Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer

  • Authors:
    • Zhihong Shen
    • Xibo Liu
    • Baochun Lu
    • Minfeng Ye
  • View Affiliations

  • Published online on: December 10, 2015     https://doi.org/10.3892/ol.2015.4023
  • Pages: 1077-1080
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Abstract

Hepatoid adenocarcinoma of the stomach (HAS) is a rare type of gastric cancer with an extremely poor prognosis. The current study reports a rare case of HAS, characterized by gastric cancer and infiltration of cancer cells into the left liver lobe, as well as lymphadenectasis. The expression of α‑fetoprotein (AFP) was markedly increased in the tumor cells of the liver neoplasms. A gastric biopsy indicated highly, moderately and poorly differentiated papillary adenocarcinoma. The patient underwent two cycles of chemotherapy with oxaliplatin (130 mg; day 1) and capecitabine (2 mg, twice daily; days 1‑14). At 7 weeks after the chemotherapy, an expanded gastrectomy and radical resection of left lung lobe were performed on the operable lesion. AFP expression was significantly decreased following the procedure. A literature review was also conducted by searching PubMed/Medline, indicating that surgery and chemotherapy may positively affect the outcomes of HAS patients.
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February-2016
Volume 11 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Shen Z, Liu X, Lu B and Ye M: Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer. Oncol Lett 11: 1077-1080, 2016
APA
Shen, Z., Liu, X., Lu, B., & Ye, M. (2016). Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer. Oncology Letters, 11, 1077-1080. https://doi.org/10.3892/ol.2015.4023
MLA
Shen, Z., Liu, X., Lu, B., Ye, M."Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer". Oncology Letters 11.2 (2016): 1077-1080.
Chicago
Shen, Z., Liu, X., Lu, B., Ye, M."Hepatoid adenocarcinoma of the stomach: A case report of a rare type of gastric cancer". Oncology Letters 11, no. 2 (2016): 1077-1080. https://doi.org/10.3892/ol.2015.4023