|
1
|
Klaus A and Birchmeier W: Wnt signalling
and its impact on development and cancer. Nat Rev Caner. 8:387–398.
2008. View
Article : Google Scholar
|
|
2
|
Anastas JN and Moon RT: WNT signalling
pathways as therapeutic targets in cancer. Nat Rev Caner. 13:11–26.
2013. View
Article : Google Scholar
|
|
3
|
White BD, Chien AJ and Dawson DW:
Dysregulation of Wnt/β-catenin signalling in gastrointestinal
cancers. Gastroenterology. 142:219–232. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Papkoff J, Rubinfeld B, Schryver B and
Polakis P: Wnt-1 regulates free pools of catenins and stabilizes
APC-catenin complexes. Mol Cell Biol. 16:2128–2134. 1996.PubMed/NCBI
|
|
5
|
Korinek V, Barker N, Morin PJ, et al:
Constitutive transcriptional activation by a β-catenin-Tcf complex
in APC-/-colon carcinoma. Science. 275:1784–1787. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Morin PJ, Sparks AB, Korinek V, et al:
Activation of β-catenin-Tcf signaling in colon cancer by mutations
in β-catenin or APC. Science. 275:1787–1790. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Martensson A, Oberg A, Jung A, et al:
Beta-catenin expression in relation to genetic instability and
prognosis in colorectal cancer. Oncol Rep. 17:447–452.
2007.PubMed/NCBI
|
|
8
|
Wanitsuwan W, Kanngurn S,
Boonpipattanapong T, et al: Overall expression of beta-catenin
outperforms its nuclear accumulation in predicting outcomes of
colorectal cancers. World J Gastroenterol. 14:6052–6059. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Elzagheid A, Buhmeida A, Korkeila E, et
al: Nuclear beta-catenin expression as a prognostic factor in
advanced colorectal carcinoma. World J Gastroenterol. 14:3866–3871.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Brabletz T, Jung A, Reu S, et al: Variable
beta-catenin expression in colorectal cancers indicates tumor
progression driven by the tumor environment. Proc Natl Acad Sci
USA. 98:10356–10361. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Brabletz T, Jung A, Hermann K, Günther K,
Hohenberger W and Kirchner T: Nuclear overexpression of the
oncoprotein beta-catenin in colorectal cancer is localized
predominantly at the invasion front. Pathol Res Pract. 194:701–704.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gabbert H, Wagner R, Moll R and Gerharz
CD: Tumor dedifferentiation: an important step in tumor invasion.
Clin Exp Metastasis. 3:257–279. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hlubek F, Brabletz T, Budczies J, Pfeiffer
S, Jung A and Kirchner T: Heterogeneous expression of
Wnt/beta-catenin target genes within colorectal cancer. Int J
Cancer. 121:1941–1948. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Behrens J: The role of Wnt signalling
pathway in colorectal tumorigenesis. Biochem Soc Trans. 33:672–675.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Stanczak A, Stec R, Bodnar L, et al:
Prognostic significance of Wnt-1, beta-Catenin and E-Cadherin
expression in advanced colorectal carcinoma. Pathol Oncol Res.
17:955–963. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Khor TO, Gul YA, Ithnin H and Seow HF: A
comparative study of expression of Wnt-1, WISP-1, survivin and
cyclin-D1 in colorectal carcinoma. Int J Colorectal Dis.
21:291–300. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Holcombe RF, Marsh JL, Waterman ML, Lin F,
et al: Expression of Wnt ligands and Frizzled receptors in colonic
mucosa and in colon carcinoma. Mol Pathol. 55:220–226. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
De A: Wnt/Ca2+ signaling pathway: a brief
overview. Acta Biochim Biophys Shanghai 2011. 43:745–756. 2011.
|
|
19
|
Chen J, Röcken C, Lofton-Day C, Schulz HU,
et al: Molecular analysis of APC promoter methylation and protein
expression in colorectal cancer metastasis. Carcinogenesis.
26:37–43. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Baylin SB and Herman JG: DNA
hypermethylation in tumorigenesis: epigenetics joins genetics.
Trends Genet. 16:168–174. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wu JM, Fackler MJ, Halushka MK, Molavi DW,
et al: Heterogeneity of breast cancer metastases: comparison of
therapeutic target expression and promoter methylation between
primary tumors and their multifocal metastases. Clin Cancer Res.
14:1938–1946. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Fearon ER and Vogelstein B: A genetic
model for colorectal tumorigenesis. Cell. 61:759–767. 1990.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Collins VP, Loeffler RK and Tivey H:
Observations on growth rates of human tumors. Am J Roentgenol
Radium Ther Nucl Med. 76:988–1000. 1956.PubMed/NCBI
|
|
24
|
Klein CA: Parallel progression of primary
tumours and metastases. Nat Rev Cancer. 9:302–312. 2009. View Article : Google Scholar : PubMed/NCBI
|