Primary pericardial extragastrointestinal stromal tumor: A case report and literature review
- Authors:
- Taner Arpaci
- Fatma Tokat
- Rabia Bozdogan Arpaci
- Tugana Akbas
- Gamze Ugurluer
- Sinan Yavuz
View Affiliations
Affiliations: Department of Radiology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey, Department of Pathology, Acibadem Maslak Hospital, Istanbul 34398, Turkey, Department of Pathology, Mersin University, Mersin 33000, Turkey, Department of Radiation Oncology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey, Department of Oncology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey
- Published online on: April 20, 2015 https://doi.org/10.3892/ol.2015.3126
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Pages:
2726-2728
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Abstract
Gastrointestinal stromal tumors (GISTs) are the most prevalent mesenchymal tumors of the gastrointestinal tract. GISTs are considered to originate from the interstitial cells of Cajal, the pacemakers of the peristaltic activity of the gastrointestinal tract. More than 95% of GISTs express KIT protein and discovered on GIST‑1. GISTs may also be encountered in locations outside the gastrointestinal tract, in which case they are referred to as extra‑GISTs (EGISTs) and often behave more aggressively. This is the case report of a primary pericardial EGIST in a 53‑year‑old male patient, confirmed by immunohistochemistry. To the best of our knowledge, this is the third case of EGIST diagnosed above the diaphragm, without being associated with the esophageal wall. Two cases of primary EGIST arising from the pleura were reported previously. In addition, this is the first reported case of an EGIST originating from the pericardium.
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