Spinal chordoid meningioma in a child: A case report and review of the literature

Wu,Liang; Yang,Tao; Fang,Jingyi; Zhang,Junting; Xu,Yulun

doi:10.3892/ol.2015.3765

December-2015 Volume 10 Issue 6

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December-2015 Volume 10 Issue 6

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Case Report

Spinal chordoid meningioma in a child: A case report and review of the literature

Authors:
- Liang Wu
- Tao Yang
- Jingyi Fang
- Junting Zhang
- Yulun Xu
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China, Department of Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China
Pages: 3727-3731
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Published online on: September 29, 2015

https://doi.org/10.3892/ol.2015.3765
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Abstract

As an uncommon subtype of meningioma, chordoid meningioma (CM) of the spinal canal is extremely rare. There have been only two reported cases of intraspinal CM in the literature, and this lesion has not been previously reported in the pediatric age group. To the best of our knowledge, the present study reports the first case of spinal chordoid meningioma in a pediatric patient. A 12‑year‑old female presented with a 3‑month history of progressive numbness and weakness in the right‑side limbs, and intermittent pain in the neck and right shoulder. Spinal magnetic resonance imaging (MRI) revealed an intraspinal lesion at the C2‑3 level with irregularly heterogeneous enhancement. The patient underwent a C2‑3 laminotomy. Due to adhesion to the dura and proximity to the vertebral artery, the tumor was partially removed intraoperatively. The post‑operative course was uneventful and the symptoms were apparently relieved. The patient experienced recurrence 5 years subsequent to surgery. MRI revealed an extradural regrown tumor at the C2‑5 level. Partial removal combined with radiotherapy was performed. However, the patient experienced progression of tetraplegia and succumbed to severe pneumonia and respiratory failure 5 months subsequent to the second surgery. In the present study, the clinicoradiological findings and treatment outcome of this rare entity are discussed, in addition to a review of the relevant literature. Spinal CMs should be included in the differential diagnosis of intraspinal tumors of the pediatric spine. Multidisciplinary treatment, consisting of total surgical removal and adjuvant radiotherapy, should be considered due to the aggressive nature of this abnormality and the risk of long‑term recurrence.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Spinal chordoid meningioma in a child: A case report and review of the literature

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