Systematic 12‑ and 13‑core transrectal ultrasound‑ or magnetic resonance imaging‑guided biopsies significantly improve prostate cancer detection rate: A single‑center 13‑year experience

Cheng,Gong; Huang,Yuan; Liu,Bianjiang; Zhao,Ruizhe; Shao,Pengfei; Li,Jie; Qin,Chao; Hua,Lixin; Yin,Changjun

doi:10.3892/ol.2014.2353

October 2014 Volume 8 Issue 4

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October 2014 Volume 8 Issue 4

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Article

Systematic 12‑ and 13‑core transrectal ultrasound‑ or magnetic resonance imaging‑guided biopsies significantly improve prostate cancer detection rate: A single‑center 13‑year experience

Authors:
- Gong Cheng
- Yuan Huang
- Bianjiang Liu
- Ruizhe Zhao
- Pengfei Shao
- Jie Li
- Chao Qin
- Lixin Hua
- Changjun Yin
View Affiliations / Copyright

Affiliations: Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China
Pages: 1834-1838
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Published online on: July 15, 2014

https://doi.org/10.3892/ol.2014.2353
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Abstract

The aim of the present study was to evaluate the value of systematic 12‑ and 13‑core biopsies, guided by transrectal ultrasound (TRUS) or magnetic resonance imaging (MRI), with regard to the prostate cancer detection rate (PCDR). Between July 1999 and June 2012, 2,707 patients were recruited to the Department of Urology, The First Affiliated Hospital of Nanjing Medical University (Nanjing, China). Prostate biopsies were performed via systematic 12‑ or 13‑core biopsy and guided by either TRUS or MRI. The PCDR was established by retrospectively analyzing the distribution of positive cores, and it was assumed that all patients had undergone four biopsy schemes: Medial 6‑core, lateral 6‑core, 12‑core and entire 13‑core. In addition, the positive rate of the biopsies with the extra 13th core and the mean positive rate of systematic 12‑core biopsies were compared. The PCDR of an entire 13‑core biopsy was significantly higher than that of a lateral 6‑core biopsy. The positive rate of the extra 13th core, which identified abnormal TRUS or MRI findings, was significantly higher when compared with that of the mean positive rate of the systematic 12‑core biopsy. The results of the present study demonstrated that the entire 13‑core biopsy was superior to the 6‑core biopsy with regard to the PCDR. Therefore, the systematic 12‑core biopsy with an extra 13th core is considered to be beneficial towards improving the PCDR.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Systematic 12‑ and 13‑core transrectal ultrasound‑ or magnetic resonance imaging‑guided biopsies significantly improve prostate cancer detection rate: A single‑center 13‑year experience

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