Management of nasopharyngeal angiofibroma in a 72-year-old male through a sublabial and buccolabial incision approach: A case report and literature review

Zhang,Huan‑Kang; Wang,Jing‑Jing; Liu,Zhuo‑Fu; Wang,De‑Hui

doi:10.3892/ol.2015.3410

September-2015 Volume 10 Issue 3

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September-2015 Volume 10 Issue 3

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Management of nasopharyngeal angiofibroma in a 72-year-old male through a sublabial and buccolabial incision approach: A case report and literature review

Authors:
- Huan‑Kang Zhang
- Jing‑Jing Wang
- Zhuo‑Fu Liu
- De‑Hui Wang
View Affiliations / Copyright

Affiliations: Department of Otolaryngology, Fudan University Affiliated Eye, Ear, Nose and Throat Hospital, Shanghai 200031, P.R. China

Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 1267-1270
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Published online on: June 22, 2015

https://doi.org/10.3892/ol.2015.3410
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Abstract

Nasopharyngeal angiofibroma (NA) primarily affects adolescent males. The incidence of NA in the elderly, however, is extremely low. The present study describes a 72-year-old male with NA that presented with typical symptoms and radiological findings. The location and extension of the tumor was too lateral and inferior to be effectively resected by an endoscopic approach. Therefore, a combination of endoscopic and open approaches was considered. The tumor was completely resected using an image‑guided endoscopic‑assisted sublabial and buccolabial incision approach. The post‑operative histopathological and immunohistochemical analysis confirmed the diagnosis of NA. The present study demonstrated the occurrence of NA in the elderly, and highlighted the potential of an image‑guided endoscopic‑assisted sublabial and buccolabial incision approach for the treatment of NA in the elderly.

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1	Sun XC, Wang DH, Yu HP, et al: Analysis of risk factors associated with recurrence of nasopharyngeal angiofibroma. J Otolaryngol Head Neck Surg. 39:56–61. 2010.PubMed/NCBI
2	Boghani Z, Husain Q, Kanumuri VV, et al: Juvenile nasopharyngeal angiofibroma: A systematic review and comparison of endoscopic, endoscopic-assisted and open resection in 1047 cases. Laryngoscope. 123:859–869. 2013. View Article : Google Scholar : PubMed/NCBI
3	Huang Y, Liu Z, Wang J, et al: Surgical management of juvenile nasopharyngeal angiofibroma: Analysis of 162 cases from 1995 to 2012. Laryngoscope. 124:1942–1946. 2014. View Article : Google Scholar : PubMed/NCBI
4	Tang IP, Shashinder S, Gopala Krishnan G and Narayanan P: Juvenile nasopharyngeal angiofibroma in a tertiary centre: Ten-year experience. Singapore Med J. 50:261–264. 2009.PubMed/NCBI
5	Paris J, Guelfucci B, Moulin G, et al: Diagnosis and treatment of juvenile nasopharyngeal angiofibroma. Eur Arch Otorhinolaryngol. 258:120–124. 2001. View Article : Google Scholar : PubMed/NCBI
6	Sun XC, Li H, Liu ZF, et al: Endoscopic-assisted sublabial and buccolabial incision approach for juvenile nasopharyngeal angiofibroma with extensive infratemporal fossa extension. Int J Pediatr Otorhinolaryngol. 76:1501–1506. 2012. View Article : Google Scholar : PubMed/NCBI
7	Conley J, Healey WV, Blaugrund SM and Erzin KH: Nasopharyngeal angiofibroma in the juvenile. Surg Gynecol Obstet. 126:825–837. 1968.PubMed/NCBI
8	Ewing JA and Shively EH: Angiofibroma: a rare case in an elderly female. Otolaryngol Head Neck Surg. 89:602–603. 1981.PubMed/NCBI
9	Shaheen HB: Nasopharyngeal fibroma. J Laryngol Otol. 45:259–264. 1930. View Article : Google Scholar
10	Patrocínio JA, Patrocínio LG, Borba BH, et al: Nasopharyngeal angiofibroma in an elderly woman. Am J Otolaryngol. 26:198–200. 2005. View Article : Google Scholar : PubMed/NCBI
11	Bornemann A and Schmalbruch H: Anti-vimentin staining in muscle pathology. Neuropathol Appl Neurobiol. 19:414–419. 2009. View Article : Google Scholar
12	Pusztaszeri MP, Seelentag W and Bosman FT: Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues. J Histochem Cytochem. 54:385–395. 2006. View Article : Google Scholar : PubMed/NCBI
13	Farag MM, Ghanimah SE, Ragaie A and Saleem TH: Hormonal receptors in juvenile nasopharyngeal angiofibroma. Laryngoscope. 97:208–211. 1987. View Article : Google Scholar : PubMed/NCBI
14	Ferrini RL and Barrett-Connor E: Sex hormones and age: a cross-sectional study of testosterone and estradiol and their bioavailable fractions in community-dwelling men. Am J Epidemiol. 147:750–754. 1998. View Article : Google Scholar : PubMed/NCBI
15	Laughlin GA, Barrett-Connor E and Bergstrom J: Low serum testosterone and mortality in older men. J Clin Endocrinol Metab. 93:68–75. 2008. View Article : Google Scholar : PubMed/NCBI
16	Douglas R and Wormald PJ: Endoscopic surgery for juvenile nasopharyngeal angiofibroma: Where are the limits? Curr Opin Otolaryngol Head Neck Surg. 14:1–5. 2006. View Article : Google Scholar : PubMed/NCBI
17	Khalifa MA and Ragab SM: Endoscopic assisted antral window approach for type III nasopharyngeal angiofibroma with infratemporal fossa extension. Int J Pediatr Otorhinolaryngol. 72:1855–1860. 2008. View Article : Google Scholar : PubMed/NCBI
18	Gallia GL, Ramanathan M Jr, Blitz AM and Reh DD: Expanded endonasal endoscopic approach for resection of a juvenile nasopharyngeal angiofibroma with skull base involvement. J Clin Neurosci. 17:1423–1427. 2010. View Article : Google Scholar : PubMed/NCBI
19	Farhadi M, Jalessi M, Sharifi G, et al: Use of image guidance in endoscopic endonasal surgeries: A 5-year experience. B-ENT. 7:277–282. 2011.PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Management of nasopharyngeal angiofibroma in a 72-year-old male through a sublabial and buccolabial incision approach: A case report and literature review

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