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Review

Role of microRNA-150 in solid tumors (Review)

  • Authors:
    • Fang Wang
    • Xiubao Ren
    • Xinwei Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China
  • Pages: 11-16
    |
    Published online on: April 30, 2015
       https://doi.org/10.3892/ol.2015.3170
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Abstract

MicroRNAs (miRNAs) are a family of small endogenous noncoding RNAs and their altered expression has been associated with various cellular functions, including cell development, proliferation, differentiation, apoptosis, signal transduction, tumorigenesis and cancer progression. Accumulating evidence has indicated that miRNA (miR)‑150 plays an essential regulatory role in normal hematopoiesis and tumorigenesis; therefore, miR‑150 may be a potential biomarker and therapeutic target in the diagnosis and treatment of various malignancies. The aim of the present review was to summarize the current knowledge on the functions and regulatory mechanism of miR‑150 as an oncogene or tumor suppressor gene in solid tumors. In addition, its potential application as a tumor biomarker, targeted therapeutic strategy and index of prognosis in various cancer types was investigated.
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Copy and paste a formatted citation
Spandidos Publications style
Wang F, Ren X and Zhang X: Role of microRNA-150 in solid tumors (Review). Oncol Lett 10: 11-16, 2015.
APA
Wang, F., Ren, X., & Zhang, X. (2015). Role of microRNA-150 in solid tumors (Review). Oncology Letters, 10, 11-16. https://doi.org/10.3892/ol.2015.3170
MLA
Wang, F., Ren, X., Zhang, X."Role of microRNA-150 in solid tumors (Review)". Oncology Letters 10.1 (2015): 11-16.
Chicago
Wang, F., Ren, X., Zhang, X."Role of microRNA-150 in solid tumors (Review)". Oncology Letters 10, no. 1 (2015): 11-16. https://doi.org/10.3892/ol.2015.3170
Copy and paste a formatted citation
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Spandidos Publications style
Wang F, Ren X and Zhang X: Role of microRNA-150 in solid tumors (Review). Oncol Lett 10: 11-16, 2015.
APA
Wang, F., Ren, X., & Zhang, X. (2015). Role of microRNA-150 in solid tumors (Review). Oncology Letters, 10, 11-16. https://doi.org/10.3892/ol.2015.3170
MLA
Wang, F., Ren, X., Zhang, X."Role of microRNA-150 in solid tumors (Review)". Oncology Letters 10.1 (2015): 11-16.
Chicago
Wang, F., Ren, X., Zhang, X."Role of microRNA-150 in solid tumors (Review)". Oncology Letters 10, no. 1 (2015): 11-16. https://doi.org/10.3892/ol.2015.3170
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