Advantage of transurethral resection with narrow band imaging for non-muscle invasive bladder cancer

Kobatake,Kohei; Mita,Koji; Ohara,Shinya; Kato,Masao

doi:10.3892/ol.2015.3280

August-2015 Volume 10 Issue 2

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August-2015 Volume 10 Issue 2

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Article

Advantage of transurethral resection with narrow band imaging for non-muscle invasive bladder cancer

Authors:
- Kohei Kobatake
- Koji Mita
- Shinya Ohara
- Masao Kato
View Affiliations / Copyright

Affiliations: Department of Urology, Hiroshima City Asa Hospital, Hiroshima 731‑0293, Japan
Pages: 1097-1102
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Published online on: May 27, 2015

https://doi.org/10.3892/ol.2015.3280
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Abstract

The aim of the present study was to compare the benefits of transurethral resection (TUR) under narrow band imaging (NBI-TUR) and TUR under conventional white light imaging (WLI-TUR) for non‑muscle invasive bladder cancer (NMIBC). The study cohort consisted of 135 patients with NMIBC who were followed up for ≥1 year after TUR and who received no additional post‑operative treatment. In the WLI‑TUR group (n=78), systematic intravesical observation under WLI was followed by a multiple site biopsy (MSB), after which lesions detected as positive findings were resected completely under WLI. In the NBI‑TUR group (n=57), similar observation under WLI was followed by systematic intravesical observation under NBI. Following MSB under NBI, TUR was performed for all lesions detected as positive findings under NBI. The sensitivity, specificity, positive‑predictive value, negative‑predictive value (NPV) and accuracy in the NBI‑TUR group were calculated using results from the cystoscopical and pathological examinations of MSB samples under WLI and NBI. The tumor recurrence rate was analyzed in the two groups. Background factors did not differ significantly between the two groups, with the exception of the observation period (31.0 vs. 15.0 months; P<0.01). The procedure under NBI exhibited significantly higher sensitivity (95.0 vs. 70.0%; P<0.01) and NPV (97.1 vs. 86.8%; P<0.01) compared with the procedure under WLI. The 1‑year recurrence rate in the NBI‑TUR group was significantly lower than that in the WLI‑TUR group (21.1 vs. 39.7%; P=0.016). In conclusion, the present study indicated that NBI‑TUR is more advantageous than conventional WLI-TUR for patients with NMIBC.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Advantage of transurethral resection with narrow band imaging for non-muscle invasive bladder cancer

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