Primary malignant hepatic paraganglioma mimicking liver tumor: A case report

You,Zhen; Deng,Yilei; Shrestha,Anuj; Li,Fuyu; Cheng,Nansheng

doi:10.3892/ol.2015.3318

August-2015 Volume 10 Issue 2

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August-2015 Volume 10 Issue 2

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Case Report

Primary malignant hepatic paraganglioma mimicking liver tumor: A case report

Authors:
- Zhen You
- Yilei Deng
- Anuj Shrestha
- Fuyu Li
- Nansheng Cheng
View Affiliations / Copyright

Affiliations: Department of Biliary Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China
Pages: 1176-1178
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Published online on: June 4, 2015

https://doi.org/10.3892/ol.2015.3318
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Abstract

An extra-adrenal pheochromocytoma is also known as a paraganglioma. The present study reported the case of a 47-year-old female patient with an extremely rare primary nonfunctioning hepatic paraganglioma without any clinical signs and symptoms. A computed tomography scan of the entire abdomen region revealed a hyper‑enhanced, well‑marginated round mass located in segment 3 of the liver. A preoperative diagnosis of hepatocellular carcinoma was established and a left lateral hepatic lobectomy was performed. During the removal of the mass, the patient experienced extreme fluctuations in blood pressure. Analysis of hepatic and peripheral venous blood test results confirmed the increase of noradrenaline secretion. Postoperatively, the patient's blood pressure and catecholamine level returned to the normal range. However, three years after surgery, a plasma catecholamine examination revealed a high noradrenaline level. Abdominal magnetic resonance imaging scans revealed two metastases, located in the spleen and below the right posterior lobe of the liver, which were identified as malignant paragangliomas. Therefore, the patient was diagnosed with primary malignant hepatic paraganglioma recurrence three years after hepatic resection.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary malignant hepatic paraganglioma mimicking liver tumor: A case report

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Abstract

Figure 1

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