|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011.
|
|
2
|
El-Serag HB, Marrero JA, Rudolph L and
Reddy KR: Diagnosis and treatment of hepatocellular carcinoma.
Gastroenterology. 134:1752–1763. 2008.
|
|
3
|
Thomas M: Molecular targeted therapy for
hepatocellular carcinoma. J Gastroenterol. 44(Suppl 19): S136–S141.
2009.
|
|
4
|
Malumbres M and Barbacid M: Cell cycle
kinases in cancer. Curr Opin Genet Dev. 17:60–65. 2007.
|
|
5
|
Sherr CJ: Cancer cell cycles. Science.
274:1672–1677. 1996.
|
|
6
|
Hanahan D and Weinberg RA: The hallmarks
of cancer. Cell. 100:57–70. 2000.
|
|
7
|
Fry AM and Nigg EA: Characterization of
mammalian NIMA-related kinases. Methods Enzymol. 283:270–282.
1997.
|
|
8
|
Quarmby LM and Mahjoub MR: Caught Nek-ing:
cilia and centrioles. J Cell Sci. 118:5161–5169. 2005.
|
|
9
|
O’Regan L, Blot J and Fry AM: Mitotic
regulation by NIMA-related kinases. Cell Div. 2:252007.
|
|
10
|
Wu L, Osmani SA and Mirabito PM: A role
for NIMA in the nuclear localization of cyclin B in Aspergillus
nidulans. J Cell Biol. 141:1575–1587. 1998.
|
|
11
|
Chen J, Li L, Zhang Y, et al: Interaction
of Pin1 with Nek6 and characterization of their expression
correlation in Chinese hepatocellular carcinoma patients. Biochem
Biophys Res Commun. 341:1059–1065. 2006.
|
|
12
|
Capra M, Nuciforo PG, Confalonieri S, et
al: Frequent alterations in the expression of serine/threonine
kinases in human cancers. Cancer Res. 66:8147–8154. 2006.
|
|
13
|
Polci R, Peng A, Chen PL, Riley DJ and
Chen Y: NIMA-related protein kinase 1 is involved early in the
ionizing radiation-induced DNA damage response. Cancer Res.
64:8800–8803. 2004.
|
|
14
|
Faragher AJ and Fry AM: Nek2A kinase
stimulates centrosome disjunction and is required for formation of
bipolar mitotic spindles. Mol Biol Cell. 14:2876–2889. 2003.
|
|
15
|
Lou Y, Yao J, Zereshki A, et al: NEK2A
interacts with MAD1 and possibly functions as a novel integrator of
the spindle checkpoint signaling. J Biol Chem. 279:20049–20057.
2004.
|
|
16
|
Melixetian M, Klein DK, Sørensen CS and
Helin K: NEK11 regulates CDC25A degradation and the IR-induced G2/M
checkpoint. Nat Cell Biol. 11:1247–1253. 2009.
|
|
17
|
Moniz LS and Stambolic V: Nek10 mediates
G2/M cell cycle arrest and MEK autoactivation in response to UV
irradiation. Mol Cell Biol. 31:30–42. 2011.
|
|
18
|
Kokuryo T, Yamamoto T, Oda K, et al:
Profiling of gene expression associated with hepatolithiasis by
complementary DNA expression array. Int J Oncol. 22:175–179.
2003.
|
|
19
|
Tsunoda N, Kokuryo T, Oda K, et al: Nek2
as a novel molecular target for the treatment of breast carcinoma.
Cancer Sci. 100:111–116. 2009.
|
|
20
|
Bowers AJ and Boylan JF: Nek8, a NIMA
family kinase member, is overexpressed in primary human breast
tumors. Gene. 328:135–142. 2004.
|
|
21
|
Ahmed S, Thomas G, Ghoussaini M, et al:
Newly discovered breast cancer susceptibility loci on 3p24 and
17q23.2. Nat Genet. 41:585–590. 2009.
|
|
22
|
Hernández M and Almeida TA: Is there any
association between nek3 and cancers with frequent 13q14 deletion?
Cancer Invest. 24:682–688. 2006.
|
|
23
|
Cao X, Xia Y, Yang J, et al: Clinical and
biological significance of never in mitosis gene A-related kinase 6
(NEK6) expression in hepatic cell cancer. Pathol Oncol Res.
18:201–207. 2012.
|
|
24
|
Jee HJ, Kim HJ, Kim AJ, Song N, Kim M and
Yun J: Nek6 suppresses the premature senescence of human cancer
cells induced by camptothecin and doxorubicin treatment. Biochem
Biophys Res. 408:669–673. 2011.
|
|
25
|
Jeon YJ, Lee KY, Cho YY, et al: Role of
NEK6 in tumor promoter-induced transformation in JB6 C141 mouse
skin epidermal cells. J Biol Chem. 285:28126–28133. 2010.
|
|
26
|
Nassirpour R, Shao L, Flanagan P, et al:
Nek6 mediates human cancer cell transformation and is a potential
cancer therapeutic target. Mol Cancer Res. 8:717–728. 2010.
|
