Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report

  • Authors:
    • Yajuan Qiu
    • Dandan Zhang
    • Mingzhi Zhang
  • View Affiliations

  • Published online on: May 26, 2016     https://doi.org/10.3892/ol.2016.4635
  • Pages: 611-614
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Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is an indolent cutaneous T-cell lymphoma with a favourable prognosis. The reported incidence of central nervous system (CNS) involvement in SPTCL is extremely low. SPTCL with CNS involvement is a fatal disease with no optimal treatment. The present study presents the case of a 27‑year‑old man who initially presented with erythematous nodules on the left buttock and left inguinal lymph node enlargement. A skin biopsy resulted in a diagnosis of SPTCL. Subsequent to diagnosis, the patient developed CNS involvement and underwent treatment of fotemustine, teniposide and dexamethasone, and complete remission was achieved for 78 months. To the best of our knowledge, this is the first case report of secondary CNS SPTCL with long‑term remission. Accumulating evidence shows that this CNS‑directed regimen can be effective in SPTCL with CNS involvement and in other CNS lymphomas.
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July-2016
Volume 12 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Qiu Y, Zhang D and Zhang M: Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report. Oncol Lett 12: 611-614, 2016
APA
Qiu, Y., Zhang, D., & Zhang, M. (2016). Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report. Oncology Letters, 12, 611-614. https://doi.org/10.3892/ol.2016.4635
MLA
Qiu, Y., Zhang, D., Zhang, M."Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report". Oncology Letters 12.1 (2016): 611-614.
Chicago
Qiu, Y., Zhang, D., Zhang, M."Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report". Oncology Letters 12, no. 1 (2016): 611-614. https://doi.org/10.3892/ol.2016.4635