Open Access

Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery

  • Authors:
    • Yang Lin
    • Benzhong Wang
  • View Affiliations

  • Published online on: November 12, 2014     https://doi.org/10.3892/ol.2014.2704
  • Pages: 9-14
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The aim of this study was to investigate the dosimetric benefits between intensity‑modulated radiotherapy (IMRT) and conventional radiotherapy (CR) among patients receiving breast‑conserving surgery. A dosimetric comparison of IMRT and CR was evaluated in 20 patients with early‑stage breast cancer using a three‑dimensional treatment planning system. The prescribed mammary gland dose was completed in 25 fractions with a total dose of 5,000 cGy. Homogeneity of the planning target volume (PTV), irradiation dose and volume of organs at risk (OARs) were evaluated through a dose‑volume histogram. For the homogeneity of PTV, the average volume receiving 95% of the prescribed dose in the IMRT plan was similar to that in the CR plan (97 vs. 96%, respectively). With regard to normal tissue sparing in OARs, the ipsilateral lung V20 in the IMRT and CR plans was 27.8 and 20.8%, respectively. The mean dose and V30 of the heart for five patients were 598.4 versus 348.3 cGy and 10.06 versus 5.3%, respectively. The mean dose sparing the heart or lung was markedly reduced in the IMRT plan compared with the CR plan. The results of the current study demonstrated that whole breast IMRT improves PTV dose distribution and improves normal tissue sparing in OARs.
View Figures
View References

Related Articles

Journal Cover

January-2015
Volume 9 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Lin Y and Lin Y: Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncol Lett 9: 9-14, 2015
APA
Lin, Y., & Lin, Y. (2015). Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery . Oncology Letters, 9, 9-14. https://doi.org/10.3892/ol.2014.2704
MLA
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9.1 (2015): 9-14.
Chicago
Lin, Y., Wang, B." Dosimetric absorption of intensity-modulated radiotherapy compared with conventional radiotherapy in breast-conserving surgery ". Oncology Letters 9, no. 1 (2015): 9-14. https://doi.org/10.3892/ol.2014.2704