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Article

Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review

  • Authors:
    • Aikeremujiang Muheremu
    • Zhen Huang
    • Xiaohui Niu
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedic Oncology Surgery, Beijing Jishuitan Hospital, Beijing 100035, P.R. China
  • Pages: 1321-1326
    |
    Published online on: December 30, 2014
       https://doi.org/10.3892/ol.2014.2837
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Abstract

Giant cell tumors of the bone (GCTB) account for 5% of all primary skeletal tumors. Although the tumors are normally benign, recurrence and metastasis of GCTB does occur. The most usual sites of a primary GCTB lesion are the distal femur and proximal tibia, and ~3% of these metastasize to the lung. Primary GCTB lesions in the spine are rare, and there have been few cases reporting the pulmonary metastasis of GCTB in the spine. The present study reports two cases of thoracic and sacral spinal GCTB lesions with pulmonary metastasis. One of the patients was a 45‑year‑old male who presented to hospital with gradually worsening pain in the left buttock during the last two years and was diagnosed with GCTB of the sacrum. The other patient was a 30‑year‑old female who complained of persistent back pain for a year and was also diagnosed with GCTB of the sacrum. Arterial embolization was performed prior to surgery and computer navigation was used during the surgery, resulting in the two patients achieving en bloc resection of their respective tumors, with satisfactory rehabilitation to follow.
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Copy and paste a formatted citation
Spandidos Publications style
Muheremu A, Huang Z and Niu X: Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review. Oncol Lett 9: 1321-1326, 2015.
APA
Muheremu, A., Huang, Z., & Niu, X. (2015). Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review. Oncology Letters, 9, 1321-1326. https://doi.org/10.3892/ol.2014.2837
MLA
Muheremu, A., Huang, Z., Niu, X."Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review". Oncology Letters 9.3 (2015): 1321-1326.
Chicago
Muheremu, A., Huang, Z., Niu, X."Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review". Oncology Letters 9, no. 3 (2015): 1321-1326. https://doi.org/10.3892/ol.2014.2837
Copy and paste a formatted citation
x
Spandidos Publications style
Muheremu A, Huang Z and Niu X: Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review. Oncol Lett 9: 1321-1326, 2015.
APA
Muheremu, A., Huang, Z., & Niu, X. (2015). Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review. Oncology Letters, 9, 1321-1326. https://doi.org/10.3892/ol.2014.2837
MLA
Muheremu, A., Huang, Z., Niu, X."Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review". Oncology Letters 9.3 (2015): 1321-1326.
Chicago
Muheremu, A., Huang, Z., Niu, X."Treatment for giant cell tumor of the spine metastasizing to the lung: A report of two cases and a literature review". Oncology Letters 9, no. 3 (2015): 1321-1326. https://doi.org/10.3892/ol.2014.2837
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