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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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March-2016 Volume 11 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Case Report

Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report

  • Authors:
    • Runmei Li
    • Fang Yan
    • Liang Liu
    • Hui Li
    • Baozhu Ren
    • Zhenzhen Hui
    • Xiubao Ren
  • View Affiliations / Copyright

    Affiliations: Department of Immunology, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin 300060, P.R. China
  • Pages: 1885-1888
    |
    Published online on: January 14, 2016
       https://doi.org/10.3892/ol.2016.4109
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Abstract

Liver cancer, of which the most common form is hepatocellular carcinoma (HCC), is one of the most lethal cancers worldwide. Immunotherapy based on the direct attack of tumor cells and the stimulation of an antitumor immune response may represent a novel strategy to control HCC recurrence and metastasis. The present study reports the case of a patient with HCC, and describes the safety and feasibility of successful administration with a mass of autologous activated T cells on numerous occasions subsequent to liver transplantation (LT), in order to kill the residual tumor cells and stimulate the immune system. A large number of infused activated T cells may pose a potential risk to the allograft. However, no acute or delayed adverse effects of cytokine‑induced killer cell (CIK) therapy, or other symptoms of secondary acute host‑versus‑graft disease (HVGD), were observed. These observations demonstrate the relatively low toxicity of CIK infusion to a patient that has undergone LT, and more importantly, they demonstrate the feasibility of this immunotherapy for the patient, following successful LT.
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Copy and paste a formatted citation
Spandidos Publications style
Li R, Yan F, Liu L, Li H, Ren B, Hui Z and Ren X: Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncol Lett 11: 1885-1888, 2016.
APA
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., & Ren, X. (2016). Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncology Letters, 11, 1885-1888. https://doi.org/10.3892/ol.2016.4109
MLA
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., Ren, X."Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report". Oncology Letters 11.3 (2016): 1885-1888.
Chicago
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., Ren, X."Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report". Oncology Letters 11, no. 3 (2016): 1885-1888. https://doi.org/10.3892/ol.2016.4109
Copy and paste a formatted citation
x
Spandidos Publications style
Li R, Yan F, Liu L, Li H, Ren B, Hui Z and Ren X: Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncol Lett 11: 1885-1888, 2016.
APA
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., & Ren, X. (2016). Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report. Oncology Letters, 11, 1885-1888. https://doi.org/10.3892/ol.2016.4109
MLA
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., Ren, X."Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report". Oncology Letters 11.3 (2016): 1885-1888.
Chicago
Li, R., Yan, F., Liu, L., Li, H., Ren, B., Hui, Z., Ren, X."Cytokine‑induced killer cell therapy for the treatment of primary hepatocellular carcinoma subsequent to liver transplantation: A case report". Oncology Letters 11, no. 3 (2016): 1885-1888. https://doi.org/10.3892/ol.2016.4109
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