Choriocarcinoma of unknown origin with multiple organ metastasis and cerebral hemorrhage: A case report and literature review

Wei,Hongtao; Zhang,Tianpeng; Liu,Bing; Xue,Xiaowei; Wang,Guoxing

doi:10.3892/ol.2016.4463

June-2016 Volume 11 Issue 6

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June-2016 Volume 11 Issue 6

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Case Report

Choriocarcinoma of unknown origin with multiple organ metastasis and cerebral hemorrhage: A case report and literature review

Authors:
- Hongtao Wei
- Tianpeng Zhang
- Bing Liu
- Xiaowei Xue
- Guoxing Wang
View Affiliations / Copyright

Affiliations: Department of Emergency, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China, Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, P.R. China
Pages: 3749-3752
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Published online on: April 19, 2016

https://doi.org/10.3892/ol.2016.4463
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Abstract

A 26-year-old man was admitted to Beijing Friendship Hospital, Capital Medical University (Beijing, China) with a 4‑day history of headache, moderate fever and numbness in the right upper limb. Prior to this, the patient had been diagnosed with cerebral hemorrhage by computed tomography (CT) scan upon visiting a local hospital. Chest X‑ray revealed multiple lesions in the lungs. Following referral, no abnormalities were found elsewhere, including in the testes, during a physical examination. Additional examination of other tumor biomarkers was unremarkable, and the initial suspicion of parasitic infection was ruled out. Tests revealed extremely high levels of β‑human chorionic gonadotropin (>200,000 mIU/ml). In addition, CT scans showed multiple metastases in the head, lungs, liver and kidneys. An ultrasound‑guided Tru‑Cut biopsy of the liver was performed in order to form a definitive diagnosis. Although the patient was treated with mannitol to reduce intracranial pressure, and with cefoperazone sodium and sulbactam sodium to fight infection, the patient succumbed to a cerebral hernia on the fourth day of hospitalization. Following this, the ultrasound‑guided Tru-Cut liver biopsy result was received, which suggested a diagnosis of choriocarcinoma.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Choriocarcinoma of unknown origin with multiple organ metastasis and cerebral hemorrhage: A case report and literature review

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