Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
April-2016 Volume 11 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2016 Volume 11 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report

  • Authors:
    • Min Chen
    • Lingdi Yin
    • Yuling Yao
    • Lei Wang
    • Guifang Xu
    • Xiaoqi Zhang
    • Ying Lv
    • Qi Sun
    • Xiangshan Fan
    • Xiaoping Zou
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu 210008, P.R. China, First School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China, Department of Pathology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu 210008, P.R. China
  • Pages: 2491-2496
    |
    Published online on: February 24, 2016
       https://doi.org/10.3892/ol.2016.4268
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Lymphoepithelioma-like gastric carcinoma (LELGC) is a rare neoplasm of the stomach that accounts for 1-4% of all gastric cancer cases. It is characterized by the presence of a lymphoid stroma with cells arranged primarily in micro alveolar, thin trabecular and primitive tubular patterns or isolated cells. In the present study, the case of a 50-year-old male patient with LELGC and rectal laterally spreading tumor is presented. Following endoscopic submucosal dissection, a diagnosis of carcinoma was reached and the patient underwent total radical gastrectomy. The postoperative pathological stage was IA T1bN0cM0 according to the Tumor-Node-Metastasis classification of gastric carcinoma, and the patient recovered well. The present case is reported to summarize the endoscopic and pathological characteristics of LELGC.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Watanabe H, Enjoji M and Imai T: Gastric carcinoma with lymphoid stroma. Its morphologic characteristic and prognostic correlations. Cancer. 38:232–243. 1976. View Article : Google Scholar : PubMed/NCBI

2 

Gromski MA, Miller CA, Lee SH, Lee TH, Chung IK, Park SH, Kim SJ and Cho HD: Gastric lymphoepithelioma-like carcinoma mimicking a subepithelial lesion treated by endoscopic submucosal dissection. Gastrointest Endosc. 76:419–421. 2012. View Article : Google Scholar : PubMed/NCBI

3 

Shibata D, Tokunaga M, Uemura Y, Sato E, Tanaka S and Weiss LM: Association of Epstein-Barr virus with undifferentiated gastric carcinomas with intense lymphoid infiltration. Lymphoepithelioma-like carcinoma. Am J Pathol. 139:469–474. 1991.PubMed/NCBI

4 

van Beek J, zur Hausen A, Klein Kranenbarg E, van de Velde CJ, Middledorp JM, van den Brule AJ, Meijer CJ and Bloemena E: EBV-positive gastric adenocarcinomas: A distinct clinicopathologic entity with a low frequency of lymph node involvement. J Clin Oncol. 22:664–670. 2004. View Article : Google Scholar : PubMed/NCBI

5 

Shibata D and Weiss LM: Epstein-Barr virus-associated gastric adenocarcinoma. Am J Pathol. 140:769–794. 1992.PubMed/NCBI

6 

Lee JY, Kim KM, Min BH, Lee JH, Rhee PL and Kim JJ: Epstein-Barr virus-associated lymphoepithelioma-like early gastric carcinomas and endoscopic submucosal dissection: Case series. World J Gastroenterol. 20:1365–1370. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Grogg KL, Lohse CM, Pankratz VS, Halling KC and Smyrk TC: Lymphocyte-rich gastric cancer: Associations with Epstein-Barr virus, microsatellite instability, histology and survival. Mod Pathol. 16:641–651. 2003. View Article : Google Scholar : PubMed/NCBI

8 

Song HJ, Srivastava A, Lee J, Kim YS, Kim KM, Kang Ki W, Kim M and Kim S, Park CK and Kim S: Host inflammatory resoponse predicts survival of patients with Epstein-Barr virus-associated gastric carcinoma. Gastroenterology. 139:84–92. 2010. View Article : Google Scholar : PubMed/NCBI

9 

Herath CH and Chetty R: Epstein-Barr virus-associated lymphoepithelioma-like gastric carcinoma. Arch Pathol Lab Med. 132:706–709. 2008.PubMed/NCBI

10 

Ajani J, D'Amico TA, Hayman JA, Meropol NJ and Minsky B: National Comprehensive Cancer Network: Gastric cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw. 1:28–39. 2003.PubMed/NCBI

11 

Cheng N, Hui DY, Liu Y, Zhang NN, Jiang Y, Han J, Li HG, Ding YG, Du H, Chen JN and Shao CK: Is gastric lymphoepithelioma-like carcinoma as a special subtype of EBV-associated gastric carcinoma? New insight based on clinicopathological features and EBV genoma polymorphisms. Gastric Cancer. 18:246–255. 2015. View Article : Google Scholar : PubMed/NCBI

12 

Moore OS Jr and Foote FW Jr: The relatively favorable prognosis of medullary carcinoma of the breast. Cancer. 2:635–642. 1949. View Article : Google Scholar : PubMed/NCBI

13 

Fenoglio-Preiser C, Carneiro F, Correa P, Guilford P, Lambert R and Megraud F: Gastric carcinoma. World Health Organization Classification of Tumours - Pathology and Genetics of Tumours of the Digestive System. Hamilton SR and Aaltonen LA: IARC Press. (Lyon, France). 37–52. 2000.

14 

Takahashi T, Otani Y, Yoshida M, Furukawa T, Kameyama K, Akiba Y, Saikawa Y, Kubota T, Kumai K, Kuramochi S, et al: Gastric cancer mimicking a submucosal tumor diagnosed by laparoscopic excision biopsy. J Laparoendosc Adv Surg Tech A. 15:51–56. 2005. View Article : Google Scholar : PubMed/NCBI

15 

Beghelli S, de Manzoni G, Barbi S, Tomezzoli A, Roviello F, Di Gregorio C, Vindigni C, Bortesi L, Parisi A, Saragoni L, et al: Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers. Surgery. 139:347–356. 2006. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Chen M, Yin L, Yao Y, Wang L, Xu G, Zhang X, Lv Y, Sun Q, Fan X, Zou X, Zou X, et al: Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report. Oncol Lett 11: 2491-2496, 2016.
APA
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X. ... Zou, X. (2016). Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report. Oncology Letters, 11, 2491-2496. https://doi.org/10.3892/ol.2016.4268
MLA
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X., Lv, Y., Sun, Q., Fan, X., Zou, X."Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report". Oncology Letters 11.4 (2016): 2491-2496.
Chicago
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X., Lv, Y., Sun, Q., Fan, X., Zou, X."Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report". Oncology Letters 11, no. 4 (2016): 2491-2496. https://doi.org/10.3892/ol.2016.4268
Copy and paste a formatted citation
x
Spandidos Publications style
Chen M, Yin L, Yao Y, Wang L, Xu G, Zhang X, Lv Y, Sun Q, Fan X, Zou X, Zou X, et al: Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report. Oncol Lett 11: 2491-2496, 2016.
APA
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X. ... Zou, X. (2016). Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report. Oncology Letters, 11, 2491-2496. https://doi.org/10.3892/ol.2016.4268
MLA
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X., Lv, Y., Sun, Q., Fan, X., Zou, X."Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report". Oncology Letters 11.4 (2016): 2491-2496.
Chicago
Chen, M., Yin, L., Yao, Y., Wang, L., Xu, G., Zhang, X., Lv, Y., Sun, Q., Fan, X., Zou, X."Lymphoepithelioma-like gastric carcinoma in a patient with rectal laterally spreading tumor: A case report". Oncology Letters 11, no. 4 (2016): 2491-2496. https://doi.org/10.3892/ol.2016.4268
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team