Descending colo-colonic intussusception secondary to signet ring cell carcinoma: A case report

Sun,Ke-Kang; Yang,Dong; Gan,Mingqiang; Wu,Xiao‑Yang

doi:10.3892/ol.2014.2805

Descending colo-colonic intussusception secondary to signet ring cell carcinoma: A case report

Authors:
- Ke-Kang Sun
- Dong Yang
- Mingqiang Gan
- Xiao‑Yang Wu
View Affiliations

Affiliations: Department of Gastrointestinal Surgery, Kunshan First People's Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu 215300, P.R. China
Published online on: December 17, 2014 https://doi.org/10.3892/ol.2014.2805
Pages: 1380-1382

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The incidence of intussusception is low in adults, particularly in the descending colon, due to the anatomical attachment of the descending colon to the retroperitoneum. Signet ring cell histology represents ~1% of colon adenocarcinomas and is associated with young patients and a poor clinical outcome. The present study describes a case of descending colo‑colonic intussusception caused by signet ring cell carcinoma in a 27‑year‑old male. The patient presented with a history of intermittent left upper‑quadrant abdominal pain for more than six months without any evident etiology. A computed tomography scan of the abdomen revealed left‑sided colo‑colonic intussusception. Upon laparotomy, a left hemicolectomy was performed according to intraoperative frozen‑section pathology. Post‑operative pathological evaluation revealed signet ring cell carcinoma invasion of the serosa, and 31.8% (7/22) of the regional lymph nodes were positive for cancerous cells. The post‑operative course was uneventful and the patient was discharged on the tenth post‑operative day.

View Figures

View References

1	Gollub MJ: Colonic intussusception: clinical and radiographic features. AJR Am J Roentgenol. 196:W580–W585. 2011. View Article : Google Scholar : PubMed/NCBI
2	Gupta RK, Agrawal CS, Yadav R, et al: Intussusception in adults: institutional review. Int J Surg. 9:91–95. 2011. View Article : Google Scholar
3	Xu XQ, Hong T, Liu W, et al: A long adult intussusception secondary to transverse colon cancer. World J Gastroenterol. 19:3517–3519. 2013. View Article : Google Scholar : PubMed/NCBI
4	Hyngstrom JR, Hu CY, Xing Y, et al: Clinicopathology and outcomes for mucinous and signet ring colorectal adenocarcinoma: analysis from the National Cancer Data Base. Ann Surg Oncol. 19:2814–2821. 2012. View Article : Google Scholar : PubMed/NCBI
5	Thota R, Fang X and Subbiah S: Clinicopathological features and survival outcomes of primary signet ring cell and mucinous adenocarcinoma of colon: retrospective analysis of VACCR database. J Gastrointest Oncol. 5:18–24. 2014.PubMed/NCBI
6	Shia J, Klimstra DS, Bagci P, et al: TNM staging of colorectal carcinoma: issues and caveats. Semin Diagn Pathol. 29:142–153. 2012. View Article : Google Scholar : PubMed/NCBI
7	Howard N, Pranesh N and Carter P: Colo-colonic intusussception secondary to a lipoma. Int J Surg Case Rep. 3:52–54. 2012. View Article : Google Scholar : PubMed/NCBI
8	Abbes Orabi N, Paterson HM and Kartheuser A: Adult colo-colonic intussusception. Tech Coloproctol. 14:95–96. 2010. View Article : Google Scholar : PubMed/NCBI
9	Yakan S, Calkiskan C, Makay O, et al: Intussusception in adults: clinical characteristics, diagnosis and operative strategies. World J Gastroenterol. 15:1985–1989. 2009. View Article : Google Scholar : PubMed/NCBI
10	Amoruso M, D’Abbicco D, Praino S, et al: Idiopathic adult colo-colonic intussusception: case report and review of the literature. Int J Surg Case Rep. 4:416–418. 2013. View Article : Google Scholar : PubMed/NCBI
11	Wang L, Chen P, Zong L, et al: Colon angiolipoma with intussusception: a case report and literature review. World J Surg Oncol. 11:692013. View Article : Google Scholar : PubMed/NCBI
12	Fukuchi M, Tsukagoshi R, Sakurai S, et al: Adult intussusception caused by descending colon cancer during chemotherapy of stomach cancer recurrence. Case Rep Gastroenterol. 6:88–93. 2012. View Article : Google Scholar : PubMed/NCBI
13	Laufman H and Saphir O: Primary linitis plastica type of carcinoma of the colon. AMA Arch Surg. 62:79–91. 1951. View Article : Google Scholar : PubMed/NCBI
14	Kim JH, Park SJ, Park MI, et al: Early-stage primary signet ring cell carcinoma of the colon. World J Gastroenterol. 19:3895–3898. 2013. View Article : Google Scholar : PubMed/NCBI
15	Sanders GB, Hagan WH and Kinnaird DW: Adult intussusception and carcinoma of the colon. Ann Surg. 147:796–804. 1958.PubMed/NCBI
16	Azar T and Berger DL: Adult intussusception. Ann Surg. 226:134–138. 1997. View Article : Google Scholar : PubMed/NCBI
17	Marinis A, Yiallourou A, Samanides L, et al: Intussusception of the bowel in adults: a review. World J Gastroenterol. 15:407–411. 2009. View Article : Google Scholar : PubMed/NCBI
18	Goh BK, Quah HM, Chow PK, et al: Predictive factors of malignancy in adults with intussusception. World J Surg. 30:1300–1304. 2006. View Article : Google Scholar : PubMed/NCBI