Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
September-2014 Volume 8 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September-2014 Volume 8 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Meningeal myofibroblastoma in the frontal lobe: A case report

  • Authors:
    • Qingsheng Xu
    • Yiping Feng
    • Pan Wu
    • Yongqing Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, P.R. China
  • Pages: 1291-1294
    |
    Published online on: June 26, 2014
       https://doi.org/10.3892/ol.2014.2290
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Myofibroblastoma is a benign tumor composed of spindle cells in clusters and fascicles. To date, only three cases of intracranial myofibroblastoma have been reported. The present study reports the case of a 47‑year‑old female with meningeal myofibroblastoma. The patient had a history of ovarian cyst resection and presented with paroxysmal mild headaches that had been apparent for 4 years. Magnetic resonance imaging disclosed a well‑circumscribed mass in the left frontal lobe. A resection of the mass was performed. Abundant fascicular clusters of spindle‑ and oval‑shaped cells were found by conventional histopathology. Immunohistochemical staining demonstrated that these cells were strongly positive for smooth muscle actin, weakly positive for epithelial membrane antigen and negative for cluster of differentiation (CD)117, CD34, S‑100 or desmin, with a Ki‑67 index of >10%. These results supported the diagnosis of myofibroblastoma. No recurrence of the mass was found during the 24‑month follow‑up period. Overall, the patient exhibited a rare type of meningeal neoplasm. Resection of the tumor proved to be successful and no recurrence were found. Histopathological and immunohistochemical staining is crucial to form a diagnosis. To the best of our knowledge, the present study is the first to show the presence of myofibroblastoma in the left frontal lobe.
View Figures

Figure 1

Figure 2

View References

1 

Powari M, Srinivasan R and Radotra BD: Myofibroblastoma of the male breast: a diagnostic problem on fine-needle aspiration cytology. Diagn Cytopathol. 26:290–293. 2002.

2 

Salomão DR, Crotty TB and Nascimento AG: Myofibroblastoma and solitary fibrous tumour of the breast: histopathologic and immunohistochemical studies. Breast. 10:49–54. 2001.

3 

Alguacil-Garcia A: Intranodal myofibroblastoma in a submandibular lymph node. A case report. Am J Clin Pathol. 97:69–72. 1992.

4 

Meister P, Wöckel W, Schmidt D and Trupka A: Pulmonary myofibroblastic nodules with “amianthoid features”. Pathol Res Pract. 187:906–911. 1991.

5 

Herrera GA, Johnson WW, Lockard VG and Walker BL: Soft tissue myofibroblastomas. Mod Pathol. 4:571–577. 1991.

6 

Sahin AA, Ro JY, Ordoñez NG, et al: Myofibroblastoma of the tongue. An immunohistochemical, ultrastructural, and flow cytometric study. Am J Clin Pathol. 94:773–777. 1990.

7 

Carneiro F, Gonçalves V and Simões MS: Myofibroblastoma of the meninges. Ultrastruct Pathol. 13:599–605. 1989.

8 

Prayson RA, Estes ML, McMahon JT, Kalfas I and Sebek BA: Meningeal myofibroblastoma. Am J Surg Pathol. 17:931–936. 1993.

9 

Shinojima N, Ohta K, Yano S, et al: Myofibroblastoma in the suprasellar region. Case report. J Neurosurg. 97:1203–1207. 2002.

10 

Laskin WB, Fetsch JF and Tavassoli FA: Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract. Hum Pathol. 32:715–725. 2001.

11 

Sotoudeh H and Yazdi HR: A review on dural tail sign. World J Radiol. 2:188–192. 2010.

12 

Suzuki SO, Fukui M, Nishio S and Iwaki T: Clinicopathological features of solitary fibrous tumor of the meninges: An immunohistochemical reappraisal of cases previously diagnosed to be fibrous meningioma or hemangiopericytoma. Pathol Int. 50:808–817. 2000.

13 

Yilmaz C, Kabatas S, Ozen OI, et al: Solitary fibrous tumor. J Clin Neurosci. 16:1578–1581. 2009.

14 

Martorell M, Pérez-Vallés A, Gozalbo F, et al: Solitary fibrous tumor of the thigh with epithelioid features: a case report. Diagn Pathol. 2:192007.

15 

Prayson RA, McMahon JT and Barnett GH: Solitary fibrous tumor of the meninges. Case report and review of the literature. J Neurosurg. 86:1049–1052. 1997.

16 

Song Z, Yu C, Song X, Wei L and Liu A: Primary solitary fibrous tumor of the thyroid - report of a case and review of the literature. J Cancer. 2:206–209. 2011.

17 

Tihan T, Viglione M, Rosenblum MK, Olivi A and Burger PC: Solitary fibrous tumors in the central nervous system. A clinicopathologic review of 18 cases and comparison to meningeal hemangiopericytomas. Arch Pathol Lab Med. 127:432–439. 2003.

18 

Carneiro SS, Scheithauer BW, Nascimento AG, Hirose T and Davis DH: Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. A clinicopathologic and immunohistochemical study. Am J Clin Pathol. 106:217–224. 1996.

19 

Perry A, Scheithauer BW and Nascimento AG: The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. Am J Surg Pathol. 21:1354–1360. 1997.

20 

Alén JF, Lobato RD, Gómez PA, et al: Intracranial hemangiopericytoma: study of 12 cases. Acta Neurochir (Wien). 143:575–586. 2001.

21 

Winek RR, Scheithauer BW and Wick MR: Meningioma, meningeal hemangiopericytoma (angioblastic meningioma), peripheral hemangiopericytoma, and acoustic schwannoma. A comparative immunohistochemical study. Am J Surg Pathol. 13:251–261. 1989.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Xu Q, Feng Y, Wu P and Zhou Y: Meningeal myofibroblastoma in the frontal lobe: A case report. Oncol Lett 8: 1291-1294, 2014.
APA
Xu, Q., Feng, Y., Wu, P., & Zhou, Y. (2014). Meningeal myofibroblastoma in the frontal lobe: A case report. Oncology Letters, 8, 1291-1294. https://doi.org/10.3892/ol.2014.2290
MLA
Xu, Q., Feng, Y., Wu, P., Zhou, Y."Meningeal myofibroblastoma in the frontal lobe: A case report". Oncology Letters 8.3 (2014): 1291-1294.
Chicago
Xu, Q., Feng, Y., Wu, P., Zhou, Y."Meningeal myofibroblastoma in the frontal lobe: A case report". Oncology Letters 8, no. 3 (2014): 1291-1294. https://doi.org/10.3892/ol.2014.2290
Copy and paste a formatted citation
x
Spandidos Publications style
Xu Q, Feng Y, Wu P and Zhou Y: Meningeal myofibroblastoma in the frontal lobe: A case report. Oncol Lett 8: 1291-1294, 2014.
APA
Xu, Q., Feng, Y., Wu, P., & Zhou, Y. (2014). Meningeal myofibroblastoma in the frontal lobe: A case report. Oncology Letters, 8, 1291-1294. https://doi.org/10.3892/ol.2014.2290
MLA
Xu, Q., Feng, Y., Wu, P., Zhou, Y."Meningeal myofibroblastoma in the frontal lobe: A case report". Oncology Letters 8.3 (2014): 1291-1294.
Chicago
Xu, Q., Feng, Y., Wu, P., Zhou, Y."Meningeal myofibroblastoma in the frontal lobe: A case report". Oncology Letters 8, no. 3 (2014): 1291-1294. https://doi.org/10.3892/ol.2014.2290
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team