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Case Report

Primary extragastrointestinal stromal tumor of the pleura: A case report

  • Authors:
    • Cai‑Qing Zhang
    • De‑Gan Lu
    • Qing‑Fa Liu
    • Wei Xiao
  • View Affiliations / Copyright

    Affiliations: Department of Respiratory Medicine, Shandong Provincial Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, P.R. China, Department of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China
  • Pages: 3135-3138
    |
    Published online on: March 17, 2016
       https://doi.org/10.3892/ol.2016.4344
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Abstract

Gastrointestinal stromal tumors (GISTs) are the most common type of mesenchymal tumor of the gastrointestinal tract. The stomach and small intestine are the most common sites of occurrence. GISTs are mesenchymal neoplasms originating from the interstitial cells of Cajal (ICCs), and are characterized by positivity for cluster of differentiation (CD) 117, also known as proto‑oncogene c‑Kit. While the majority of GISTs develop in the alimentary tract, in rare cases they may also be found in extragastrointestinal tissues. This type of GIST is known as an extragastrointestinal stromal tumor (EGIST). Despite the fact that EGISTs have been reported in the mesentery, omentum and retroperitoneum, primary intrathoracic EGISTs, arising from the pleura or lungs, are rare. The patient presented in the current study was a 40-year-old man, who presented with a cough and pyrexia, with pleural effusion on the left side. Multiple nodules throughout the parietal pleura were identified by thoracoscopy and a diagnosis of primary GIST of pleura was established, since they were positive for CD117 and discovered on GIST‑1 and there was no evidence of gastrointestinal tumors. Subsequently, the patient was administered with imatinib and had no signs of disease recurrence 2 years later.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang CQ, Lu DG, Liu QF and Xiao W: Primary extragastrointestinal stromal tumor of the pleura: A case report. Oncol Lett 11: 3135-3138, 2016.
APA
Zhang, C., Lu, D., Liu, Q., & Xiao, W. (2016). Primary extragastrointestinal stromal tumor of the pleura: A case report. Oncology Letters, 11, 3135-3138. https://doi.org/10.3892/ol.2016.4344
MLA
Zhang, C., Lu, D., Liu, Q., Xiao, W."Primary extragastrointestinal stromal tumor of the pleura: A case report". Oncology Letters 11.5 (2016): 3135-3138.
Chicago
Zhang, C., Lu, D., Liu, Q., Xiao, W."Primary extragastrointestinal stromal tumor of the pleura: A case report". Oncology Letters 11, no. 5 (2016): 3135-3138. https://doi.org/10.3892/ol.2016.4344
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang CQ, Lu DG, Liu QF and Xiao W: Primary extragastrointestinal stromal tumor of the pleura: A case report. Oncol Lett 11: 3135-3138, 2016.
APA
Zhang, C., Lu, D., Liu, Q., & Xiao, W. (2016). Primary extragastrointestinal stromal tumor of the pleura: A case report. Oncology Letters, 11, 3135-3138. https://doi.org/10.3892/ol.2016.4344
MLA
Zhang, C., Lu, D., Liu, Q., Xiao, W."Primary extragastrointestinal stromal tumor of the pleura: A case report". Oncology Letters 11.5 (2016): 3135-3138.
Chicago
Zhang, C., Lu, D., Liu, Q., Xiao, W."Primary extragastrointestinal stromal tumor of the pleura: A case report". Oncology Letters 11, no. 5 (2016): 3135-3138. https://doi.org/10.3892/ol.2016.4344
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