|
1
|
Thomadaki H, Tsiapalis CM and Scorilas A:
Polyadenylate polymerase modulations in human epithelioid cervix
and breast cancer cell lines, treated with etoposide or cordycepin,
follow cell cycle rather than apoptosis induction. Biol Chem.
386:471–480. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Tuli HS, Sharma AK, Sandhu SS and Kashyap
D: Cordycepin: A bioactive metabolite with therapeutic potential.
Life Sci. 93:863–869. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lee HH, Park C, Jeong JW, et al: Apoptosis
induction of human prostate carcinoma cells by cordycepin through
reactive oxygen species-mediated mitochondrial death pathway. Int J
Oncol. 42:1036–1044. 2013.PubMed/NCBI
|
|
4
|
Lim L, Lee C and Chang E: Optimization of
solid state culture conditions for the production of adenosine,
cordycepin and D-mannitol in fruiting bodies of medicinal
caterpillar fungus cordyceps militaris (L: Fr.) Link (Ascomycetes).
Int J Med Mushrooms. 14:181–187. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Jeong JW, Jin CY, Park C, et al: Induction
of apoptosis by cordycepin via reactive oxygen species generation
in human leukemia cells. Toxicol In vitro. 25:817–824. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Kim HG, Shrestha B, Lim SY, et al:
Cordycepin inhibits lipopolysaccharide-induced inflammation by the
suppression of NF-kappaB through Akt and p38 inhibition in RAW
264.7 macrophage cells. Eur J Pharmacol. 545:192–199. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Pao HY, Pan BS, Leu SF and Huang BM:
Cordycepin stimulated steroidogenesis in MA-10 mouse leydig tumor
cells through the protein kinase C pathway. J Agric Food Chem.
60:4905–4913. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Yao WL, Ko BS, Liu TA, et al: Cordycepin
suppresses integrin/FAK signaling and epithelial-mesenchymal
transition in hepatocellular carcinoma. Anticancer Agents Med Chem.
14:29–34. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jagger Dv, Kredich Nm and Guarino AJ:
Inhibition of Ehrlich mouse ascites tumor growth by cordycepin.
Cancer Res. 21:216–220. 1961.PubMed/NCBI
|
|
10
|
Klenow H: Effect of cordycepin on the
incorporation of P32-orthophosphate into the nucleic acids of
ascites tumor cells in vitro. Biochem Biophys Res Commun. 5:156–9.
1961. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wu WC, Hsiao JR, Lian YY, Lin CY and Huang
BM: The apoptotic effect of cordycepin on human OEC-M1 oral cancer
cell line. Cancer Chemother Pharmacol. 60:103–111. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lee EJ, Kim WJ and Moon SK: Cordycepin
suppresses TNF-alpha-induced invasion, migration and matrix
metalloproteinase-9 expression in human bladder cancer cells.
Phytother Res. 24:1755–1761. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chen Y, Chen YC, Lin YT, Huang SH and Wang
SM: Cordycepin induces apoptosis of CGTH W-2 thyroid carcinoma
cells through the calcium-calpain-caspase 7-PARP pathway. J Agric
Food Chem. 58:11645–11652. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lee HJ, Burger P, Vogel M, et al: The
nucleoside antagonist cordycepin causes DNA double strand breaks in
breast cancer cells. Invest New Drugs. 30:1917–1925. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen LS, Stellrecht CM and Gandhi V:
RNA-directed agent, cordycepin, induces cell death in multiple
myeloma cells. Br J Haematol. 140:682–391. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Matsuda H, Akaki J, Nakamura S, et al:
Apoptosis-inducing effects of sterols from the dried powder of
cultured mycelium of Cordyceps sinensis. Chem Pharm Bull (Tokyo).
57:411–414. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kodama EN, McCaffrey RP, Yusa K and
Mitsuya H: Antileukemic activity and mechanism of action of
cordycepin against terminal deoxynucleotidyl transferase-positive
(TdT+) leukemic cells. Biochem Pharmacol. 59:273–281. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Thomadaki H, Tsiapalis CM and Scorilas A:
The effect of the polyadenylation inhibitor cordycepin on human
Molt-4 and Daudi leukaemia and lymphoma cell lines. Cancer
Chemother Pharmacol. 61:703–711. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jen CY, Lin CY, Huang BM and Leu SF:
Cordycepin induced MA-10 mouse leydig tumor cell apoptosis through
Caspase-9 pathway. Evid Based Complement Alternat Med.
2011:9845372011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yoshikawa N, Kunitomo M, Kagota S,
Shinozuka K and Nakamura K: Inhibitory effect of cordycepin on
hematogenic metastasis of B16-F1 mouse melanoma cells accelerated
by adenosine-5′-diphosphate. Anticancer Res. 29:3857–3860.
2009.PubMed/NCBI
|
|
21
|
Yoshikawa N, Yamada S, Takeuchi C, et al:
Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse
melanoma cells through the stimulation of adenosine A3 receptor
followed by glycogen synthase kinase-3beta activation and cyclin D1
suppression. Naunyn Schmiedebergs Arch Pharmacol. 377:591–595.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Nakamura K, Yoshikawa N, Yamaguchi Y, et
al: Antitumor effect of cordycepin (3′-deoxyadenosine) on mouse
melanoma and lung carcinoma cells involves adenosine A3 receptor
stimulation. Anticancer Res. 26:43–47. 2006.PubMed/NCBI
|
|
23
|
Lee SJ, Kim SK, Choi WS, Kim WJ and Moon
SK: Cordycepin causes p21WAF1-mediated G2/M cell-cycle arrest by
regulating c-Jun N-terminal kinase activation in human bladder
cancer cells. Arch Biochem Biophys. 490:103–109. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lee SJ, Moon GS, Jung KH, Kim WJ and Moon
SK: c-Jun N-terminal kinase 1 is required for cordycepin-mediated
induction of G2/M cell-cycle arrest via p21WAF1 expression in human
colon cancer cells. Food Chem Toxicol. 48:277–283. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Madi L, Ochaion A, Rath-Wolfson L, et al:
The A3 adenosine receptor is highly expressed in tumor versus
normal cells: potential target for tumor growth inhibition. Clin
Cancer Res. 10:4472–4479. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Fishman P, Bar-Yehuda S, Liang BT and
Jacobson KA: Pharmacological and therapeutic effects of A3
adenosine receptor agonists. Drug Discov Today. 17:359–366. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Koc Y, Urbano AG, Sweeney EB and McCaffrey
R: Induction of apoptosis by cordycepin in ADA-inhibited
TdT-positive leukemia cells. Leukemia. 10:1019–1024.
1996.PubMed/NCBI
|
|
28
|
Imesch P, Hornung R, Fink D and Fedier A:
Cordycepin (3′-deoxyadenosine), an inhibitor of mRNA
polyadenylation, suppresses proliferation and activates apoptosis
in human epithelial endometriotic cells in vitro. Gynecol Obstet
Invest. 72:43–49. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Choi S, Lim MH, Kim KM, Jeon BH, Song WO
and Kim TW: Cordycepin-induced apoptosis and autophagy in breast
cancer cells are independent of the estrogen receptor. Toxicol Appl
Pharmacol. 257:165–173. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Chinnaiyan AM, O'Rourke K, Yu GL, Lyons
RH, Garg M, Duan DR, Xing L, Gentz R, Ni J and Dixit VM: Signal
transduction by DR3, a death domain-containing receptor related to
TNFR-1 and CD95. Science. 274:990–992. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lee SY, Debnath T, Kim SK and Lim BO:
Anti-cancer effect and apoptosis induction of cordycepin through
DR3 pathway in the human colonic cancer cell HT-29. Food Chem
Toxicol. 60:439–447. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nicholson DW, Ali A, Thornberry NA, et al:
Identification and inhibition of the ICE/CED-3 protease necessary
for mammalian apoptosis. Nature. 376:37–43. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Tewari M, Quan LT, O'Rourke K, et al:
Yama/CPP32 beta, a mammalian homolog of CED-3, is a
CrmA-inhibitable protease that cleaves the death substrate poly
(ADP-ribose) polymerase. Cell. 81:801–809. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Fernandes-Alnemri T, Litwack G and Alnemri
ES: CPP32, a novel human apoptotic protein with homology to
Caenorhabditis elegans cell death protein Ced-3 and mammalian
interleukin-1 beta-converting enzyme. J Biol Chem. 269:30761–30764.
1994.PubMed/NCBI
|
|
35
|
Walters J, Pop C, Scott FL, et al: A
constitutively active and uninhibitable caspase-3 zymogen
efficiently induces apoptosis. Biochem J. 424:335–345. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Baik JS, Kwon HY, Kim KS, Jeong YK, Cho YS
and Lee YC: Cordycepin induces apoptosis in human neuroblastoma
SK-N-BE (2)-C and melanoma SK-MEL-2 cells. Indian J Biochem
Biophys. 49:86–91. 2012.PubMed/NCBI
|
|
37
|
Shimizu S and Tsujimoto Y: Proapoptotic
BH3-only Bcl-2 family members induce cytochrome c release, but not
mitochondrial membrane potential loss, and do not directly modulate
voltage-dependent anion channel activity. Proc Natl Acad Sci USA.
97:577–582. 2000.PubMed/NCBI
|
|
38
|
Lee HH, Jeong JW, Lee JH, et al:
Cordycepin increases sensitivity of Hep3B human hepatocellular
carcinoma cells to TRAIL-mediated apoptosis by inactivating the JNK
signaling pathway. Oncol Rep. 30:1257–1264. 2013.PubMed/NCBI
|
|
39
|
Chen YH, Hao LJ, Hung CP, Chen JW, Leu SF
and Huang BM: Apoptotic effect of cisplatin and cordycepin on OC3
human oral cancer cells. Chin J Integr Med. 20:624–632. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chen YH, Wang JY, Pan BS, et al:
Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK
pathways in human head and neck tumor cells. Onco Targets Ther.
6:983–998. 2013.PubMed/NCBI
|
|
41
|
Tian X, Zhao X, Yin K, Mao D, Yang J and
Wang Q: Immunoregulation ability comparison of cordycepin and
Flammulina velutipes polysaccharide in rat body after exhaustive
exercise. Int J Biol Biol Sci. 2:136–142. 2013.
|
