Castleman's disease presenting in the lungs: A report of two cases

Cao,Weijun; Liang,Shuo; Liu,Jinming; Bai,Jiuwu; Li,Huiping

doi:10.3892/ol.2015.3354

August-2015 Volume 10 Issue 2

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

August-2015 Volume 10 Issue 2

Full Size Image

Article

Castleman's disease presenting in the lungs: A report of two cases

Authors:
- Weijun Cao
- Shuo Liang
- Jinming Liu
- Jiuwu Bai
- Huiping Li
View Affiliations / Copyright

Affiliations: Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, P.R. China
Pages: 1041-1043
|
Published online on: June 10, 2015

https://doi.org/10.3892/ol.2015.3354
Expand metrics +

Abstract

Castleman's disease (CD) is a rare disease that most commonly occurs in the mediastinum. The lung is a rare site in which CD may occur. The current study reported 2 cases of CD localized in the lungs. Computed tomography imaging identified a high‑density mass in the lungs of the two patients. Biopsy and pathological examinations indicated that one case presented features of two CD types (hyaline‑vascular and plasma cell types), while the other case suffered from multicentric CD. The present study highlighted the typical clinical features of CD in the lungs. In addition, it is proposed that a diagnosis of CD should be considered for certain patients with masses in the lungs, and a biopsy should be performed to facilitate diagnosis and treatment.

View Figures

View References

1	Castleman B and Towne VW: Case records of the Massachusetts General Hospital; weekly clinicopathological exercises; founded by Richard C. Cabot. N Engl J Med. 251:396–400. 1954.PubMed/NCBI
2	Cronin DM and Warnke RA: Castleman disease: an update on classification and the spectrum of associated lesions. Adv Anat Pathol. 16:236–246. 2009. View Article : Google Scholar : PubMed/NCBI
3	Bonekamp D, Horton KM, Hruban RH and Fishman EK: Castleman disease: The great mimic. Radiographics. 31:1793–1807. 2011. View Article : Google Scholar : PubMed/NCBI
4	Zhou LP, Zhang B, Peng WJ, Yang WT, Guan YB and Zhou KR: Imaging findings of Castleman disease of the abdomen and pelvis. Abdom Imaging. 33:482–488. 2008. View Article : Google Scholar : PubMed/NCBI
5	Guo H, Shen Y, Wang WL, et al: Castleman disease mimicked pancreatic carcinoma: Report of two cases. World J Surg Oncol. 10:1542012. View Article : Google Scholar : PubMed/NCBI
6	Newlon JL, Couch M and Brennan J: Castleman's disease: Three case reports and a review of the literature. Ear Nose Throat J. 86:414–418. 2007.PubMed/NCBI
7	Puram SV, Hasserjian RP, Faquin WC, Lin HW and Rocco JW: Castleman disease presenting in the neck: Report of a case and review of the literature. Am J Otolaryngol. 34:239–244. 2013. View Article : Google Scholar : PubMed/NCBI
8	Macedo JE, Abreu I, Marques M, Henrique R and Araújo A: A clinical case of Castleman's disease. J Thorac Oncol. 2:259–260. 2007. View Article : Google Scholar : PubMed/NCBI
9	Lu ZH and Wu M: Localized Castleman disease of plasma cell type in the abdomen. Chin Med J (Engl). 124:2789–2791. 2011.PubMed/NCBI
10	Parker MS: Multicentric hyaline-vascular Castleman's disease. Clin Radiol. 62:707–710. 2007. View Article : Google Scholar : PubMed/NCBI
11	Kim TJ, Han JK, Kim YH, Kim TK and Choi BI: Castleman disease of the abdomen: Imaging spectrum and clinicopathologic correlations. J Comput Assist Tomogr. 25:207–214. 2001. View Article : Google Scholar : PubMed/NCBI
12	Talat N, Belgaumkar AP and Schulte KM: Surgery in Castleman's disease: A systematic review of 404 published cases. Ann Surg. 255:677–684. 2012. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Castleman's disease presenting in the lungs: A report of two cases

This article is mentioned in:

Abstract

Figure 1

Figure 2

Figure 3

Related Articles