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Case Report

Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review

  • Authors:
    • Hongwei Shen
    • Jianhong Shang
    • Gang Niu
    • Jun Liu
    • Zeshan You
    • Shanyang He
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, The First Affiliated Hospital, Sun Yat‑Sen University, Guangzhou, Guangdong 510080, P.R. China
  • Pages: 2579-2583
    |
    Published online on: July 15, 2015
       https://doi.org/10.3892/ol.2015.3497
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Abstract

Ovarian cancer associated with deep venous thrombosis (DVT) is an uncommon, potentially life-threatening condition. The primary therapeutic strategy for the treatment of this condition is up-front primary cytoreductive surgery, with placement of an inferior vena cava (IVC) filter prior to surgery to prevent fatal pulmonary embolism. The present study describes the case of a 49-year-old female, who presented with DVT unresponsive to anticoagulant therapy in the lower extremities prior to the diagnosis of ovarian cancer. During the search for the underlying malignancy, transvaginal sonography (TVS) revealed a cystic solid mass in the pelvic cavity. Subsequently, the patient underwent up-front primary cytoreductive surgery without placement of a preoperative IVC filter, followed by six cycles of chemotherapy. The patient was diagnosed with ovarian clear cell adenocarcinoma stage IIIC, complicated by DVT, and had survived >3 years without relapse at the time of completion of the present study. The successful outcome of the present case demonstrated that occult primary cancer should be suspected in patients with DVT unresponsive to anticoagulant therapy. The present study also indicated that up-front primary cytoreductive surgery without placement of an IVC filter represents an effective potential strategy for the treatment of advanced ovarian cancer associated with DVT, as the thrombus strongly adheres to the vessel wall following organization.
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Copy and paste a formatted citation
Spandidos Publications style
Shen H, Shang J, Niu G, Liu J, You Z and He S: Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review. Oncol Lett 10: 2579-2583, 2015.
APA
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., & He, S. (2015). Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review. Oncology Letters, 10, 2579-2583. https://doi.org/10.3892/ol.2015.3497
MLA
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., He, S."Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review". Oncology Letters 10.4 (2015): 2579-2583.
Chicago
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., He, S."Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review". Oncology Letters 10, no. 4 (2015): 2579-2583. https://doi.org/10.3892/ol.2015.3497
Copy and paste a formatted citation
x
Spandidos Publications style
Shen H, Shang J, Niu G, Liu J, You Z and He S: Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review. Oncol Lett 10: 2579-2583, 2015.
APA
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., & He, S. (2015). Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review. Oncology Letters, 10, 2579-2583. https://doi.org/10.3892/ol.2015.3497
MLA
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., He, S."Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review". Oncology Letters 10.4 (2015): 2579-2583.
Chicago
Shen, H., Shang, J., Niu, G., Liu, J., You, Z., He, S."Optimal cytoreductive surgery for underlying ovarian cancer associated with deep venous thrombosis without placement of inferior vena cava filter: A case report and literature review". Oncology Letters 10, no. 4 (2015): 2579-2583. https://doi.org/10.3892/ol.2015.3497
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