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July-2016 Volume 12 Issue 1

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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Article

Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2

  • Authors:
    • Andrés J. Muñoz Martín
    • Pilar García Alfonso
    • Ana B. Rupérez
    • Miguel Martín Jiménez
  • View Affiliations / Copyright

    Affiliations: Medical Oncology Service, Hospital General Universitario Gregorio Marañón, Madrid 28007, Spain
  • Pages: 727-730
    |
    Published online on: June 1, 2016
       https://doi.org/10.3892/ol.2016.4667
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Abstract

Metastatic pancreatic cancer (PC) has been associated with a considerably poor prognosis. Due to its toxicity, first‑line combination chemotherapy is limited to patients with a good performance status (PS). Previously nab‑paclitaxel plus gemcitabine has been demonstrated to improve the overall survival rate in patients with advanced pancreatic cancer with a good PS. The present study reports a case of a patient with metastatic PC with a poor PS (Eastern Cooperative Oncology Group 2) and a complex set of comorbidities treated with nab‑paclitaxel plus gemcitabine as a first‑line palliative therapy. Adjusted doses of nab‑paclitaxel plus gemcitabine reached a favourable clinical, radiological and biochemical response in the present patient, which increased the quality of life for the patient. Eventually, the patient succumbed to acute cholangitis. Based on the results of the present study, nab‑paclitaxel plus gemcitabine appears to be a favourable treatment as first‑line palliative chemotherapy for patients with metastatic PC, comorbidities and poor PS.
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Copy and paste a formatted citation
Spandidos Publications style
Muñoz Martín AJ, García Alfonso P, Rupérez AB and Martín Jiménez M: Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2. Oncol Lett 12: 727-730, 2016.
APA
Muñoz Martín, A.J., García Alfonso, P., Rupérez, A.B., & Martín Jiménez, M. (2016). Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2. Oncology Letters, 12, 727-730. https://doi.org/10.3892/ol.2016.4667
MLA
Muñoz Martín, A. J., García Alfonso, P., Rupérez, A. B., Martín Jiménez, M."Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2". Oncology Letters 12.1 (2016): 727-730.
Chicago
Muñoz Martín, A. J., García Alfonso, P., Rupérez, A. B., Martín Jiménez, M."Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2". Oncology Letters 12, no. 1 (2016): 727-730. https://doi.org/10.3892/ol.2016.4667
Copy and paste a formatted citation
x
Spandidos Publications style
Muñoz Martín AJ, García Alfonso P, Rupérez AB and Martín Jiménez M: Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2. Oncol Lett 12: 727-730, 2016.
APA
Muñoz Martín, A.J., García Alfonso, P., Rupérez, A.B., & Martín Jiménez, M. (2016). Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2. Oncology Letters, 12, 727-730. https://doi.org/10.3892/ol.2016.4667
MLA
Muñoz Martín, A. J., García Alfonso, P., Rupérez, A. B., Martín Jiménez, M."Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2". Oncology Letters 12.1 (2016): 727-730.
Chicago
Muñoz Martín, A. J., García Alfonso, P., Rupérez, A. B., Martín Jiménez, M."Nab‑paclitaxel plus gemcitabine as first‑line palliative chemotherapy in a patient with metastatic pancreatic cancer with Eastern Cooperative Oncology Group performance status of 2". Oncology Letters 12, no. 1 (2016): 727-730. https://doi.org/10.3892/ol.2016.4667
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