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Case Report Open Access

Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review

  • Authors:
    • Tulay Kus
    • Gokmen Aktas
    • Mehmet Emin Kalender
    • Ibrahim Sari
    • Esra Ulker
    • Celaletdin Camci
  • View Affiliations / Copyright

    Affiliations: Division of Medical Oncology, Faculty of Medicine, Gaziantep University, Gaziantep, Anatolia 27310, Turkey, Division of Pathology, Faculty of Medicine, Gaziantep University, Gaziantep, Anatolia 27310, Turkey, Division of Internal Medicine, Faculty of Medicine, Gaziantep University, Gaziantep, Anatolia 27310, Turkey
    Copyright: © Kus et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2801-2805
    |
    Published online on: March 8, 2016
       https://doi.org/10.3892/ol.2016.4310
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Abstract

The present study reports the case of a collision tumor consisting of follicular lymphoma (FL) and adenocarcinoma in the cecum of a 73-year-old man. To the best of our knowledge, the present study is the 11th case of a collision tumor consisting of colon adenocarcinoma and lymphoma to be reported in the literature, and the first case of cecum adenocarcinoma with low grade FL in the same segment of the cecum and the same regional lymph node to be reported. The present study reviewed the literature to determine treatment options for patients with collision tumors. The present patient was administered with adjuvant chemotherapy for T3N1M0 colon cancer following surgery, due to the dominance of colon adenocarcinoma in the collision tumor. Following the completion of treatment, progression of the untreated FL was observed. In the literature, patients with collision tumors are administered with chemotherapy for stage IV FL, and following the completion of treatment patients have presented with a recurrence of early stage colon adenocarcinoma. The recommended treatment for collision tumors is dependent on the dominant tumor; however, the treatment options for collision tumors in the literature appeared to exacerbate the other tumor. The characteristics of the tumors altered following chemotherapy, and immunological alterations in the tumors due to chemotherapy appear to have contributed to the exacerbation of the tumors. Therefore, patients with early‑stage tumors should be considered at risk of recurrence of other malignancies, which are present in collision tumors.
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1 

Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, et al: SEER Cancer Statistics Review (CSR) 1975–2012. National Cancer Institute. Bethesda, MD: 2015.http://seer.cancer.gov/csr/1975_2012/Accessed. January 15–2016

2 

She WH, Day W, Lau PY, Mak KL and Yip AW: Primary colorectal lymphoma: Case series and literature review. Asian J Surg. 34:111–114. 2011. View Article : Google Scholar : PubMed/NCBI

3 

Tevlin R, Larkin JO, Hyland JM, O'Connell PR and Winter DC: Primary colorectal lymphoma - A single centre experience. Surgeon. 13:151–155. 2015. View Article : Google Scholar : PubMed/NCBI

4 

Saber MM, Zeeneldin AA, Samra MA and Farag SA: Primary gastrointestinal lymphoma in an Egyptian district: A study using a population-based cancer registry. J Egypt Natl Canc Inst. 25:95–101. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Rodríguez-Abreu D, Llanos Muñoz M, Provencio Pulla M, Rueda Domínguez A and Isla Casado D: SEOM (Spanish Society for Medical Oncology): SEOM clinical guidelines for the treatment of follicular non-Hodgkin's lymphoma. Clin Transl Oncol. 12:760–764. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Cornes JS: Multiple primary cancers: Primary malignant lymphomas and carcinomas of the intestinal tract in the same patient. J Clin Pathol. 13:483–489. 1960. View Article : Google Scholar : PubMed/NCBI

7 

Chazouillères O, Andréani T, Boucher JP, Calmus Y, de Sigalony H, Nordlinger R and Poupon R: Rectal adenocarcinoma in association with lymphoma (“collision tumor”). Gastroenterol Clin Biol. 14:185–186. 1990.(In French). PubMed/NCBI

8 

Mannweiler S, Dinges HP, Beham-Schmid C, Hauser H, Starlinger M and Regauer S: Colliding / concomitant tumors of the intestine: Report of 3 cases. Pathol Oncol Res. 9:188–192. 2003. View Article : Google Scholar : PubMed/NCBI

9 

Eshra A, Al-Hendal A, Al Enezi M, Al-Mishaan M and Dief Abo W: One patient, two lymphomas, three primaries. Gulf J Oncolog. 1:39–43. 2010.

10 

Sasaki S, Hatanaka K, Sahara N, Uekusa T, Hirayama K, Shirahata A and Ishimaru M: Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon: Report of a case. Surg Today. 40:975–981. 2010. View Article : Google Scholar : PubMed/NCBI

11 

Lin HH, Jiang JK and Lin JK: Collision tumor of low-grade B-cell lymphoma and adenocarcinoma with tuberculosis in the colon: A case report and literature review. World J Surg Oncol. 12:1472014. View Article : Google Scholar : PubMed/NCBI

12 

Chang H, Chuang WY, Shih LY and Tang TC: Collision in the colon: Concurrent adenocarcinoma and diffuse large B-cell lymphoma in the same tumour. Acta Clin Belg. 66:302–304. 2011.PubMed/NCBI

13 

Upadhyay R, Hammerich L, Peng P, Brown B, Merad M and Brody JD: Lymphoma: Immune evasion strategies. Cancers (Basel). 30:736–762. 2015. View Article : Google Scholar

14 

Kamel OW, van de Rijn M, Hanasono MM and Warnke RA: Immunosuppression-associated lymphoproliferative disorders in rheumatic patients. Leuk Lymphoma. 16:363–368. 1995. View Article : Google Scholar : PubMed/NCBI

15 

Mishra S, Malhotra P, Gupta AK, Singh PK, Javed S and Kumar R: A semiquinone glucoside derivative isolated from Bacillus sp. INM-1 provides protection against 5-fluorouracil-induced immunotoxicity. J Immunotoxicol. 12:56–63. 2015. View Article : Google Scholar : PubMed/NCBI

16 

Edge S, Byrd DR, Compton CC, Fritz AG, Greene FL and Trotti A: American Joint Committee on Cancer (AJCC) Cancer Staging Manual (7th). Springer. New York, NY: 1432010.

17 

Rosenberg SA: Validity of the Ann Arbor staging classification for the non-Hodgkin's lymphomas. Cancer Treat Rep. 61:1023–1027. 1977.PubMed/NCBI

18 

Solal-Céligny P, Roy P, Colombat P, White J, Armitage JO, Arranz-Saez R, Au WY, Bellei M, Brice P, Caballero D, et al: Follicular lymphoma international prognostic index. Blood. 104:1258–1265. 2004. View Article : Google Scholar : PubMed/NCBI

19 

Sørensen JB, Klee M, Palshof T and Hansen HH: Performance status assessment in cancer patients. An inter-observer variability study. Br J Cancer. 67:773–775. 1993. View Article : Google Scholar : PubMed/NCBI

20 

Chihara D, Ito H, Matsuda T, Shibata A, Katsumi A, Nakamura S, Tomotaka S, Morton LM, Weisenburger DD and Matsuo K: Differences in incidence and trends of haematological malignancies in Japan and the United States. Br J Haematol. 164:536–545. 2014. View Article : Google Scholar : PubMed/NCBI

21 

No authors listed: Aclinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project. Blood. 89:3909–3918. 1997.PubMed/NCBI

22 

Armitage JO and Weisenburger DD: New approach to classifying non-Hodgkin's lymphomas: Clinical features of the major histologic subtypes. Non-Hodgkin's Lymphoma Classification Project. J Clin Oncol. 16:2780–2795. 1998.PubMed/NCBI

23 

Montoto S and Fitzgibbon J: Transformation of indolent B-cell lymphomas. J Clin Oncol. 29:1827–1834. 2011. View Article : Google Scholar : PubMed/NCBI

24 

Cleary ML and Sklar J: Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci USA. 82:7439–7443. 1985. View Article : Google Scholar : PubMed/NCBI

25 

Campbell BA, Voss N, Woods R, Gascoyne RD, Morris J, Pickles T, Connors JM and Savage KJ: Long-term outcomes for patients with limited stage follicular lymphoma: Involved regional radiotherapy versus involved node radiotherapy. Cancer. 116:3797–3806. 2010. View Article : Google Scholar : PubMed/NCBI

26 

Friedberg JW, Byrtek M, Link BK, Flowers C, Taylor M, Hainsworth J, Cerhan JR, Zelenetz AD, Hirata J and Miller TP: Effectiveness of first-line management strategies for stage I follicular lymphoma: Analysis of the National LymphoCare Study. J Clin Oncol. 30:3368–3375. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Disis ML: Immune regulation of cancer. J Clin Oncol. 28:4531–4538. 2010. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Kus T, Aktas G, Kalender ME, Sari I, Ulker E and Camci C: Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review. Oncol Lett 11: 2801-2805, 2016.
APA
Kus, T., Aktas, G., Kalender, M.E., Sari, I., Ulker, E., & Camci, C. (2016). Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review. Oncology Letters, 11, 2801-2805. https://doi.org/10.3892/ol.2016.4310
MLA
Kus, T., Aktas, G., Kalender, M. E., Sari, I., Ulker, E., Camci, C."Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review". Oncology Letters 11.4 (2016): 2801-2805.
Chicago
Kus, T., Aktas, G., Kalender, M. E., Sari, I., Ulker, E., Camci, C."Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review". Oncology Letters 11, no. 4 (2016): 2801-2805. https://doi.org/10.3892/ol.2016.4310
Copy and paste a formatted citation
x
Spandidos Publications style
Kus T, Aktas G, Kalender ME, Sari I, Ulker E and Camci C: Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review. Oncol Lett 11: 2801-2805, 2016.
APA
Kus, T., Aktas, G., Kalender, M.E., Sari, I., Ulker, E., & Camci, C. (2016). Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review. Oncology Letters, 11, 2801-2805. https://doi.org/10.3892/ol.2016.4310
MLA
Kus, T., Aktas, G., Kalender, M. E., Sari, I., Ulker, E., Camci, C."Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review". Oncology Letters 11.4 (2016): 2801-2805.
Chicago
Kus, T., Aktas, G., Kalender, M. E., Sari, I., Ulker, E., Camci, C."Collision tumor consisting of primary follicular lymphoma and adenocarcinoma in the cecum: A case report and literature review". Oncology Letters 11, no. 4 (2016): 2801-2805. https://doi.org/10.3892/ol.2016.4310
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