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Case Report

False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature

  • Authors:
    • Yi‑Shan Yu
    • Wan‑Hu Li
    • Ming‑Huan Li
    • Xue Meng
    • Li Kong
    • Jin‑Ming Yu
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, Shandong 250117, P.R. China, Department of Radiology, Shandong Cancer Hospital and Institute, Shandong University, Jinan, Shandong 250117, P.R. China
  • Pages: 3585-3590
    |
    Published online on: September 25, 2015
       https://doi.org/10.3892/ol.2015.3753
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Abstract

Bone metastases are common in prostate cancer. However, differentiating neoplastic from non‑neoplastic alterations of bone on images is challenging. In the present report, a rare case of bone marrow reconversion on magnetic resonance imaging (MRI) assessment, which may lead to a false‑positive diagnosis of disease progression of bone metastases in hormone‑resistant prostate cancer, is presented. Furthermore, a review of the literature regarding the pitfalls of images for response assessment, including the ‘flare’ pheno­menon on bone scintigraphy, computed tomography (CT), positron emission tomography/CT and marrow reconversion on MRI is also provided. These inaccuracies, which may lead to a premature termination of an efficacious treatment, should be carefully considered by the radiologists and oncologists involved in clinical trials. The case reported in the present study showed how to assess the early therapeutic response and select the appropriate treatment for the patient when these pitfalls are encountered on clinical images.
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Copy and paste a formatted citation
Spandidos Publications style
Yu YS, Li WH, Li MH, Meng X, Kong L and Yu JM: False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature. Oncol Lett 10: 3585-3590, 2015.
APA
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., & Yu, J. (2015). False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature. Oncology Letters, 10, 3585-3590. https://doi.org/10.3892/ol.2015.3753
MLA
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., Yu, J."False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature". Oncology Letters 10.6 (2015): 3585-3590.
Chicago
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., Yu, J."False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature". Oncology Letters 10, no. 6 (2015): 3585-3590. https://doi.org/10.3892/ol.2015.3753
Copy and paste a formatted citation
x
Spandidos Publications style
Yu YS, Li WH, Li MH, Meng X, Kong L and Yu JM: False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature. Oncol Lett 10: 3585-3590, 2015.
APA
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., & Yu, J. (2015). False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature. Oncology Letters, 10, 3585-3590. https://doi.org/10.3892/ol.2015.3753
MLA
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., Yu, J."False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature". Oncology Letters 10.6 (2015): 3585-3590.
Chicago
Yu, Y., Li, W., Li, M., Meng, X., Kong, L., Yu, J."False‑positive diagnosis of disease progression by magnetic resonance imaging for response assessment in prostate cancer with bone metastases: A case report and review of the pitfalls of images in the literature". Oncology Letters 10, no. 6 (2015): 3585-3590. https://doi.org/10.3892/ol.2015.3753
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