Giant non‑functional parathyroid cyst: A case report

Zhang,Xu; Yuan,Jun‑Hui; Feng,Lu; Shan,Dong‑Qiu; Wu,Jun‑Fu; Liu,Shan‑Ting

doi:10.3892/ol.2016.4181

Giant non‑functional parathyroid cyst: A case report

Authors:
- Xu Zhang
- Jun‑Hui Yuan
- Lu Feng
- Dong‑Qiu Shan
- Jun‑Fu Wu
- Shan‑Ting Liu
View Affiliations

Affiliations: Department of Head, Neck and Thyroid, Affiliated Tumor Hospital, Zhengzhou University, Zhengzhou, Henan 450008, P.R. China, Department of Radiology, Affiliated Tumor Hospital, Zhengzhou University, Zhengzhou, Henan 450008, P.R. China
Published online on: February 3, 2016 https://doi.org/10.3892/ol.2016.4181
Pages: 2237-2240

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Giant parathyroid cysts (PCs) are a rare entity and possess a benign clinical course. PCs may be functional or non‑functional, depending on the ability of the cyst to secrete parathyroid hormone (PTH). The present study reports a rare case of a giant PC in a 56‑year‑old male who presented to the Affiliated Tumor Hospital, Zhengzhou University (Zhengzhou, Henan, China) with a 10‑month history of exertional dyspnea, associated with mild dysphagia that had persisted for 3 months. The present study reviews the clinical situation, laboratory examination, radiographic findings, treatment and prognosis of the patient, and provides a brief discussion regarding the associated literature. Giant PCs may manifest with compressive symptoms of the surrounding tissues. The diagnosis of a giant PC is based on increased levels of PTH in the fluid collected during the aspiration of the cyst. Management by surgical excision is recommended for giant PCs that cause local cervical symptoms.

View Figures

View References

1	Sandstrom I: Whether humans have multiple thyroid lobes? Ups Lakafor Forhandl. 14:441–471. 1880.(In Danish).
2	Goris D: Excise the third thyroid lobe. Ann Soc Belg Chir. 5:394–400. 1905.(In French).
3	Mostafapour SP, True L and Futran ND: Clinical problem solving: Pathology. Pathology quiz case: 1 Benign parathyroid cyst. Arch Otolaryngol Head Neck Surg. 128:592–594, 594. 2002. View Article : Google Scholar : PubMed/NCBI
4	Pinney SP and Daly PA: Parathyroid cyst: An uncommon cause of a palpable neck mass and hypercalcemia. West J Med. 170:118–120. 1999.PubMed/NCBI
5	Clark OH: Parathyroid cysts. Am J Surg. 135:395–402. 1978. View Article : Google Scholar : PubMed/NCBI
6	Rosenberg J, Orlando R III, Ludwig M and Pyrtek LJ: Parathyroid cysts. Am J Surg. 143:473–480. 1982. View Article : Google Scholar : PubMed/NCBI
7	Ramos-Gabatin A, Young RL and Schenk D: Parathyroid cyst: Medical diagnosis and therapy. South Med J. 75:1138–1140. 1982. View Article : Google Scholar : PubMed/NCBI
8	Sen P, Flower N, Papesch M, Davis A and Spedding AV: A benign parathyroid cyst presenting with hoarse voice. J Laryngol Otol. 114:147–148. 2000. View Article : Google Scholar : PubMed/NCBI
9	McCoy KL, Yim JH, Zuckerbraun BS, Ogilvie JB, Peel RL and Carty SE: Cystic parathyroid lesions: Functional and nonfunctional parathyroid cysts. Arch Surg. 144:52–56; discussion 56. 2009. View Article : Google Scholar : PubMed/NCBI
10	Cappelli C, Rotondi M, Pirola I, De Martino E, Leporati P, Magri F, Rosei EA, Chiovato L and Castellano M: Prevalence of parathyroid cysts by neck ultrasound scan in unselected patients. J Endocrinol Invest. 32:357–359. 2009. View Article : Google Scholar : PubMed/NCBI
11	McKay GD, Ng TH, Morgan GJ and Chen RC: Giant functioning parathyroid cyst presenting as a retrosternal goitre. ANZ J Surg. 77:297–304. 2007. View Article : Google Scholar : PubMed/NCBI
12	Rossi ED, Revelli L, Giustozzi E, Straccia P, Stigliano E, Lombardi CP, Pontecorvi A and Fadda G: Large non-functioning parathyroid cysts: Our institutional experience of a rare entity and a possible pitfall in thyroid cytology. Cytopathology. 26:114–121. 2015. View Article : Google Scholar : PubMed/NCBI
13	Fadda G and Rossi ED: Liquid-based cytology in fine-needle aspiration biopsies of the thyroid gland. Acta Cytol. 55:389–400. 2011. View Article : Google Scholar : PubMed/NCBI
14	Ihm PS, Dray T, Sofferman RA, Nathan M and Hardin NJ: Parathyroid cysts: Diagnosis and management. Laryngoscope. 111:1576–1578. 2001. View Article : Google Scholar : PubMed/NCBI
15	Pacini F, Antonelli A, Lari R, Gasperini L, Baschieri L and Pinchera A: Unsuspected parathyroid cysts diagnosed by measurement of thyroglobulin and parathyroid hormone concentrations in fluid aspirates. Ann Intern Med. 102:793–794. 1985. View Article : Google Scholar : PubMed/NCBI
16	Shi B, Guo H and Tang N: Treatment of parathyroid cysts with fine-needle aspiration. Ann Intern Med. 131:797–798. 1999. View Article : Google Scholar : PubMed/NCBI
17	Sung JY, Baek JH, Kim KS, Lee D, Ha EJ and Lee JH: Symptomatic nonfunctioning parathyroid cysts: Role of simple aspiration and ethanol ablation. Eur J Radiol. 82:316–320. 2013. View Article : Google Scholar : PubMed/NCBI
18	Ujiki MB, Nayar R, Sturgeon C and Angelos P: Parathyroid cyst: Often mistaken for a thyroid cyst. World J Surg. 31:60–64. 2007. View Article : Google Scholar : PubMed/NCBI
19	Shields TW and Immerman SC: Mediastinal parathyroid cysts revisited. Ann Thorac Surg. 67:581–590. 1999. View Article : Google Scholar : PubMed/NCBI