Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer

Shen,Zhihong; Liu,Xibo; Lu,Baochun; Ye,Minfeng

doi:10.3892/ol.2015.4023

February-2016 Volume 11 Issue 2

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February-2016 Volume 11 Issue 2

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Case Report

Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer

Authors:
- Zhihong Shen
- Xibo Liu
- Baochun Lu
- Minfeng Ye
View Affiliations / Copyright

Affiliations: Department of General Surgery, Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing, Zhejiang 312000, P.R. China
Pages: 1077-1080
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Published online on: December 10, 2015

https://doi.org/10.3892/ol.2015.4023
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Abstract

Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric cancer with an extremely poor prognosis. The current study reports a rare case of HAS, characterized by gastric cancer and infiltration of cancer cells into the left liver lobe, as well as lymphadenectasis. The expression of α‑fetoprotein (AFP) was markedly increased in the tumor cells of the liver neoplasms. A gastric biopsy indicated highly, moderately and poorly differentiated papillary adenocarcinoma. The patient underwent two cycles of chemotherapy with oxaliplatin (130 mg; day 1) and capecitabine (2 mg, twice daily; days 1‑14). At 7 weeks after the chemotherapy, an expanded gastrectomy and radical resection of left lung lobe were performed on the operable lesion. AFP expression was significantly decreased following the procedure. A literature review was also conducted by searching PubMed/Medline, indicating that surgery and chemotherapy may positively affect the outcomes of HAS patients.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer

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Abstract

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