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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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July-2015 Volume 10 Issue 1

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Case Report

Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature

  • Authors:
    • Christopher J. Schmoyer
    • Harmar D. Brereton
    • Eric W. Blomain
  • View Affiliations / Copyright

    Affiliations: Clinical Faculty, Department of Medicine, The Commonwealth Medical College, Scranton, PA 18509, USA
  • Pages: 325-328
    |
    Published online on: May 18, 2015
       https://doi.org/10.3892/ol.2015.3215
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Abstract

Aggressive fibromatosis (AF) is a benign non-encapsulated tumor of mesenchymal origin, with a tendency for local spread along fascial planes. Local invasion can lead to extensive morbidity and even mortality due to destruction of the bones, organs and soft tissues. This rare lesion is observed 1,000 times more frequently in patients with familial adenomatous polyposis or Gardner's syndrome due to the inheritance of the adenomatous polyposis coli (APC) gene. While AF does not metastasize, local recurrence is common. Distant recurrence is extremely rare, but is observed in those with a germ line APC mutation. The present study details the case of a 20‑year‑old woman with a melanoma of the right shoulder, treated definitively with surgery. The patient then developed a painful mass at the surgical site; a surgical biopsy demonstrated that the mass was AF. The patient was treated with surgical resection, radiation therapy, and a course of tamoxifen. Five years later, the patient presented with left forearm pain and diminished range of motion due to an infiltrating mass. This was excised and a clinical diagnosis of recurrent AF was made, in this patient lacking familial predisposition to the disease.
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Copy and paste a formatted citation
Spandidos Publications style
Schmoyer CJ, Brereton HD and Blomain EW: Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature. Oncol Lett 10: 325-328, 2015.
APA
Schmoyer, C.J., Brereton, H.D., & Blomain, E.W. (2015). Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature. Oncology Letters, 10, 325-328. https://doi.org/10.3892/ol.2015.3215
MLA
Schmoyer, C. J., Brereton, H. D., Blomain, E. W."Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature". Oncology Letters 10.1 (2015): 325-328.
Chicago
Schmoyer, C. J., Brereton, H. D., Blomain, E. W."Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature". Oncology Letters 10, no. 1 (2015): 325-328. https://doi.org/10.3892/ol.2015.3215
Copy and paste a formatted citation
x
Spandidos Publications style
Schmoyer CJ, Brereton HD and Blomain EW: Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature. Oncol Lett 10: 325-328, 2015.
APA
Schmoyer, C.J., Brereton, H.D., & Blomain, E.W. (2015). Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature. Oncology Letters, 10, 325-328. https://doi.org/10.3892/ol.2015.3215
MLA
Schmoyer, C. J., Brereton, H. D., Blomain, E. W."Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature". Oncology Letters 10.1 (2015): 325-328.
Chicago
Schmoyer, C. J., Brereton, H. D., Blomain, E. W."Contralateral recurrence of aggressive fibromatosis in a young woman: A case report and review of the literature". Oncology Letters 10, no. 1 (2015): 325-328. https://doi.org/10.3892/ol.2015.3215
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