Web-based tools for microRNAs involved in human cancer (Review)

  • Authors:
    • Fermín Mar‑Aguilar
    • Cristina Rodríguez‑Padilla
    • Diana Reséndez‑Pérez
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  • Published online on: April 18, 2016     https://doi.org/10.3892/ol.2016.4446
  • Pages: 3563-3570
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Abstract

MicroRNAs (miRNAs/miRs) are a family of small, endogenous and evolutionarily-conserved non‑coding RNAs that are involved in the regulation of several cellular and functional processes. miRNAs can act as oncogenes or tumor suppressors in all types of cancer, and could be used as prognostic and diagnostic biomarkers. Databases and computational algorithms are behind the majority of the research performed on miRNAs. These tools assemble and curate the relevant information on miRNAs and present it in a user‑friendly manner. The current review presents 14 online databases that address every aspect of miRNA cancer research. Certain databases focus on miRNAs and a particular type of cancer, while others analyze the behavior of miRNAs in different malignancies at the same time. Additional databases allow researchers to search for mutations in miRNAs or their targets, and to review the naming history of a particular miRNA. All these databases are open‑access, and are a valuable tool for those researchers working with these molecules, particularly those who lack access to an advanced computational infrastructure.
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June-2016
Volume 11 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Mar‑Aguilar F, Rodríguez‑Padilla C and Reséndez‑Pérez D: Web-based tools for microRNAs involved in human cancer (Review). Oncol Lett 11: 3563-3570, 2016
APA
Mar‑Aguilar, F., Rodríguez‑Padilla, C., & Reséndez‑Pérez, D. (2016). Web-based tools for microRNAs involved in human cancer (Review). Oncology Letters, 11, 3563-3570. https://doi.org/10.3892/ol.2016.4446
MLA
Mar‑Aguilar, F., Rodríguez‑Padilla, C., Reséndez‑Pérez, D."Web-based tools for microRNAs involved in human cancer (Review)". Oncology Letters 11.6 (2016): 3563-3570.
Chicago
Mar‑Aguilar, F., Rodríguez‑Padilla, C., Reséndez‑Pérez, D."Web-based tools for microRNAs involved in human cancer (Review)". Oncology Letters 11, no. 6 (2016): 3563-3570. https://doi.org/10.3892/ol.2016.4446