Adult dermatomyositis associated with benign ovarian teratoma: A case report

Yu,Xiaomin; Qin,Dongyan; Ma,Dehua; Yao,Qin

doi:10.3892/ol.2016.4251

April-2016 Volume 11 Issue 4

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April-2016 Volume 11 Issue 4

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Case Report

Adult dermatomyositis associated with benign ovarian teratoma: A case report

Authors:
- Xiaomin Yu
- Dongyan Qin
- Dehua Ma
- Qin Yao
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynaecology, Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China
Pages: 2611-2614
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Published online on: February 19, 2016

https://doi.org/10.3892/ol.2016.4251
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Abstract

A 27-year-old female patient presented with a 3‑month history of bilateral orbital and facial edema accompanied by skin erythema and heliotrope rash. The left lesion was more critical than the right. Limb muscles were occasionally sore. On physical examination, scattered hemorrhagic rashes were observed on the patient's face and neck. Upon laboratory testing, creatine kinase (CK) was markedly elevated at 1,543.2 U/l, while CK‑MB isoenzyme (27.4 U/l), α‑hydroxybutyric dehydrogenase (188.4 U/l) and aspartate aminotransferase (65.3 U/l) were marginally elevated. The patient was diagnosed with dermatomyositis due to the dermatological features and elevated CK. Cancer marker analysis revealed positivity for carbohydrate antigen 125 (68.15 U/ml). Magnetic resonance imaging revealed thickening of the soft tissue of the left eyelid; furthermore, concurrent long T1‑ and T2‑weighted signals (fat saturation) were compatible with inflammatory infiltration. Non‑enhanced computed tomography identified that the right accessory region (right ovary and fallopian tube) had a cystic mass with a significant fat component and thickening of the anterior uterine wall. Gynecological ultrasound findings indicated an ovarian teratoma (8.7x7.8x9.3 cm) and uterine myoma (3.6x3.1 cm). The patient's dermatological symptoms and laboratory results were significantly relieved one week after surgical removal of the teratoma with the aid of hydrocortisone, methylprednisolone and methotrexate therapy.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Adult dermatomyositis associated with benign ovarian teratoma: A case report

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