Giant cell tumor of the patella with a secondary aneurysmal bone cyst: A case report

Song,Mingzhi; Dai,Wei; Sun,Ran; Liang,Hongfeng; Liu,Bingwu; Wu,Yuxuan; Ma,Kai; Lu,Ming

doi:10.3892/ol.2016.4540

Giant cell tumor of the patella with a secondary aneurysmal bone cyst: A case report

Authors:
- Mingzhi Song
- Wei Dai
- Ran Sun
- Hongfeng Liang
- Bingwu Liu
- Yuxuan Wu
- Kai Ma
- Ming Lu
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Affiliations: Department of Orthopedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China, Department of Nursing, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China, Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China
Published online on: May 6, 2016 https://doi.org/10.3892/ol.2016.4540
Pages: 4045-4048

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Abstract

The substance of the patella is an uncommon location for tumor occurrence and development. The present study reports a case of giant cell tumor (GCT) of the patella, combined with an aneurysmal bone cyst (ABC). To the best of our knowledge, this is the second report of GCT with ABC published in English. GCT is the most common type of benign tumor. Secondary ABC is frequently associated with GCT, but this symbiotic tumor rarely occurs in the patella. A 27‑year‑old male patient was examined at the outpatient clinic, and clinicopathological characteristics of the tumor were observed. X‑ray and computed tomography (CT) scans revealed a lytic lesion located in the center of the right patella. Curettage, followed by autogenic and allograft bone grafting, was performed. Histopathologically, the lesion was diagnosed as a GCT with secondary ABC. No recurrence or metastasis was identified during the 1‑year follow‑up period. The present study reports a case of GCT with secondary ABC, and discusses the rare location and histopathological type of this tumor, in order to improve diagnosis and treatment of patellar tumors in general.

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1	Mercuri M and Casadei R: Patellar tumors. Clin Orthop Relat Res. 389:35–46. 2001. View Article : Google Scholar : PubMed/NCBI
2	Murphey MD, Nomikos GC, Flemming DJ, Gannon FH, Temple HT and Kransdorf MJ: From the archives of AFIP. Imaging of giant cell tumor and giant cell reparative granuloma of bone: Radiologic-pathologic correlation. Radiographics. 21:1283–1309. 2001. View Article : Google Scholar : PubMed/NCBI
3	Locher GW and Kaiser G: Giant-cell tumors and aneurysmal bone cysts of ribs in childhood. J Pediatr Surg. 10:103–108. 1975. View Article : Google Scholar : PubMed/NCBI
4	Yale JF and Kaplan JA: Aneurysmal bone cyst arising from a giant cell tumor of the calcaneus. J Am Podiatr Med Assoc. 85:708–709. 1995. View Article : Google Scholar : PubMed/NCBI
5	Kinley S, Wiseman F and Wertheimer SJ: Giant cell tumor of the talus with secondary aneurysmal bone cyst. J Foot Ankle Surg. 32:38–46. 1993.PubMed/NCBI
6	Wu Z, Yang X, Xiao J, Feng D, Huang Q, Zheng W, Huang W and Zhou Z: Aneurysmal bone cyst secondary to giant cell tumor of the mobile spine: A report of 11 cases. Spine (Phila Pa 1976). 36:E1385–E1390. 2011. View Article : Google Scholar : PubMed/NCBI
7	Athanasian EA: Aneurysmal bone cyst and giant cell tumor of bone of the hand and distal radius. Hand Clin. 20:269–281. 2004. View Article : Google Scholar : PubMed/NCBI
8	Marudanayagam A and Gnanadoss JJ: Secondary aneurysmal bone cyst of the patella: A case report. Iowa Orthop J. 26:144–146. 2006.PubMed/NCBI
9	Hoch B, Inwards C, Sundaram M and Rosenberg AE: Multicentric giant cell tumor of bone. Clinicopathologic analysis of thirty cases. J Bone Joint Surg Am. 88:1998–2008. 2006. View Article : Google Scholar : PubMed/NCBI
10	Donthineni R, Boriani L, Ofluoglu O and Bandiera S: Metastatic behaviour of giant cell tumour of the spine. Int Orthop. 33:497–501. 2009. View Article : Google Scholar : PubMed/NCBI
11	Lewis VO, Wei A, Mendoza T, Primus F, Peabody T and Simon MA: Argon beam coagulation as an adjuvant for local control of giant cell tumor. Clin Orthop Relat Res. 454:192–197. 2007. View Article : Google Scholar : PubMed/NCBI
12	Sung HW, Kuo DP, Shu WP, Chai YB, Liu CC and Li SM: Giant-cell tumor of bone: Analysis of two hundred and eight cases in Chinese patients. J Bone Joint Surg Am. 64:755–761. 1982.PubMed/NCBI
13	Steensma MR, Tyler WK, Shaber AG, Goldring SR, Ross FP, Williams BO, Healey JH and Purdue PE: Targeting the giant cell tumor stromal cell: Functional characterization and a novel therapeutic strategy. PLoS One. 8:e691012013. View Article : Google Scholar : PubMed/NCBI
14	Compere EL: The diagnosis and treatment of giant cell tumors of bone. J Bone Joint Surg Am. 35:822–830. 1953.PubMed/NCBI
15	Goldenberg RR, Campbell CJ and Bonfiglio M: Giant cell tumor of bone. An analysis of two hundred and eighteen cases. J Bone Joint Surg Am. 52:619–664. 1970.PubMed/NCBI
16	Song M, Zhang Z, Wu Y, Ma K and Lu M: Primary tumors of the patella. World J Surg Oncol. 13:1632015. View Article : Google Scholar : PubMed/NCBI
17	Casadei R, Kreshak J, Rinaldi R, Rimondi E, Bianchi G, Alberghini M, Ruggieri P and Vanel D: Imaging tumors of the patella. Eur J Radiol. 82:2140–2148. 2013. View Article : Google Scholar : PubMed/NCBI
18	Amanatullah DF, Clark TR, Lopez MJ, Borys D and Tamurian RM: Giant cell tumor of bone. Orthopedics. 37:112–120. 2014. View Article : Google Scholar : PubMed/NCBI
19	Rădulescu R, Bădilă A, Manolescu R, Sajin M and Japie I: Aneurysmal bone cyst - clinical and morphological aspects. Rom J Morphol Embryol. 55:977–981. 2014.PubMed/NCBI
20	Whitmore A: Aneurysmal bone cysts. JAAPA. 26:56–57. 2013.PubMed/NCBI
21	Casadei R, Ruggieri P, Moscato M, Ferraro A and Picci P: Aneurysmal bone cyst and giant cell tumor of the foot. Foot Ankle Int. 17:487–495. 1996. View Article : Google Scholar : PubMed/NCBI
22	Fletcher CD, Unni KK and Mertens F: World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. (Lyon, France). 247–251. 2002.
23	Tomasik P, Spindel J, Miszczyk L, Chrobok A, Koczy B, Widuchowski J, Mrozek T, Matysiakiewicz J and Pilecki B: Treatment and differential diagnosis of aneurysmal bone cyst based on our own experience. Ortop Traumatol Rehabil. 11:467–475. 2009.(In English and Polish). PubMed/NCBI