Laparoscopic resection of benign schwannoma in the hepatoduodenal ligament: A case report and review of the literature

Tao,Liang; Xu,Shaoyan; Ren,Zhigang; Lu,Yiting; Kong,Xiaowu; Weng,Xiaohui; Xie,Zhijie; Hu,Zhiming

doi:10.3892/ol.2016.4410

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Case Report Open Access

Laparoscopic resection of benign schwannoma in the hepatoduodenal ligament: A case report and review of the literature

Authors:
- Liang Tao
- Shaoyan Xu
- Zhigang Ren
- Yiting Lu
- Xiaowu Kong
- Xiaohui Weng
- Zhijie Xie
- Zhiming Hu
View Affiliations / Copyright

Affiliations: Department of General Surgery, The Third People's Hospital of Haining, Jiaxing, Zhejiang 314408, P.R. China, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China, Department of Hepatobiliary and Pancreatic Surgery, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China

Copyright: © Tao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 3349-3353
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Published online on: April 5, 2016

https://doi.org/10.3892/ol.2016.4410
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Abstract

Schwannomas are mesenchymal neoplasms with a low malignant potential, which arise from Schwann cells. The tumors can occur in most parts of the body; however, the head, neck and flexor surfaces of the extremities are the most common locations. Schwannomas occurring in the hepatoduodenal ligament are extremely rare. To the best of our knowledge, only two cases of schwannoma in the hepatoduodenal ligament have been reported in the literature, and treatment of such cases by laparoscopic surgery has not yet been reported. The present study reports a case of schwannoma in the hepatoduodenal ligament in a 50‑year‑old male patient. Physical and laboratory examinations showed no abnormal results. Ultrasound and computed tomography failed to definitively diagnose the mass and identify its location. During laparoscopic surgery, a mass was identified in the hepatoduodenal ligament and was completely removed. The gross specimen was a 4.5x2.5x2.5‑cm localized mass, yellowish‑white in color. Microscopic examination revealed that the tumor was mainly composed of spindle‑shaped cells and no atypical cells were identified. Immunohistochemical staining showed a strong positive S‑100 protein reaction, whereas cluster of differentiation 34 and epithelial membrane antigen were negative. The final diagnosis of the lesion was benign schwannoma of the hepatoduodenal ligament. The patient was followed‑up for 7 months and, at the time of writing, was healthy and without any complications. The aim of the present study was to describe a rare case of hepatoduodenal ligament schwannoma in a 50-year-old male patient, and present a review of the literature. To the best of our knowledge, this is the first case of hepatoduodenal ligament schwannoma treated by laparoscopic surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Laparoscopic resection of benign schwannoma in the hepatoduodenal ligament: A case report and review of the literature

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