Primary malignant melanoma of left lower lobe of lung: A case report and review of the literature

Zhang,Xiangwei; Wang,Yang; Du,Jiajun

doi:10.3892/ol.2015.3196

July-2015 Volume 10 Issue 1

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July-2015 Volume 10 Issue 1

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Case Report

Primary malignant melanoma of left lower lobe of lung: A case report and review of the literature

Authors:
- Xiangwei Zhang
- Yang Wang
- Jiajun Du
View Affiliations / Copyright

Affiliations: Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, Shandong 250021, P.R. China, Department of Medical Imaging, Shandong Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan, Shandong 250021, P.R. China
Pages: 528-530
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Published online on: May 11, 2015

https://doi.org/10.3892/ol.2015.3196
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Abstract

Primary malignant melanoma (MM) of the lung is relatively rare, and no more than 40 cases have been reported in English literature. Here, we present a case of primary MM of the lung in a 60‑year‑old healthy asymptomatic male, detected following the observation of an abnormal shadow on a chest X‑ray. Following computed tomography and bronchoscopy examinations, the patient underwent pneumonectomy. A diagnosis of melanoma was confirmed postoperatively following immunohistochemistry. The patient received adjuvant chemotherapy postoperatively for 6 months, and is living disease-free 18 months after the surgery without any major complaints. In conclusion, primary melanoma of the lung represents a rare pathological entity. The final diagnosis of a primary MM of the lung is based on clinical, radiological and pathological findings. Surgical resection remains the cornerstone of the treatment and postoperative adjuvant chemotherapy may offer the possibility of long-time survival for certain patients.

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1	Balch CM, Soong SJ, Gershenwald JE, et al: Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol. 19:3622–3634. 2001.PubMed/NCBI
2	Bajetta E, Del Vecchio M, Bernard-Marty C, et al: Metastatic melanoma: chemotherapy. Semin Oncol. 29:427–445. 2002. View Article : Google Scholar : PubMed/NCBI
3	Wilson RW and Moran CA: Primary melanoma of the lung: a clinicopathologic and immunohistochemical study of eight cases. Am J Surg Pathol. 21:1196–1202. 1997. View Article : Google Scholar : PubMed/NCBI
4	Volpin E, Sauvanet A, Couvelard A and Belghiti J: Primary malignant melanoma of the esophagus: a case report and review of the literature. Dis Esophagus. 15:244–249. 2002. View Article : Google Scholar : PubMed/NCBI
5	Cagle P, Mace ML, Judge DM, Teague RB, Wilson RK and Greenberg SD: Pulmonary melanoma. Primary vs metastatic. Chest. 85:125–126. 1984. View Article : Google Scholar : PubMed/NCBI
6	Allen MS Jr and Drash EC: Primary melanoma of the lung. Cancer. 21:154–159. 1968. View Article : Google Scholar : PubMed/NCBI
7	Bagwell SP, Flynn SD, Cox PM and Davison JA: Primary malignant melanoma of the lung. Am Rev Respir Dis. 139:1543–1547. 1989. View Article : Google Scholar : PubMed/NCBI
8	Alghanem AA, Mehan J and Hassan AA: Primary malignant melanoma of the lung. J Surg Oncol. 34:109–112. 1987. View Article : Google Scholar : PubMed/NCBI
9	Reed RJ 3rd and Kent EM: Solitary pulmonary melanomas: Two case reports. J Thorac Cardiovasc Surg. 48:226–231. 1964.PubMed/NCBI
10	Reid JD and Mehta VT: Melanoma of the lower respiratory tract. Cancer. 19:627–631. 1966. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary malignant melanoma of left lower lobe of lung: A case report and review of the literature

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