department of Oncology, Guangzhou Red Cross Hospital, Guangzhou, Guangdong 510150, P.R. China, Department of General Surgery, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, P.R. China
  • Pages: 711-713
    |
    Published online on: June 3, 2014
       https://doi.org/10.3892/ol.2014.2215
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Abstract

The altered expression of microRNAs (miRNAs) is associated with a number of cancer types. The study of the association between the miRNA profile and cancer may be useful to identify potential biomarkers of certain types of cancer. In the present study, 19 miRNAs were identified by high‑throughput sequencing in the serum of colorectal cancer (CRC) patients. A network analysis was performed based on a computational approach to identify associations between CRC and miRNAs. The present study may be useful to identify cancer‑specific signatures and potentially useful biomarkers for the diagnosis of CRC. The network analysis of miRNA‑target genes may aid in identifying altered miRNA regulatory networks that are involved in tumor pathogenesis.
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Copy and paste a formatted citation
Spandidos Publications style
Sun Y, Wang L, Guo SC, Wu X and Xu XH: High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients. Oncol Lett 8: 711-713, 2014.
APA
Sun, Y., Wang, L., Guo, S., Wu, X., & Xu, X. (2014). High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients. Oncology Letters, 8, 711-713. https://doi.org/10.3892/ol.2014.2215
MLA
Sun, Y., Wang, L., Guo, S., Wu, X., Xu, X."High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients". Oncology Letters 8.2 (2014): 711-713.
Chicago
Sun, Y., Wang, L., Guo, S., Wu, X., Xu, X."High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients". Oncology Letters 8, no. 2 (2014): 711-713. https://doi.org/10.3892/ol.2014.2215
Copy and paste a formatted citation
x
Spandidos Publications style
Sun Y, Wang L, Guo SC, Wu X and Xu XH: High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients. Oncol Lett 8: 711-713, 2014.
APA
Sun, Y., Wang, L., Guo, S., Wu, X., & Xu, X. (2014). High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients. Oncology Letters, 8, 711-713. https://doi.org/10.3892/ol.2014.2215
MLA
Sun, Y., Wang, L., Guo, S., Wu, X., Xu, X."High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients". Oncology Letters 8.2 (2014): 711-713.
Chicago
Sun, Y., Wang, L., Guo, S., Wu, X., Xu, X."High‑throughput sequencing to identify miRNA biomarkers in colorectal cancer patients". Oncology Letters 8, no. 2 (2014): 711-713. https://doi.org/10.3892/ol.2014.2215
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