Radiofrequency ablation and percutaneous permanent iodine-125 implantation as salvage therapy for giant recurrent sclerosing epithelioid fibrosarcoma of the chest wall: A case report

Ke,Shan; Ding,Xue‑Mei; Gao,Jun; Wang,Shao‑Hong; Zhang,Jun; Kong,Jian; Sun,Wen‑Bing

doi:10.3892/ol.2015.3020

May-2015 Volume 9 Issue 5

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May-2015 Volume 9 Issue 5

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Case Report

Radiofrequency ablation and percutaneous permanent iodine-125 implantation as salvage therapy for giant recurrent sclerosing epithelioid fibrosarcoma of the chest wall: A case report

Authors:
- Shan Ke
- Xue‑Mei Ding
- Jun Gao
- Shao‑Hong Wang
- Jun Zhang
- Jian Kong
- Wen‑Bing Sun
View Affiliations / Copyright

Affiliations: Department of Hepatobiliary Surgery, Beijing Chao‑Yang Hospital Affiliated to Capital Medical University, Beijing 100043, P.R. China
Pages: 2163-2166
|
Published online on: March 9, 2015

https://doi.org/10.3892/ol.2015.3020
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Abstract

Sclerosing epithelioid fibrosarcoma (SEF) is a rare soft‑tissue sarcoma for which there is no standardized treatment regimen available. The current treatment options for SEF are resection, radiation and chemotherapy. Surgical resection remains the mainstay of therapy for SEF. However, SEF is an aggressive tumor that is prone to repeated local recurrence if not widely excised. Radiation and chemotherapy are less commonly used due to the insensitivity of SEF to these therapies. The treatment of recurrent SEF is even more challenging. The present study describes a patient who presented with a giant recurrent SEF arising from the chest wall that was accompanied by emergent bleeding. The patient was a 70‑year‑old male who had multiple comorbid diseases, including hypertension and chronic cardiac dysfunction. A computed tomography (CT) scan indicated the involvement of the sternum and anterior mediastinum. However, the patient refused any further surgery. Subsequent to careful discussion and consideration, radiofrequency (RF) ablation and percutaneous iodine‑125 implantation was administered. The emergent bleeding was successfully stopped and the tumor was eliminated using RF ablation. Percutaneous iodine‑125 implantation under CT guidance established effective control on the growth of the tumor involving the mediastinum. Despite this, the tumor recurred 6 months after treatment. The patient refused any further treatment and was discharged. In conclusion, RF ablation and percutaneous permanent iodine‑125 implantation is a feasible and safe salvage therapy for patients with recurrent SEF of the chest wall.

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1	Meis-Kindblom JM, Kindblom LG and Enzinger FM: Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma. Am J Surg Pathol. 19:979–993. 1995. View Article : Google Scholar : PubMed/NCBI
2	Antonescu CR, Rosenblum MK, Pereira P, Nascimento AG and Woodruff JM: Sclerosing epithelioid fibrosarcoma: a study of 16 cases and confirmation of a clinicopathologically distinct tumor. Am J Surg Pathol. 25:699–709. 2001. View Article : Google Scholar : PubMed/NCBI
3	Ossendorf C, Studer GM, Bode B and Fuchs B: Sclerosing epithelioid fibrosarcoma: case presentation and a systematic review. Clin Orthop Relat Res. 466:1485–1491. 2008. View Article : Google Scholar : PubMed/NCBI
4	Frattini JC, Sosa JA, Carmack S and Robert ME: Sclerosing epithelioid fibrosarcoma of the cecum: a radiation-associated tumor in a previously unreported site. Arch Pathol Lab Med. 131:1825–1828. 2007.PubMed/NCBI
5	Grunewald TG, von Luettichau I, Weirich G, et al: Sclerosing epithelioid fibrosarcoma of the bone: a case report of high resistance to chemotherapy and a survey of the literature. Sarcoma. 2010:4316272010. View Article : Google Scholar : PubMed/NCBI
6	Hanson IM, Pearson JM, Eyden BP, Slawik S and Harris M: Evidence of nerve sheath differentiation and high grade morphology in sclerosing epithelioid fibrosarcoma. J Clin Pathol. 54:721–723. 2001. View Article : Google Scholar : PubMed/NCBI
7	Watanabe K and Suzuki T: Epithelioid fibrosarcoma of the ovary. Virchows Arch. 445:410–413. 2004. View Article : Google Scholar : PubMed/NCBI
8	Argani P, Perlman EJ, Breslow NE, et al: Clear cell sarcoma of the kidney: a review of 351 cases from the National Wilms Tumor Study Group Pathology Center. Am J Surg Pathol. 24:4–18. 2000. View Article : Google Scholar : PubMed/NCBI
9	Lin ZY, Chen J and Deng XF: Treatment of hepatocellular carcinoma adjacent to large blood vessels using 1.5T MRI-guided percutaneous radiofrequency ablation combined with iodine-125 radioactive seed implantation. Eur J Radiol. 81:3079–3083. 2012. View Article : Google Scholar : PubMed/NCBI
10	Chen K, Chen G, Wang H, et al: Increased survival in hepatocellular carcinoma with iodine-125 implantation plus radiofrequency ablation: a prospective randomized controlled trial. J Hepatol. 61:1304–1311. 2014. View Article : Google Scholar : PubMed/NCBI
11	Hiraki T, Gobara H, Iguchi T, Fujiwara H, Matsui Y and Kanazawa S: Radiofrequency ablation for early-stage nonsmall cell lung cancer. Biomed Res Int. 2014:1520872014. View Article : Google Scholar : PubMed/NCBI
12	Niu L, Zhou L, Xu K and Mu F: Combination of cryosurgery and Iodine-125 seeds brachytherapy for lung cancer. J Thorac Dis. 4:504–507. 2012.PubMed/NCBI
13	Yang H, Liu YH, Xu L and Liu LH: Efficacy of permanent iodine-125 seed implants and gemcitabine chemotherapy in patients with platinum-resistant recurrent ovarian carcinoma. Asian Pac J Cancer Prev. 15:9009–9013. 2014. View Article : Google Scholar : PubMed/NCBI
14	Jiang YL, Meng N, Wang JJ, Ran WQ, Yuan HS, Qu A and Yang RJ: Percutaneous computed tomography/ultrasonography-guided permanent iodine-125 implantation as salvage therapy for recurrent squamous cell cancers of head and neck. Cancer Biol Ther. 9:959–966. 2010. View Article : Google Scholar : PubMed/NCBI
15	Staffords ES and Ward GE: Treatment of fibrosarcoma. Ann Surg. 137:639–644. 1953. View Article : Google Scholar : PubMed/NCBI
16	Lau WY and Lai EC: The current role of radiofrequency ablation in the management of hepatocellular carcinoma: a systematic review. Ann Surg. 249:20–25. 2009. View Article : Google Scholar : PubMed/NCBI
17	Fuchizaki U, Miyamori H, Kitagawa S and Kaneko S: Radiofrequency ablation for life-threatening ruptured hepatocellular carcinoma. J Hepatol. 40:354–355. 2004. View Article : Google Scholar : PubMed/NCBI
18	Sun WB, Ding XM, Ke S, Gao J and Zhang YF: Repeated radiofrequency ablation as both salvage solution and curative treatment for spontaneous rupture of giant medial lobe hepatocellular carcinoma. Chin Med J (Engl). 122:2067–2070. 2009.PubMed/NCBI
19	Manikam J, Mahadeva S, Goh KL and Abdullah BJ: Percutaneous, non-operative radio frequency ablation for haemostasis of ruptured hepatocellular carcinoma. Hepatogastroenterology. 56:227–230. 2009.PubMed/NCBI
20	Grammaticos PC: Pioneers of nuclear medicine, Madame Curie. Hell J Nucl Med. 7:30–31. 2004.PubMed/NCBI
21	Schwarz SB, Thon N, Nikolajek K, Niyazi M, Tonn JC, Belka C and Kreth FW: Iodine-125 brachytherapy for brain tumours - a review. Radiat Oncol. 7:302012. View Article : Google Scholar : PubMed/NCBI
22	Holm HH, Strøyer I, Hansen H and Stadil F: Ultrasonically guided percutaneous interstitial implantation of iodine 125 seeds in cancer therapy. Br J Radiol. 54:665–670. 1981. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Radiofrequency ablation and percutaneous permanent iodine-125 implantation as salvage therapy for giant recurrent sclerosing epithelioid fibrosarcoma of the chest wall: A case report

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