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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2016 Volume 12 Issue 1

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Oncogenic role of the Notch pathway in primary liver cancer (Review) Corrigendum in /10.3892/ol.2016.5145

Jie Lu, Yujing Xia, Kan Chen, Yuanyuan Zheng, Jianrong Wang, Wenxia Lu, Qin Yin, Fan Wang, Yingqun Zhou, Chuanyong Guo
Pages: 3-10
Published online on: 18 May 2016

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Review

Applications of nanoparticle drug delivery systems for the reversal of multidrug resistance in cancer (Review)

Yinghong Huang, Susan P.C. Cole, Tiange Cai, Yu Cai
Pages: 11-15
Published online on: 17 May 2016

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Article Open Access

Co‑existence of PHF6 and NOTCH1 mutations in adult T-cell acute lymphoblastic leukemia

Min Li, Lichan Xiao, Jingyan Xu, Run Zhang, Jingjing Guo, Justin Olson, Yujie Wu, Jianyong Li, Chunhua Song, Zheng Ge
Pages: 16-22
Published online on: 16 May 2016

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Article

Long form collapsin response mediator protein-1 promotes the migration and invasion of osteosarcoma cells

Huige Hou, Lin Chen, Zhengang Zha, Shaohui Cai, Minghui Tan, Guoqing Guo, Ning Liu, Guorong She, Songwei Xun
Pages: 23-28
Published online on: 13 May 2016

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Article Open Access

Therapeutic response to a novel enzyme-targeting radiosensitization treatment (Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas) in patients with recurrent breast cancer

Nobutaka Aoyama, Yasuhiro Ogawa, Miki Yasuoka, Masao Takahashi, Hitomi Iwasa, Kana Miyatake, Tomoaki Yamanishi, Norihiko Hamada, Taiji Tamura, Akihito Nishioka, Takuji Yamagami
Pages: 29-34
Published online on: 16 May 2016

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Article Open Access

Association between the CYP11 family and six cancer types

Ziwei Fan, Zhen Wang, Weiran Chen, Zhiwei Cao, Yixue Li
Pages: 35-40
Published online on: 13 May 2016

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Article Open Access

Biological characteristics of side population cells in a self-established human ovarian cancer cell line

Zhentong Wei, Shuang Lv, Yishu Wang, Meiyu Sun, Guangfan Chi, Jun Guo, Peiye Song, Xiaoyu Fu, Songling Zhang, Yulin Li
Pages: 41-48
Published online on: 13 May 2016

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Article Open Access

Inactivated Tianjin strain, a novel genotype of Sendai virus, induces apoptosis in HeLa, NCI-H446 and Hep3B cells

Jun Chen, Han Han, Bin Wang, Liying Shi
Pages: 49-56
Published online on: 13 May 2016

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Article Open Access

The antibacterial peptide from Bombyx mori cecropinXJ induced growth arrest and apoptosis in human hepatocellular carcinoma cells

Lijie Xia, Yanling Wu, Ji Ma, Jianhua Yang, Fuchun Zhang
Pages: 57-62
Published online on: 17 May 2016

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Article Open Access

Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway

Zhong‑Quan Zhao, Zhong‑Yang Yu, Jie Li, Xue‑Nong Ouyang
Pages: 63-68
Published online on: 18 May 2016

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Case Report Open Access

Paraneoplastic Cushing's syndrome associated with bronchopulmonary carcinoid tumor in youth: A case report and review of the literature

Wen‑Ya Li, Xu‑Dong Liu, Wei‑Nan Li, Si‑Yuan Dong, Xiao‑Han Qu, Shu‑Lei Gong, Ming‑Rui Shao, Lin Zhang
Pages: 69-72
Published online on: 16 May 2016

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Article Open Access

Identification of genes associated with renal cell carcinoma using gene expression profiling analysis

Ting Yao, Qinfu Wang, Wenyong Zhang, Aihong Bian, Jinping Zhang
Pages: 73-78
Published online on: 16 May 2016

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Article Open Access

Value of distinguishing differentiated thyroid carcinoma by miRNA

Jianlin Xu, Ding Zhang, Qian Niu, Yonggang Nan, Changbei Shi, Hua Zhao, Xiaoyan Liang
Pages: 79-82
Published online on: 12 May 2016

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Article Open Access

ImmunoCyt test compared to cytology in the diagnosis of bladder cancer: A meta-analysis

Houguang He, Conghui Han, Lin Hao, Guanghui Zang
Pages: 83-88
Published online on: 12 May 2016

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Article Open Access

Pioglitazone does not increase the risk of type II diabetes in patients with bladder cancer: A retrospective study

Youhong Dong, Anping Wang
Pages: 89-92
Published online on: 13 May 2016

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Article Open Access

Aspirin inhibits growth of ovarian cancer by upregulating caspase-3 and downregulating bcl-2 Retraction in /10.3892/ol.2019.10108

Lin Li, Xiaogang Mao, Xiaomin Qin, Min Zhou, Hui Xing, Fan Dong, Xiaoyuan Jiang, Wenhui Zhuang
Pages: 93-96
Published online on: 18 May 2016

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Article Open Access

miR-199a-5p induces cell invasion by suppressing E-cadherin expression in cutaneous squamous cell carcinoma

Shaohua Wang, Ke Cao, Quanyong He, Zhaoqi Yin, Jianda Zhou
Pages: 97-101
Published online on: 18 May 2016

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Article Open Access

Autophagy inhibition enhances colorectal cancer apoptosis induced by dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235

Xiaoyu Yang, Bingxuan Niu, Libo Wang, Meiling Chen, Xiaochun Kang, Luonan Wang, Yinghua Ji, Jiateng Zhong
Pages: 102-106
Published online on: 17 May 2016

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Article Open Access

Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways

Gesche Frohwitter, Horst Buerger, Paul J. van Diest, Eberhard Korsching, Johannes Kleinheinz, Thomas Fillies
Pages: 107-113
Published online on: 16 May 2016

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Article Open Access

Enhanced expression of early mitotic inhibitor‑1 predicts a poor prognosis in esophageal squamous cell carcinoma patients

Chengqi Guan, Jianfeng Zhang, Jianguo Zhang, Hui Shi, Runzhou Ni
Pages: 114-120
Published online on: 18 May 2016

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Case Report Open Access

Giant malignant phyllodes tumor of the breast: A rare case report and literature review

Min Liu, Shuo Yang, Bin Liu, Liang Guo, Xueying Bao, Bailong Liu, Lihua Dong
Pages: 121-124
Published online on: 16 May 2016

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Article Open Access

Specific protein 1 depletion attenuates glucose uptake and proliferation of human glioma cells by regulating GLUT3 expression

Chuanyi Zheng, Kun Yang, Maoying Zhang, Mingming Zou, Enqi Bai, Quanhong Ma, Ruxiang Xu
Pages: 125-131
Published online on: 17 May 2016

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Article Open Access

Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis Corrigendum in /10.3892/ol.2026.15832

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Pages: 132-138
Published online on: 16 May 2016

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Article Open Access

Delineating the effect of demethylating agent 5-aza-2'-deoxycytidine on human Caco-2 colonic carcinoma cells

Xiumei Li, Bingzhao Qin, Bo Liu
Pages: 139-143
Published online on: 09 May 2016

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Case Report Open Access

Spontaneous hematoma in the setting of dual anti-platelet therapy with ticagrelor: A case report

Chunguang Feng, Linguang Wang, Lulu Wang
Pages: 144-146
Published online on: 09 May 2016

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Article Open Access

Removal of craniopharyngioma via fronto-basal interhemispheric approach

Hongshun Xing, Hongbo Xing, Peiquan Hui, Bin Yang
Pages: 147-149
Published online on: 12 May 2016

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Article

A comparison of four methods for detecting KRAS mutations in formalin-fixed specimens from metastatic colorectal cancer patients

Mototsugu Matsunaga, Toshikado Kaneta, Keisuke Miwa, Wataru Ichikawa, Ken‑Ichi Fujita, Fumio Nagashima, Junji Furuse, Masayoshi Kage, Yoshito Akagi, Yasutsuna Sasaki
Pages: 150-156
Published online on: 16 May 2016

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Article

Integration and bioinformatics analysis of DNA‑methylated genes associated with drug resistance in ovarian cancer

Bingbing Yan, Fuqiang Yin, Qi Wang, Wei Zhang, Li Li
Pages: 157-166
Published online on: 18 May 2016

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Case Report

Simultaneous metastases of clear cell renal cell carcinoma to the urinary bladder and left retroperitoneal space: A case report and review of the literature

Hengping Li, Jianzhong Wang, Qiang Wei, Huan Wang
Pages: 167-170
Published online on: 16 May 2016

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Article

Human wings apart-like gene is specifically overexpressed in cervical cancer

Xiaoqin Lu, Jinquan Cui, Meizhou Fu, Wuliang Wang
Pages: 171-176
Published online on: 13 May 2016

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Article

Anticancer effect of arsenite on cell migration, cell cycle and apoptosis in human pancreatic cancer cells

Yohei Horibe, Seiji Adachi, Ichiro Yasuda, Takahiro Yamauchi, Junji Kawaguchi, Osamu Kozawa, Masahito Shimizu, Hisataka Moriwaki
Pages: 177-182
Published online on: 13 May 2016

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Article

Prospective evaluation of FISH for detecting upper tract urothelial carcinoma in voided urine specimens

Qiubo Yu, Yanan Li, Gang Li, Tinghong Li, Han Zeng, Zhu Yang, Deling Wang
Pages: 183-188
Published online on: 17 May 2016

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Case Report

Hepatoid adenocarcinoma of the lung without production of α-fetoprotein: A case report and review of the literature

Ji Ning Sun, Bao Long Zhang, Lin Kun Li, Hai Yan Yu, Bin Wang
Pages: 189-194
Published online on: 13 May 2016

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Case Report

Misdiagnosis of pathological femoral fracture in a patient with intramuscular hemangioma: A case report

Xiaolong Yu, Tao Nie, Bin Zhang, Min Dai, Hucheng Liu, Fan Zou
Pages: 195-198
Published online on: 18 May 2016

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Article

Low expression of secreted frizzled-related protein 2 and nuclear accumulation of β-catenin in aggressive nonfunctioning pituitary adenoma

Youtu Wu, Jiwei Bai, Linchuan Hong, Chunhui Liu, Shengyuan Yu, Guoqiang Yu, Yazhuo Zhang
Pages: 199-206
Published online on: 13 May 2016

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Article

Elovl6 is a poor prognostic predictor in breast cancer

Yin‑Hsun Feng, Wei‑Yu Chen, Yu‑Hsuan Kuo, Chao‑Ling Tung, Chao‑Jung Tsao, Ai‑Li Shiau, Chao‑Liang Wu
Pages: 207-212
Published online on: 16 May 2016

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Case Report

Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report

Sang Mi Chung, Seong Ji Choi, Min Jung Kim, Jung Yoon Choi, Hong Jun Kim, Suk‑Young Lee, Eun Joo Kang
Pages: 213-216
Published online on: 17 May 2016

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Article

Downregulation of SENP1 inhibits cell proliferation, migration and promotes apoptosis in human glioma cells

Qiu‑Sheng Zhang, Meng Zhang, Xian‑Jian Huang, Xiao‑Jia Liu, Wei‑Ping Li
Pages: 217-221
Published online on: 12 May 2016

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Article

Functional annotation of noncoding variants and prioritization of cancer-associated lncRNAs in lung cancer

Hua Li, Xin Lv
Pages: 222-230
Published online on: 18 May 2016

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Article

Effects of melatonin on HIF‑1α and VEGF expression and on the invasive properties of hepatocarcinoma cells

Jucimara Colombo, João Marcos Wolf Maciel, Lívia Carvalho Ferreira, Renato Ferreira Da Silva, Debora Aparecida Pires De Campos Zuccari
Pages: 231-237
Published online on: 18 May 2016

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Article

Multidetector computed tomography analysis of benign and malignant nodules in patients with chronic lymphocytic thyroiditis

Caisong Zhu, Wei Liu, Jun Yang, Jing Yang, Kangwei Shao, Lixin Yuan, Hairong Chen, Wei Lu, Ying Zhu
Pages: 238-242
Published online on: 16 May 2016

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Article

Expression and clinical significance of glucose transporter-1 in pancreatic cancer

Kai Lu, Jian Yang, De‑Chun Li, Song‑Bing He, Dong‑Ming Zhu, Li‑Feng Zhang, Xu Zhang, Xiao‑Chen Chen, Bing Zhang, Jian Zhou
Pages: 243-249
Published online on: 16 May 2016

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Article

Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation

Hyun Joo Jang, Eun Mi Hong, Se Woo Park, Hyun Woo Byun, Dong Hee Koh, Min Ho Choi, Sea Hyub Kae, Jin Lee
Pages: 250-256
Published online on: 13 May 2016

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Article

Synchronous ovarian metastasis from colorectal cancer: A report of two cases

Jiro Shimazaki, Takanobu Tabuchi, Kiyotaka Nishida, Akira Takemura, Gyo Motohashi, Hideki Kajiyama, Shuji Suzuki
Pages: 257-261
Published online on: 11 May 2016

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Article

Effect of therapy-related acute myeloid leukemia on the outcome of patients with acute myeloid leukemia

Ana Espírito Santo, Sérgio Chacim, Isabel Ferreira, Luís Leite, Claudia Moreira, Dulcineia Pereira, Margarida Dantas Brito, Marta Nunes, Nelson Domingues, Isabel Oliveira, Ilídia Moreira, Angelo Martins, Luísa Viterbo, José Mário Mariz, Rui Medeiros
Pages: 262-268
Published online on: 17 May 2016

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Article

Serum expression levels of microRNA-382‑3p, -598-3p, -1246 and -184 in breast cancer patients

Lun Fu, Zhaoyun Li, Jie Zhu, Pan Wang, Guangmin Fan, Yuechu Dai, Zhibao Zheng, Yang Liu
Pages: 269-274
Published online on: 16 May 2016

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Article

TLR7 Gln11Leu single nucleotide polymorphism and susceptibility to cutaneous melanoma

Lisa Elefanti, Giorgia Sacco, Camilla Stagni, Marco Rastrelli, Chiara Menin, Irene Russo, Mauro Alaibac
Pages: 275-280
Published online on: 16 May 2016

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Case Report

Isolated port-site metastasis after surgical staging for low-risk endometrioid endometrial cancer: A case report

Daniele Mautone, Andrea Dall'Asta, Michela Monica, Letizia Galli, Vito Andrea Capozzi, Federico Marchesi, Giovanna Giordano, Roberto Berretta
Pages: 281-284
Published online on: 17 May 2016

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Article

Promoter hypermethylation and downregulation of the FAS gene may be involved in colorectal carcinogenesis

Mehdi Manoochehri, Nasim Borhani, Ashraf Karbasi, Ameneh Koochaki, Bahram Kazemi
Pages: 285-290
Published online on: 16 May 2016

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Article

Renal oncocytoma: A report of two cases and review of the literature

Yuantao Wang, Yu Hu, Xiuyu Zhai, Weigang Wang, Biao Dong, Honglan Zhou
Pages: 291-294
Published online on: 17 May 2016

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Article

Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells

Chenghua Lou, Satoru Yokoyama, Sherif Abdelhamed, Ikuo Saiki, Yoshihiro Hayakawa
Pages: 295-300
Published online on: 11 May 2016

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Article

miR-154 inhibits migration and invasion of human non-small cell lung cancer by targeting ZEB2 Retraction in /10.3892/ol.2021.12873

Xingyu Lin, Zhiguang Yang, Peng Zhang, Yunpeng Liu, Guoguang Shao
Pages: 301-306
Published online on: 16 May 2016

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Article

xCT expression modulates cisplatin resistance in Tca8113 tongue carcinoma cells

Peng Zhang, Wei Wang, Zhenhui Wei, Li Xu, Xuanning Yang, Yuanhong Du
Pages: 307-314
Published online on: 16 May 2016

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Article

Hypoxia regulates the expression of tissue factor pathway signaling elements in a rat glioma model

Robson Q. Monteiro, Luize G. Lima, Nathália P. Gonçalves, Mayara R. Arruda De Souza, Ana C. Leal, Marcos A. Almeida Demasi, Mari C. Sogayar, Tatiana C. Carneiro‑Lobo
Pages: 315-322
Published online on: 17 May 2016

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Article

A novel combination treatment for breast cancer cells involving BAPTA-AM and proteasome inhibitor bortezomib

Azmi Yerlikaya, Elif Erdoğan, Emrah Okur, Şerife Yerlikaya, Bircan Savran
Pages: 323-330
Published online on: 17 May 2016

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Case Report

Enterovesical fistula caused by regressive change of non-Hodgkin's lymphoma: A case report

Yu‑Ting Lee, Ying‑Yuan Chen, Chia‑Yun Wu, Hung‑Ming Chen, Cheng‑Hwai Tzeng, Tzeon‑Jye Chiou
Pages: 331-333
Published online on: 13 May 2016

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Article

Resistance to chemotherapy is associated with altered glucose metabolism in acute myeloid leukemia

Kui Song, Min Li, Xiaojun Xu, Li Xuan, Guinian Huang, Qifa Liu
Pages: 334-342
Published online on: 17 May 2016

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Article

Gamma Knife radiosurgery combined with stereotactic aspiration as an effective treatment method for large cystic brain metastases

Hongwei Wang, Songtao Qi, Changwu Dou, Haitao Ju, Zhanbiao He, Qinghai Ma
Pages: 343-347
Published online on: 18 May 2016

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Case Report

Primary seminoma arising in the middle mediastinum: A case report

Jing Xu, Jinglan Zhao, Shaoqing Geng, Qi Wang, Pengfei Wang, Chunling Zhang, Xiongzeng Zhu, Youxin Ji
Pages: 348-350
Published online on: 16 May 2016

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Case Report

Oligodendroglioma metastasis to the bone marrow mimicking multiple myeloma: A case report

Yuan Jian, Wen Gao, Yin Wu, Yanchen Li, Yong Zhang, Guangzhong Yang, Wenming Chen
Pages: 351-355
Published online on: 13 May 2016

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Case Report

Bevacizumab to combat EGFR-TKI resistance in a patient with advanced non-small cell lung cancer harboring an EGFR mutation: A case report

Zhiyi Wang, Pu Zhou, Guanghui Li
Pages: 356-360
Published online on: 16 May 2016

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Review

Ambra1 in autophagy and apoptosis: Implications for cell survival and chemotherapy resistance (Review)

Wei‑Liang Sun
Pages: 367-374
Published online on: 30 May 2016

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Review

Power of PTEN/AKT: Molecular switch between tumor suppressors and oncogenes (Review)

Yingqiu Xie, Sanzhar Naizabekov, Zhanlin Chen, Tursonjan Tokay
Pages: 375-378
Published online on: 26 May 2016

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Review

Potential signaling pathway involved in sphingosine-1-phosphate-induced epithelial-mesenchymal transition in cancer (Review)

Ye Zeng, Xing‑Hong Yao, Zhi‑Ping Yan, Jing‑Xia Liu, Xiao‑Heng Liu
Pages: 379-382
Published online on: 01 June 2016

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Article Open Access

B7‑H3 protein expression in a murine model of osteosarcoma

Jia‑Li Zhao, Feng‑Li Chen, Quan Zhou, Wei Pan, Xin‑Hong Wang, Jin Xu, Shao‑Xian Zhang, Li Ni, Hui‑Lin Yang
Pages: 383-386
Published online on: 02 June 2016

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Article Open Access

Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma

Chie Ishikawa, Masachika Senba, Naoki Mori
Pages: 387-392
Published online on: 25 May 2016

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Article Open Access

Differential expression of mucins in Middle Eastern patients with colorectal cancer

Khayal Al‑Khayal, Maha Abdulla, Omar Al‑Obaid, Ahmad Zubaidi, Mansoor‑Ali Vaali‑Mohammed, Abdulmalik Alsheikh, Rehan Ahmad
Pages: 393-400
Published online on: 01 June 2016

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Case Report Open Access

Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature

Tsung‑Wei Liu, Shih‑Han Hung, Po‑Yueh Chen
Pages: 401-404
Published online on: 25 May 2016

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Article Open Access

Gene expression profiling analysis of ovarian cancer

Ji‑Gang Yin, Xian‑Ying Liu, Bin Wang, Dan‑Yang Wang, Man Wei, Hua Fang, Mei Xiang
Pages: 405-412
Published online on: 01 June 2016

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Article

Peroxiredoxin 1 has an anti-apoptotic role via apoptosis signal-regulating kinase 1 and p38 activation in mouse models with oral precancerous lesions

Jianfei Zhang, Xinying Jing, Wenwen Niu, Min Zhang, Lihua Ge, Congcong Miao, Xiaofei Tang
Pages: 413-420
Published online on: 01 June 2016

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Article Open Access

Investigating polymorphisms by bioinformatics is a potential cost‑effective method to screen for germline mutations in Chinese familial adenomatous polyposis patients

Jun Yang, Wei Qing Liu, Wen Liang Li, Cheng Chen, Zhu Zhu, Min Hong, Zhi Qiang Wang, Jian Dong
Pages: 421-428
Published online on: 30 May 2016

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Article Open Access

Role of IL-33 expression in oncogenesis and development of human hepatocellular carcinoma

Yan Yang, Jun‑Bin Wang, Yu‑Mei Li, Yu Zhao, Rui Wang, Qiong Wu, Rong‑Sheng Zheng, Yu‑Rong Ou
Pages: 429-436
Published online on: 25 May 2016

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Article Open Access

Serum- and glucocorticoid-regulated protein kinase 3 overexpression promotes tumor development and aggression in breast cancer cells

Xiaojie Sun, Xiucai Liu, Bo Liu, Shuyan Li, Dongmei Zhang, Hongyan Guo
Pages: 437-444
Published online on: 26 May 2016

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Article Open Access

Interleukin-33 in human gliomas: Expression and prognostic significance

Dorothee Gramatzki, Karl Frei, Gieri Cathomas, Holger Moch, Michael Weller, Kirsten Diana Mertz
Pages: 445-452
Published online on: 25 May 2016

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Article Open Access

Overexpression of PY1289‑HER3 in sporadic pulmonary carcinoid from patients bearing MEN1 gene variants

Rossano Lattanzio, Serena Veschi, Gitana Maria Aceto, Maria Cristina Curia, Alessandro Cama, Laura De Lellis, Fabiana Fantini, Domenico Angelucci, Stefano Iacobelli, Mauro Piantelli, Pasquale Battista
Pages: 453-458
Published online on: 01 June 2016

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Article Open Access

Effects of HCG on human epithelial ovarian cancer vasculogenic mimicry formation in vivo

Sainan Gao, Chao Fan, Hua Huang, Changlai Zhu, Min Su, Yuquan Zhang
Pages: 459-466
Published online on: 25 May 2016

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Article Open Access

Evaluation of the ‘Hedgehog’ signaling pathways in squamous and basal cell carcinomas of the eyelids and conjunctiva

Ali Riza Cenk Celebi, Hayyam Kiratli, Figen Soylemezoglu
Pages: 467-472
Published online on: 25 May 2016

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Article Open Access

Identification of key genes associated with cervical cancer by comprehensive analysis of transcriptome microarray and methylation microarray

Ming‑Yan Liu, Hong Zhang, Yuan‑Jing Hu, Yu‑Wei Chen, Xiao‑Nan Zhao
Pages: 473-478
Published online on: 01 June 2016

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Case Report Open Access

Late recurrence of a malignant hypoglycemia‑inducing pelvic solitary fibrous tumor secreting high‑molecular‑weight insulin‑like growth factor‑II: A case report with protein analysis

Hiroki Ishihara, Kenji Omae, Junpei Iizuka, Hirohito Kobayashi, Izumi Fukuda, Tsunenori Kondo, Naomi Hizuka, Yoji Nagashima, Kazunari Tanabe
Pages: 479-484
Published online on: 01 June 2016

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Article Open Access

Concomitant essential thrombocythemia with JAK2 V617F mutation in a patient with chronic myeloid leukemia with major molecular response with imatinib and long-term follow-up

Katia Borgia Barbosa Pagnano, Márcia Torresan Delamain, Mariana Munari Magnus, José Vassallo, Carmino Antonio De Souza, Daiane De Almeida, Irene Lorand‑Metze
Pages: 485-487
Published online on: 26 May 2016

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Article Open Access

miR-10b promotes invasion by targeting HOXD10 in colorectal cancer

Yunfeng Wang, Zhen Li, Xuhong Zhao, Xiaoming Zuo, Zhihai Peng
Pages: 488-494
Published online on: 25 May 2016

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Article Open Access

Investigation of potential molecular biomarkers and small molecule drugs for hepatocellular carcinoma transformed from cirrhosis

Feng Xie, Fang Zhu, Zaiming Lu, Zhengrong Liu, Hongyan Wang
Pages: 495-503
Published online on: 24 May 2016

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Article Open Access

The impact of high co-expression of Sp1 and HIF1α on prognosis of patients with hepatocellular cancer

Liang Liu, Ping Ji, Ning Qu, Wei‑Lin Pu, Dao‑Wen Jiang, Wei‑Yan Liu, Ya‑Qi Li, Rong‑Liang Shi
Pages: 504-512
Published online on: 26 May 2016

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Case Report Open Access

Vaginal implantation metastasis of endometrial carcinoma: A case report

Yueling Wang, Jiang Du, Shulan Lv, Yanxia Sui, Xue Xue, Chao Sun, Junkai Zou, Qunying Ma, Guoxing Fu, Qing Song, Qiling Li
Pages: 513-515
Published online on: 01 June 2016

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Article Open Access

Quercetin reduces cyclin D1 activity and induces G1 phase arrest in HepG2 cells

Jin Zhou, Lu Li, Li Fang, Hua Xie, Wenxiu Yao, Xiang Zhou, Zhujuan Xiong, Li Wang, Zhixi Li, Feng Luo
Pages: 516-522
Published online on: 27 May 2016

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Article Open Access

Increased autophagic response in a population of metastatic breast cancer cells

Yi Li, Emily Falk Libby, Monica J. Lewis, Jianzhong Liu, John J. Shacka, Douglas R. Hurst
Pages: 523-529
Published online on: 24 May 2016

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Article Open Access

Characteristics of bladder transitional cell carcinoma with E‑cadherin and N‑cadherin double‑negative expression

Yang Luo, Yong‑Tong Zhu, Li‑Li Ma, Shi‑Yu Pang, Li‑Jie Wei, Cheng‑Yong Lei, Cheng‑Wu He, Wan‑Long Tan
Pages: 530-536
Published online on: 01 June 2016

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Article Open Access

Identification of disease-associated pathways in pancreatic cancer by integrating genome-wide association study and gene expression data

Jin Long, Zhe Liu, Xingda Wu, Yuanhong Xu, Chunlin Ge
Pages: 537-543
Published online on: 26 May 2016

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Article Open Access

Long noncoding RNA are aberrantly expressed in human papillary thyroid carcinoma

Meiliu Yang, Jinli Tian, Xin Guo, Ying Yang, Ruhua Guan, Mingyue Qiu, Yukai Li, Xueling Sun, Yanfeng Zhen, Yazhong Zhang, Chunyou Chen, Yanbing Li, Hui Fang
Pages: 544-552
Published online on: 01 June 2016

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Case Report Open Access

Thyroid adenoma and nasopharyngeal carcinoma with metastasis to cervical lymph nodes is misdiagnosed and treated for thyroid carcinoma: A case report

Miao Zhang, Heng Wang, Xuefeng Pan, Wenbin Wu, Hui Zhang
Pages: 553-555
Published online on: 20 May 2016

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Article Open Access

CD73 as a novel marker for poor prognosis of oral squamous cell carcinoma

Zhen‑Hu Ren, Yong‑Xiang Yuan, Tong Ji, Chen‑Ping Zhang
Pages: 556-562
Published online on: 01 June 2016

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Article

Fentanyl inhibits the progression of human gastric carcinoma MGC-803 cells by modulating NF-κB-dependent gene expression in vivo

Guodong He, Li Li, Enjian Guan, Jing Chen, Yi Qin, Yubo Xie
Pages: 563-571
Published online on: 25 May 2016

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Article

O‑GlcNAcylation enhances anaplastic thyroid carcinoma malignancy

Yu Cheng, Honglun Li, Jianlin Li, Jisheng Li, Yan Gao, Baodong Liu
Pages: 572-578
Published online on: 30 May 2016

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Article

Therapeutic evaluation of sorafenib for hepatocellular carcinoma using contrast‑enhanced ultrasonography: Preliminary result

Kazue Shiozawa, Manabu Watanabe, Takashi Ikehara, Michio Kogame, Yoshinori Kikuchi, Yoshinori Igarashi, Yasukiyo Sumino
Pages: 579-584
Published online on: 01 June 2016

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Case Report

Isolated double adrenocorticotropic hormone-secreting pituitary adenomas: A case report and review of the literature

Jiujun Pu, Zhiming Wang, Hui Zhou, Ailing Zhong, Kai Jin, Lunliang Ruan, Gang Yang
Pages: 585-590
Published online on: 01 June 2016

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Article

Evaluation of D‑dimer and lactate dehydrogenase plasma levels in patients with relapsed acute leukemia

Wangqiang Hu, Xiaoxia Wang, Rongrong Yang
Pages: 591-596
Published online on: 01 June 2016

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Case Report

Misdiagnosis of an α‑fetoprotein‑producing esophageal carcinoma: A case report and literature review

Ningbo Sun, Xunlu Yin, Yuren Zhong, Xiaotian Zhang, Yan Xie, Xiangfang Meng, Qi Zang
Pages: 597-600
Published online on: 01 June 2016

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Article

Shift in prevalence of HPV types in cervical cytology specimens in the era of HPV vaccination

Sonja Fischer, Marcus Bettstetter, Andrea Becher, Marlene Lessel, Cyril Bank, Matthias Krams, Ingrid Becker, Arndt Hartmann, Wolfgang Jagla, Andreas Gaumann
Pages: 601-610
Published online on: 01 June 2016

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Case Report

Long-term remission of subcutaneous panniculitis-like T-cell lymphoma with central nervous system involvement: A case report

Yajuan Qiu, Dandan Zhang, Mingzhi Zhang
Pages: 611-614
Published online on: 26 May 2016

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Article

Protein expression of nucleophosmin, annexin A3 and nm23-H1 correlates with human nasopharyngeal carcinoma radioresistance in vivo

Song Qu, Xiao‑Yu Li, Zhong‑Guo Liang, Ling Li, Shi‑Ting Huang, Jia‑Quan Li, Dan‑Rong Li, Xiao‑Dong Zhu
Pages: 615-620
Published online on: 26 May 2016

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Article

Molecular pathways associated with transcriptional alterations in hyperparathyroidism

Fang Lee, Jie‑Jen Lee, Woan‑Ching Jan, Chih‑Jen Wu, Han‑Hsiang Chen, Shih‑Ping Cheng
Pages: 621-626
Published online on: 25 May 2016

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Case Report

Chest wall hernia induced by high intensity focused ultrasound treatment of unresectable massive hepatocellular carcinoma: A case report

Qi‑Wen Chen, Wen‑Jing Teng, Qian Chen
Pages: 627-630
Published online on: 25 May 2016

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Article

Decreased expression of TLR7 in gastric cancer tissues and the effects of TLR7 activation on gastric cancer cells

Jiong Jiang, Lei Dong, Bin Qin, Haitao Shi, Xiaoyan Guo, Yan Wang
Pages: 631-636
Published online on: 24 May 2016

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Case Report

Neurofibromatosis type 1 associated with pheochromocytoma and gastrointestinal stromal tumors: A case report and literature review

Dongfeng Pan, Peifeng Liang, Hongyan Xiao
Pages: 637-643
Published online on: 01 June 2016

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Article

Bone mesenchymal stem cells differentiate into myofibroblasts in the tumor microenvironment

Jing Zhang, Dingqi Sun, Qiang Fu, Qingwei Cao, Hui Zhang, Keqin Zhang
Pages: 644-650
Published online on: 30 May 2016

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Article

Fibulin-5 localisation in human endometrial cancer shifts from epithelial to stromal with increasing tumour grade, and silencing promotes endometrial epithelial cancer cell proliferation

Amy Louise Winship, Kate Rainczuk, Amanda Ton, Eva Dimitriadis
Pages: 651-657
Published online on: 01 June 2016

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Article

Speckle‑type POZ (pox virus and zinc finger protein) protein gene deletion in ovarian cancer: Fluorescence in situ hybridization analysis of a tissue microarray

Xiaoyu Hu, Zhu Yang, Manman Zeng, Yi Liu, Xiaotao Yang, Yanan Li, Xu Li, Qiubo Yu
Pages: 658-662
Published online on: 30 May 2016

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Article

Therapeutic effect of taxanes on metastatic breast cancer of various immunohistochemical subtypes

Ippei Fukada, Kazuhiro Araki, Kokoro Kobayashi, Takayuki Kobayashi, Rie Horii, Futoshi Akiyama, Shunji Takahashi, Takuji Iwase, Yoshinori Ito
Pages: 663-669
Published online on: 25 May 2016

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Article

Hypermethylation reduces the expression of PNPLA7 in hepatocellular carcinoma

Xiaojiao Zhang, Jun Zhang, Rui Wang, Shicheng Guo, Huilu Zhang, Yanyun Ma, Qingmei Liu, Haiyan Chu, Xianghong Xu, Yitong Zhang, Dongqin Yang, Jiucun Wang, Jie Liu
Pages: 670-674
Published online on: 01 June 2016

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Article

Involvement of p38MAPK‑ATF2 signaling pathway in alternariol induced DNA polymerase β expression

Jimin Zhao, Junfen Ma, Jing Lu, Yanan Jiang, Yanyan Zhang, Xiaoyan Zhang, Jun Zhao, Hongyan Yang, Youtian Huang, Mingyao Zhao, Kangdong Liu, Ziming Dong
Pages: 675-679
Published online on: 01 June 2016

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Article

Quantitative measurement of adiposity using CT images to predict the benefit of bevacizumab‑based chemotherapy in epithelial ovarian cancer patients

Yunzhi Wang, Theresa Thai, Kathleen Moore, Kai Ding, Scott Mcmeekin, Hong Liu, Bin Zheng
Pages: 680-686
Published online on: 31 May 2016

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Article

Resistance of papillary thyroid cancer stem cells to chemotherapy

Raffaella Giuffrida, Luana Adamo, Gioacchin Iannolo, Luisa Vicari, Dario Giuffrida, Adriana Eramo, Massimo Gulisano, Lorenzo Memeo, Concetta Conticello
Pages: 687-691
Published online on: 01 June 2016

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Article

Protection of organs at risk during neoadjuvant chemoradiotherapy for gastric cancer based on a comparison between conformal and intensity-modulated radiation therapy

Leszek Hawrylewicz, Wojciech Leszczyński, Agnieszka Namysł‑Kaletka, Iwona Bronclik, Jerzy Wydmański
Pages: 692-698
Published online on: 26 May 2016

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Article

JNK1/2 expression and modulation of STAT3 signaling in oral cancer

Ioannis Gkouveris, Nikolaos Nikitakis, Maria Karanikou, George Rassidakis, Alexandra Sklavounou
Pages: 699-706
Published online on: 24 May 2016

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Article

Efficacy of RetroNectin-activated cytokine-induced killer cell therapy in the treatment of advanced hepatocelluar carcinoma

Wei Li, Yaomei Wang, Daniel B. Kellner, Lingdi Zhao, Linping Xu, Quanli Gao
Pages: 707-714
Published online on: 25 May 2016

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Article

miR-137 inhibits renal cell carcinoma growth in vitro and in vivo

Hongxia Zhang, Hongjun Li
Pages: 715-720
Published online on: 24 May 2016

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Article

Association between the p73 gene G4C14‑to‑A4T14 single nucleotide polymorphism and risk of cervical cancer by high resolution melting and PCR with confronting two-pair primers in a Chinese population

Haiyan Guo, Shaodi Yang, Lijian Xu, Ding Li, Jianxin Tang, Shuangshaung Wang, Benjie Wei, Zhengchun Liu
Pages: 721-726
Published online on: 01 June 2016

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Article

Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2

Andrés J. Muñoz Martín, Pilar García Alfonso, Ana B. Rupérez, Miguel Martín Jiménez
Pages: 727-730
Published online on: 01 June 2016

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Article

Isolated brain metastasis as a late recurrence of completely resected non-small cell lung cancer

Lixia Ju , Mingquan Han
Pages: 731-733
Published online on: 01 June 2016

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Article

Incidental and non‑incidental thyroid microcarcinoma

Krzysztof Kaliszewski, Beata Wojtczak, Marta Strutyńska‑Karpińska, Tadeusz Łukieńczuk, Zdzisław Forkasiewicz, Paweł Domosławski
Pages: 734-740
Published online on: 30 May 2016

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Article

miR-299-5p promotes cell growth and regulates G1/S transition by targeting p21Cip1/Waf1 in acute promyelocytic leukemia

Shun‑Quan Wu, Lang‑Hui Zhang, Hao‑Bo Huang, Ya‑Ping Li, Wen‑Yan Niu, Rong Zhan
Pages: 741-747
Published online on: 25 May 2016

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Article

Methylation status of the APC and RASSF1A promoter in cell‑free circulating DNA and its prognostic role in patients with colorectal cancer

Dimitrios Matthaios, Ioanna Balgkouranidou, Anastasios Karayiannakis, Helen Bolanaki, Nikolaos Xenidis, Kyriakos Amarantidis, Leonidas Chelis, Konstantinos Romanidis, Aikaterini Chatzaki, Evi Lianidou, Grigorios Trypsianis, Stylianos Kakolyris
Pages: 748-756
Published online on: 01 June 2016

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Article

Use of negative pressure wound therapy as an adjunct to the treatment of extremity soft-tissue sarcoma with ulceration or impending ulceration

Yu Chen, Song‑Feng Xu, Ming Xu, Xiu‑Chun Yu
Pages: 757-763
Published online on: 01 June 2016

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Article

Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast‑conserving surgery: Factors weighing for and against performing the operation

Alessandro Fancellu
Pages: 764-766
Published online on: 30 May 2016

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Article

Snail levels control the migration mechanism of mesenchymal tumor cells

Cristina Belgiovine, Giulio Chiesa, Ilaria Chiodi, Roberta Frapolli, Katiuscia Bonezzi, Giulia Taraboletti, Maurizio D'incalci, Chiara Mondello
Pages: 767-771
Published online on: 30 May 2016

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

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Article Open Access

Efficacy and safety of rituximab in the treatment of primary central nervous system lymphoma: A meta‑analysis and systematic review of 1,388 patients

Lichaoyue Sun, Wenshu Li, Wei Chen, Chunxing Li, Zhao Ren, Qing Xie, Dongxiao Wang
Article Number: 488
Published online on: 02 September 2026

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Review Open Access

Psychological stress and tumor progression: Molecular mechanisms and therapeutic implications (Review)

Yifei Zhang, Yajun Kong, Shuanbao Zhao
Article Number: 487
Published online on: 02 September 2026

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Article Open Access

Development and evaluation of clinical models based on ultrasound, serum CA153 and molecular subtype in predicting the efficacy of neoadjuvant chemotherapy in breast cancer

Ming-Yue Du, Shu-E Zeng
Article Number: 486
Published online on: 02 September 2026

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Article Open Access

Clinical utility of circulating tumor‑derived endothelial cells in lung cancer detection and prognosis prediction

Xiang Li, Jun Yang, Bin Chen, Ziyu Zhang, Jiangman Zhao, Mengxin Zhao, Zhimou Wang
Article Number: 485
Published online on: 02 September 2026

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Article Open Access

Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix‑associated genes

Liangqian Tu, Yiyin Qiu, Handan Zheng, Bixin Fang, Ming Chen
Article Number: 484
Published online on: 02 September 2026

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Special Issue

Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)

Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun
Article Number: 483
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells

Muliang Ding, Jianzhong Hu, Jiangdong Ni, Zhonghui Zheng, Deye Song, Junjie Wang
Article Number: 482
Published online on: 01 September 2026

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Article Open Access

CCT2 defines a highly cisplatin‑resistant and poor‑prognosis subtype of lung adenocarcinoma

Huafang Mao, Chao Su, Xiaoliang Han, Guoxia Wang
Article Number: 481
Published online on: 28 August 2026

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Expression of Concern Open Access

[Expression of Concern] Simvastatin potentiates doxorubicin activity against MCF‑7 breast cancer cells

Benjaporn Buranrat, Wanwisa Suwannaloet, Jarinyaporn Naowaboot
Article Number: 480
Published online on: 27 August 2026

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Article Open Access

Characterization of ZIC5 expression in esophageal squamous cell carcinoma and its association with patient survival

Bo Yang, Baige Wang, Haiquan Deng, Yong Luo, Shenghao Wu, Huaxin Yin, Hongdian Zhang, Yuncheng Zhang, Zhen Zhang
Article Number: 479
Published online on: 26 August 2026

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Review Open Access

Microbiome‑based diagnostic biomarkers in pancreatic ductal adenocarcinoma: Current evidence and translational challenges (Review)

Huiya Jin, Hui Sun, Jing Yang
Article Number: 478
Published online on: 26 August 2026

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Correction Open Access

[Corrigendum] Long non-coding RNA CCAT2 functions as an oncogene in hepatocellular carcinoma, regulating cellular proliferation, migration and apoptosis

Ning Zhou, Zhongzhou Si, Ting Li, Guangshun Chen, Zhongqiang Zhang, Haizhi Qi
Article Number: 477
Published online on: 26 August 2026

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Article Open Access

Efficacy and safety of ICI‑based triple combination therapy for gene‑negative advanced lung adenocarcinoma

Diwei Mo, Huan Chen, Zhihong Zhu, Jinghua Yu, Xia Yang, Yiyu Lu, Keng Wang, Guifeng Xu, Luwen Lei, Xingxi Pan
Article Number: 476
Published online on: 25 August 2026

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Correction Open Access

[Corrigendum] Angiotensin II type 2 receptor‑interacting protein 3a suppresses proliferation, migration and invasion in tongue squamous cell carcinoma via the extracellular signal‑regulated kinase‑Snai2 pathway

Tingting Zhao, Qianting He, Zhonghua Liu, Xueqiang Ding, Xiaofeng Zhou, Anxun Wang
Article Number: 475
Published online on: 24 August 2026

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Article Open Access

Pazopanib treatment for primary cardiovascular sarcoma: A retrospective observational study and literature review

Shintaro Yamanaka, Yoshihiro Yakushijin, Shinji Hasebe, Shoichiro Yamamoto, Tomomi Fujii, Riko Kitazawa, Taketsugu Fujibuchi, Teruki Kidani, Masaki Maruta
Article Number: 474
Published online on: 21 August 2026

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Case Report Open Access

Primary cutaneous angiosarcoma of the scalp initially misdiagnosed as cellulitis in a 95‑year‑old Asian man: A case report

Baopeng Qi, Qianru Li, Yuan Gao, Yuanyu Tang, Yang Yu
Article Number: 473
Published online on: 21 August 2026

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Article Open Access

Colorectal cancer and tumor vaccines (Review)

Jianshuang Ma, Congming Xiang, Dong Xia
Article Number: 472
Published online on: 21 August 2026

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Article Open Access

Pre‑radiotherapy modified prognostic nutritional index predicts acute radiation enteritis in patients with cervical cancer undergoing radiotherapy: A retrospective study

Yani Zou, Rui Huang, Wenqiang Qin, Chunqiu Wu, Wei Zhang
Article Number: 471
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] MicroRNA‑101 suppresses progression of lung cancer through the PTEN/AKT signaling pathway by targeting DNA methyltransferase 3A

Lumin Wang, Jiayi Yao, Hongfei Sun, Kang He, Dongdong Tong, Tusheng Song, Chen Huang
Article Number: 470
Published online on: 20 August 2026

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Article Open Access

Boost delivery in hypofractionated breast cancer radiotherapy: A registry‑based analysis of treatment patterns and survival

Karoline Elisabeth Horry, Dirk Vordermark, Daniel Medenwald, Jörg Andreas Müller
Article Number: 469
Published online on: 18 August 2026

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Article

Effect of perioperative nutritional status, inflammatory response and postoperative chemotherapy on survival after gastrectomy for advanced gastric cancer

Yoshinori Fujiwara, Shunji Endo, Masaharu Higashida, Masaaki Hori, Yoko Endo, Ryoko Makieda, Akihide Fujii, Miyoko Kobayashi, Kazuhiko Yoshimatsu, Tomio Ueno
Article Number: 468
Published online on: 18 August 2026

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Retraction Open Access

[Retracted] miR‑185‑5p targets ROCK2 and inhibits cell migration and invasion of hepatocellular carcinoma

Yuexiang Niu, Gongen Tang
Article Number: 467
Published online on: 17 August 2026

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Article

OLFML2A expression in acute myeloid leukemia, with exploratory findings in acute lymphoblastic leukemia: Prognostic significance and re‑analysis of public single‑cell transcriptomic data

Xuan Lu, Jinlian Li, Xinru Zhao, Wanchuan Zhuang, Xingxing Chai
Article Number: 466
Published online on: 17 August 2026

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Article Open Access

Identifying an appropriate endogenous control for real‑time PCR of microRNAs in colorectal liver metastases: A comparison of 18s rRNA and small nuclear RNA RNU6B

Clemens Franz, Sibylle Hartmann, Alexis Ulrich, Georgios Polychronidis, Christoph Kahlert, Fee Klupp, Mohammed Al‑Saeedi
Article Number: 465
Published online on: 17 August 2026

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Article Open Access

Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single‑center cross‑sectional study

Xue Chen, Jialing Li, Li Tian, Xinshu Li, Jingwen Guo, Liling He, Shulian Mao, Xitang Yang, Hua Guo
Article Number: 464
Published online on: 17 August 2026

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Article Open Access

Flavokawain A inhibits high glucose‑induced malignant progression of lung cancer cells by suppressing PRMT5‑mediated PTEN neddylation and nuclear translocation

Lei Zheng, Juan Li, Chao Song, Leping Shi, Qian Zhou, Yuyao Guan
Article Number: 463
Published online on: 14 August 2026

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Review Open Access

Metabolic heterogeneity and functional diversity of cancer-associated fibroblasts in gastric cancer (Review)

Qilu Fang, Neng Lv, Shuwei Yu, Jia Wang, Wenxiu Xin
Article Number: 462
Published online on: 14 August 2026

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Article Open Access

Preoperative CA125 and metabolic factors associated with high‑risk pathology in endometrial cancer

Yinuo Wang, Yueqi Yan, Wen Sun, Yiting Gao, Bingli Qi, Xia Li, Shouze Liu, Shikai Liu
Article Number: 461
Published online on: 14 August 2026

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Article Open Access

EGR1 regulates IGF‑1‑stimulated pancreatic cancer cell invasion by increasing IL‑11 expression 

Yena Choi, Euitaek Jung, Junekyu Han, Soon Young Shin
Article Number: 460
Published online on: 13 August 2026

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Review Open Access

Claudin‑18.2: Molecular mechanisms to clinical translation in solid tumors (Review)

Minjie Zhang, Dawei Wu, Yu Tang, Ning Li, Xinhua Yan
Article Number: 459
Published online on: 12 August 2026

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Case Report Open Access

Probable cavernous sinus‑adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang
Article Number: 458
Published online on: 12 August 2026

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Case Report Open Access

Immunotherapy combined with anti‑angiogenic therapy, radiotherapy and chemotherapy for the treatment of giant pelvic osteosarcoma: A case report and literature review

Qingying Yan, Jiewen Yang, Yunxia Liu, Miao Cheng, Zhen Wang, Jialu Chen, Yefeng Xu
Article Number: 457
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Obesity accelerates murine gastric cancer growth by modulating the Sirt1/YAP pathway

Hai-Jun Li, Jun-Ke Fu, Xiang-Ming Che, Lin Fan, Yong Zhang, E Bai
Article Number: 456
Published online on: 12 August 2026

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Article Open Access

Tumor suppressor syntaxin binding protein 1 regulates alternative splicing of DNA repair genes related to radiation sensitivity in breast cancer cells

Meng Zhang, Xiaoxue Zhang, Qian Rou, Ying Liu, Ailifeire Abudujiapaer, Minghui Li, Huaixiong Wang, Fang Cheng
Article Number: 455
Published online on: 12 August 2026

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Retraction Open Access

[Retracted] 2’,4’‑dihydroxychalcone, a flavonoid isolated from Herba oxytropis, suppresses PC‑3 human prostate cancer cell growth by induction of apoptosis 

Yuqing Sheng, Mingchang Zou, Yan Wang, Qiheng Li
Article Number: 454
Published online on: 11 August 2026

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Case Report Open Access

Mixed carcinoma transdifferentiation of bladder urothelial carcinoma after chemotherapy: A case report

Liwei Zhao, Jiaguo Huang, Zhanwen Dong, Ji Sun, Runmiao Hua, Xuliang Wang, Kai Wang
Article Number: 453
Published online on: 10 August 2026

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Case Report Open Access

Primary leiomyosarcoma of the lumbar soft tissue treated with multimodal therapy, including anlotinib: A case report

Jia-Huan Li, De-Xiang Liao, Zhen Hu, Zhi-Yong Zhang, Dan-Dan Ma, Wei-Dong Jin, Tao Fu
Article Number: 452
Published online on: 10 August 2026

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Expression of Concern Open Access

[Expression of Concern] Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Article Number: 451
Published online on: 07 August 2026

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Article Open Access

Prognostic value of the CONUT score in newly diagnosed diffuse large B‑cell lymphoma

Sema Seçilmiş, Hacer Berna Afacan Öztürk, Birgül Ay Karakuş, Asena Dikyar, Kadir Acar, Ahmet Kürşad Güneş
Article Number: 450
Published online on: 06 August 2026

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Article Open Access

DHX15 as a novel immune‑related prognostic biomarker in breast cancer: An integrated bioinformatics analysis with in vitro functional validation

Fan Li, Qin Yue, Jing Li
Article Number: 449
Published online on: 05 August 2026

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Case Report Open Access

Emergence of KRAS mosaicism with multiple variants during treatment with alectinib in ALK‑positive metastatic non‑small cell lung cancer: A case report

Alizée Simon, Gautier Treffel, Guillaume Pax, Guillaume Gauchotte, Marie Husson, Idrissia Hanriot, Agnès Leroux, Jean-Louis Merlin, Alexandre Harlé, Pauline Gilson
Article Number: 448
Published online on: 05 August 2026

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Expression of Concern Open Access

[Expression of Concern] Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation  

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao
Article Number: 447
Published online on: 05 August 2026

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Article

Preliminary study on the efficacy of pazopanib combined with toripalimab as first‑line therapy for metastatic renal cell carcinoma: Real‑world data from a single center

Bin Wang, Tianjun Xing, Hongyu Liu, Xuebing Han, Kai Wu
Article Number: 446
Published online on: 05 August 2026

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Review Open Access

Subtype‑specific mechanisms of lipid metabolism in gynecological malignancies and novel targeted intervention strategies (Review)

Yidan Ran
Article Number: 445
Published online on: 04 August 2026

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Review Open Access

Chrono‑immunotherapy in genitourinary oncology: From emerging evidence to clinical translation (Review)

Osama Zein Deen, Xin Ye, Patsy Lee, Roxana Astani, Georg Bjarnason, Christian Kollmannsberger, Bernhard Eigl, Guliz Ozgun
Article Number: 444
Published online on: 03 August 2026

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Case Report Open Access

Imaging features and clinical management of mesenteric cavernous lymphangioma: A case report and literature review

Zhongze Zhao, Ermin Cai, Tong Zhou, Jianju Feng, Lingzhi Gu
Article Number: 443
Published online on: 03 August 2026

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Article Open Access

Association between the expression of GSTP1 and mutant p53, poor chemotherapy response and metastasis in patients with osteosarcoma

Bangkit Primayudha, Evelina Kodrat, Yogi Prabowo, Aryadi Kurniawan, Nurjati Chairani Siregar, Muhamad Naseh Sajadi Budi Irawan, Rahadyan Magetsari, I Gede Eka Wiratnaya, Istan Irmansyah Irsan, Achmad Fauzi Kamal
Article Number: 442
Published online on: 03 August 2026

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Article Open Access

Astragaloside IV suppresses triple‑negative breast cancer cell migration and invasion by targeting BCAT1‑mediated branched‑chain amino acid metabolism

Yi-Ting Liu, Lu Zhang, Xiao-Dong Sun
Article Number: 441
Published online on: 03 August 2026

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Article Open Access

LC‑MS/MS‑based clinical value exploration of the methionine cycle in luminal breast cancer

Wenxuan Wu, Yifeng Tu, Han Yao, Yajun Mao, Changfei Mao, Feifei Xu, Zhongcheng Wang
Article Number: 440
Published online on: 03 August 2026

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Article

Accuracy of percutaneous ultrasound‑guided needle biopsy of abdominal lymph nodes for the diagnosis of malignant disease

Camilla Mazzoni, Lisa Argnani, Davide Di Benedetto, Sofia Maria Bakken, Beatrice Casadei, Cinzia Pellegrini, Leonardo De Marco, Marta Machado, Alessandro Broccoli, Pier Luigi Zinzani, Carla Serra
Article Number: 439
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Esomeprazole affects the proliferation, metastasis, apoptosis and chemosensitivity of gastric cancer cells by regulating lncRNA/circRNA‑miRNA‑mRNA ceRNA networks

Qian Xu, Xiyun Jia, Qian Wu, Lei Shi, Zihan Ma, Nan Ba, Han Zhao, Xingzhou Xia, Zisen Zhang
Article Number: 438
Published online on: 03 August 2026

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Case Report Open Access

Papillary thyroid carcinoma in a patient with long‑standing chronic lymphocytic leukemia: A case report

Jiaxiang Ma, Tieying Gan, Ailin Song, Hongyou Tian, Shaoce Xu, Lei Zhao
Article Number: 437
Published online on: 30 July 2026

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Review Open Access

Current status and targeted therapies in endometrial cancer: Molecular classification‑driven treatment strategies (Review)

Xinyu Li, Jie Liu, Fang Huang, Xinyue Deng, Mingxuan Chen, Wen Mou, Wenxia Liu
Article Number: 436
Published online on: 30 July 2026

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Article Open Access

Role of lipid‑associated fibroblasts and their signature genes FABP4, CD36 and ABCA8 in gastric cancer progression

Junqun Liao, Lin Wu, Li Zhou, Qiao Ling, Piyun Zhang
Article Number: 435
Published online on: 30 July 2026

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Correction Open Access

[Corrigendum] Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 434
Published online on: 30 July 2026

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Article

Influence of the second primary cancer on clinical outcomes of nasopharyngeal carcinoma following definitive chemoradiotherapy

Shu-Chin Yang, Chung-Han Ho, Li-Tsun Shieh, Sung-Wei Lee, Chia-Chun Chen, Sheng-Yow Ho
Article Number: 433
Published online on: 29 July 2026

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Review Open Access

ETS transcription factor ELK3: Molecular insights and translational horizons in cancer (Review)

Zhenzhe Liu, Zhong Wei, Zhensheng Li, Liqiang Zhou
Article Number: 432
Published online on: 29 July 2026

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Review Open Access

Bone niche‑driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

Bolin Tang, Yuhuai Wu, Jianping Liu, Rui Pan
Article Number: 431
Published online on: 29 July 2026

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Article Open Access

Deep learning model based on CT images to predict Ki‑67 expression in renal carcinoma

Dan Shen, Hongmei Li, Bingye Shi, Tao Ma, Bin Zhou, Chao Gao, Yibo Liu, Zhenyu Cui
Article Number: 430
Published online on: 29 July 2026

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Retraction Open Access

[Retracted] Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 429
Published online on: 29 July 2026

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Article Open Access

Investigation of CRP and NLR as potential biomarkers for redefining biological borderline resectable pancreatic cancer

Keishi Kawasaki, Hidehiro Tajima, Teppei Tatsuoka, Musashi Takada, Soya Meguro, Hirotaka Ishido, Hideyuki Yoshitomi
Article Number: 428
Published online on: 28 July 2026

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Article Open Access

FAM122B acts as an independent poor prognostic factor and promotes the malignant biological behaviors of low‑grade glioma

Hao Wang, Tengfei Guo, Yanbo Gao, Yi Zhou, Rongjun Qian
Article Number: 427
Published online on: 28 July 2026

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Article Open Access

A nomogram based on immunohistochemistry and lymphocyte‑to‑monocyte ratio for predicting risk stratification in endometrial carcinoma

Yunyun Chen, Jianwei Li, Li Yan, Peili Liu, Fanfei Meng, Yajun Zhang
Article Number: 426
Published online on: 28 July 2026

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Correction Open Access

[Corrigendum] Effects of Platycodin D on apoptosis, migration, invasion and cell cycle arrest of gallbladder cancer cells

Xiaoyu Zhang, Tianyu Zhai, Zhenyu Hei, Di Zhou, Longyang Jin, Chao Han, Jiandong Wang
Article Number: 425
Published online on: 27 July 2026

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Case Report Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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November-2026 Volume 32 Issue 5

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characteristics and potential impact of previous treatment history in metachronous contralateral breast cancer: Insights from a real‑world retrospective study

Ritsuko Sasaki, Koji Yamamoto, Kotaro Iijima, Masami Arai, Mitsue Saito, Goro Kutomi
Article Number: 492
Published online on: 04 September 2026

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Article Open Access

Transcriptional activation of GSTP1 by ANXA3 is associated with cisplatin sensitivity in colorectal cancer cells

Ximao Cui, Xin Xu, Xiao Yuan, Kunkun Han, Han Wang, Shun Zhang, Chiye Ma, Renhao Hu, Xiaohua Jiang, Yili Yang
Article Number: 491
Published online on: 04 September 2026

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Case Report Open Access

Seven‑year follow‑up demonstrating sustained survival following 125I seed brachytherapy in an elderly patient with lip squamous cell carcinoma and Alzheimer's disease: A case report

Guangsheng Zhao, Xinyu Zhou, Shunhang Yin, Fang Xu, Licai Xu, Qiushi Wang, Jun Zhou, Song Liu
Article Number: 490
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Effects and mechanisms of blocking the hedgehog signaling pathway in human gastric cancer cells

Hongbing Gu, Xu Li, Congzhi Zhou, Yugang Wen, Yang Shen, Lisheng Zhou, Jikun Li
Article Number: 489
Published online on: 03 September 2026

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