Magnetic resonance imaging of intracranial hemangiopericytoma and correlation with pathological findings

Ma,Cong; Xu,Feng; Xiao,Yu-Dong; Paudel,Ramchandra; Sun,Yi; Xiao,En-Hua

doi:10.3892/ol.2014.2503

November-2014 Volume 8 Issue 5

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November-2014 Volume 8 Issue 5

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Article

Magnetic resonance imaging of intracranial hemangiopericytoma and correlation with pathological findings

Authors:
- Cong Ma
- Feng Xu
- Yu-Dong Xiao
- Ramchandra Paudel
- Yi Sun
- En-Hua Xiao
View Affiliations / Copyright

Affiliations: Department of Radiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China, Yinzhou People's Hospital, Ningbo, Zhejiang 315000, P.R. China, Department of Pathology, The Second XiangYa Hospital of Central South University, Changsha, Hunan 410011, P.R. China
Pages: 2140-2144
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Published online on: September 4, 2014

https://doi.org/10.3892/ol.2014.2503
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Abstract

The present study aimed to evaluate the radiological and pathological features of intracranial hemangiopericytoma, and improve the understanding of this tumor. A retrospective analysis of radiological and pathological features of five cases of intracranial hemangiopericytoma was conducted between 2006 and 2012 in the Second Xiangya Hospital of Central South University. A total of five cases (three males and two females; aged 37‑60 years) were enrolled. Magnetic resonance imaging revealed that the lesions were lobulated with iso‑intensity T1‑weighted image signals and slightly long T2‑weighted image signals. Cystic degeneration, necrosis and flow void were observed. The case with the lesion located under the tentorium cerebelli exhibited compression of the fourth ventricle with lateral ventricle dilatation hydrocephalus. In all cases, the solid section of the lesion was markedly enhanced following injection of the contrast agent, and intratumoral vessels were observed. No case exhibited the dural tail sign. Immunohistochemical examination revealed positive expression of cluster of differentiation 34(CD34), vimentin and CD99, and negative expression of epithelial membrane antigen, S100 and glial fibrillary acidic protein. Proliferating cell nuclear antigen Ki‑67 immunohistochemical staining revealed that <5% of cells expressed Ki‑67 in two cases and 5‑10% of cells expressed Ki‑67 in three cases. In conclusion, intracranial hemangiopericytoma exhibits certain distinctive characteristics in radiological examination, allowing for improved diagnosis. However, pathological examination is required for confirmation.

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1	Rutkowski MJ, Jian BJ, Bloch O, et al: Intracranial hemangiopericytoma: clinical experience and treatment considerations in a modern series of 40 adult patients. Cancer. 118:1628–1636. 2012.
2	Holland H, Livrea M, Ahnert P, et al: Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis. Pathol Res Pract. 207:310–316. 2011.
3	Kleihues P and Cavenee WK: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Nervous System. IARC Press; Lyon: 2000
4	Fountas KN, Kapsalaki E, Kassam M, et al: Management of intracranial meningeal hemangiopericytoma: outcome and experience. Neurosurg Rev. 29:145–153. 2006.
5	Olson C, Yen CP, Schlesinger D and Sheehan J: Radiosurgery for intracranial hemangiopericytoma: outcomes after initial and repeat Gamma Knife surgery. J Neurosurg. 112:133–139. 2010.
6	Hori E, Kurimoto M, Fukuda O, et al: Recurrent intracranial solitary fibrous tumor initially diagnosed as hemangiopericytoma. Brain Tumor Pathol. 24:31–34. 2007.
7	Kumar R and Wani AA: Unusual tumors of the posterior fossa skull base. Skull Base. 16:75–84. 2006.
8	Stout AP and Murray MR: Hemangiopericytoma: a vascular tumor featuring Zimmerman’s pericytes. Ann Surg. 116:26–33. 1942.
9	Brunori A, Delitala A, Oddi G and Chiappetta F: Recent experience in the management of meningeal hemangiopericytomas. Tumori. 83:856–861. 1997.
10	Schiariti M, Goetz P, El-Maghraby H, Tailor J and Kitchen N: Hemangiopericytoma: long-term outcome revisited clinical article. J Neurosurg. 114:747–755. 2011.
11	Zhou JL, Liu JL, Zhang J and Zhang M: Thirty-nine cases of intracranial hemangiopericytoma and anaplastic hemangiopericytoma: A retrospective review of MRI features and pathological findings. Eur J Radiol. 81:3504–3510. 2012.
12	Wu W, Shi JX, Cheng HL, et al: Hemangiopericytomas in the central nervous system. J Clin Neurosci. 16:519–523. 2009.
13	Alén JF, Lobato RD, Gómez PA, et al: Intracranial Hemangiopericytoma: Study of 12 Cases. ACTA Neurochir. 143:575–586. 2001.
14	Shetty PM, Moiyadi AV and Sridhar E: Primary CNS hemangiopericytoma presenting as an intraparenchymal mass - case report and review of literature. Clin Neurol Neurosurg. 112:261–264. 2010.
15	Spatola C and Privitera G: Recurrent intracranial hemangiopericytoma with extracranial and unusual multiple metastases: case report and review of the literature. Tumori. 90:265–268. 2004.
16	Bonde VR and Goel A: Two patients with intracavernous hemangiopericytoma. J Clin Neurosci. 16:330–333. 2009.
17	Kumar N, Kumar R, Kapoor R, et al: Intracranial meningeal hemangiopericytoma: 10 years experience of a tertiary care institute. ACTA Neusrochir. 154:1647–1651. 2012.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Magnetic resonance imaging of intracranial hemangiopericytoma and correlation with pathological findings

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