A retrospective study of six patients with mandibular metastatic carcinoma

Cai,Zhen; Zhu,Chao; Wang,Lizhen; Zhu,Ling; Zhang,Zhiyuan; Zhu,Hanguang; Wang,Yan'an

doi:10.3892/ol.2016.4484

A retrospective study of six patients with mandibular metastatic carcinoma

Authors:
- Zhen Cai
- Chao Zhu
- Lizhen Wang
- Ling Zhu
- Zhiyuan Zhang
- Hanguang Zhu
- Yan'an Wang
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Affiliations: Department of Oral and Maxillofacial Surgery, Linyi People's Hospital, Linyi, Shandong 276003, P.R. China, Department of Oral Pathology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China, Department of Radiology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China, Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, P.R. China
Published online on: April 20, 2016 https://doi.org/10.3892/ol.2016.4484
Pages: 3650-3654
Copyright: © Cai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Mandibular metastatic carcinoma is a rare lesion that accounts for <1% of all oral malignancies. To provide greater experience in this field, the present study was conducted in which 6 cases of mandibular metastatic carcinoma were retrospectively reviewed. The origin of the lesions was the prostate in 2 cases, the lungs in 2 cases, the breast in 1 case and the thyroid gland in 1 case. The clinical and computed tomography features, surgical management and follow‑up outcomes were investigated. The study indicated that surgeons should include the suspicion of metastasis in the differential diagnosis for mandibular tumor, particularly in patients who have a history of malignancy. A poor prognosis was associated with the examined patients. To extend the survival time as long as possible, a treatment strategy using multiple therapies, including segmental mandibulectomy, radiotherapy and chemotherapy, is recommended.

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