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Article Open Access

Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery

  • Authors:
    • Yang Lin
    • Benzhong Wang
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China, Department of Breast Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China
  • Pages: 9-14
    |
    Published online on: November 12, 2014
       https://doi.org/10.3892/ol.2014.2704
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Abstract

The aim of this study was to investigate the dosimetric benefits between intensity‑modulated radiotherapy (IMRT) and conventional radiotherapy (CR) among patients receiving breast‑conserving surgery. A dosimetric comparison of IMRT and CR was evaluated in 20 patients with early‑stage breast cancer using a three‑dimensional treatment planning system. The prescribed mammary gland dose was completed in 25 fractions with a total dose of 5,000 cGy. Homogeneity of the planning target volume (PTV), irradiation dose and volume of organs at risk (OARs) were evaluated through a dose‑volume histogram. For the homogeneity of PTV, the average volume receiving 95% of the prescribed dose in the IMRT plan was similar to that in the CR plan (97 vs. 96%, respectively). With regard to normal tissue sparing in OARs, the ipsilateral lung V20 in the IMRT and CR plans was 27.8 and 20.8%, respectively. The mean dose and V30 of the heart for five patients were 598.4 versus 348.3 cGy and 10.06 versus 5.3%, respectively. The mean dose sparing the heart or lung was markedly reduced in the IMRT plan compared with the CR plan. The results of the current study demonstrated that whole breast IMRT improves PTV dose distribution and improves normal tissue sparing in OARs.
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Copy and paste a formatted citation
Spandidos Publications style
Lin Y and Wang B: Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncol Lett 9: 9-14, 2015.
APA
Lin, Y., & Wang, B. (2015). Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncology Letters, 9, 9-14. https://doi.org/10.3892/ol.2014.2704
MLA
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9.1 (2015): 9-14.
Chicago
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9, no. 1 (2015): 9-14. https://doi.org/10.3892/ol.2014.2704
Copy and paste a formatted citation
x
Spandidos Publications style
Lin Y and Wang B: Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncol Lett 9: 9-14, 2015.
APA
Lin, Y., & Wang, B. (2015). Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncology Letters, 9, 9-14. https://doi.org/10.3892/ol.2014.2704
MLA
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9.1 (2015): 9-14.
Chicago
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9, no. 1 (2015): 9-14. https://doi.org/10.3892/ol.2014.2704
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