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Case Report Open Access

Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review

  • Authors:
    • Tian‑Bao Wang
    • Bao‑Guang Hu
    • Da‑Wei Liu
    • Zhen‑Hua Gao
    • Han‑Ping Shi
    • Wen‑Guang Dong
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, The First Affiliated Hospital, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Gastrointestinal Surgery, The Affiliated Hospital, Binzhou Medical College, Binzhou, Shandong 256603, P.R. China, Department of Pathology, The First Affiliated Hospital, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Radiology, The First Affiliated Hospital, Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 928-932
    |
    Published online on: June 15, 2016
       https://doi.org/10.3892/ol.2016.4720
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Abstract

Sclerosing angiomatoid nodular transformation (SANT) is a rare benign splenic vascular lesion. Since it was first defined in 2004, a total of 132 cases of SANT have been reported in ~50 studies in the English literature. However, it remains difficult to form a definitive pre‑operative differential diagnosis of SANT compared with other splenic tumors or malignant lesions. The present study reports a pathologically proven case of SANT in a 29‑year‑old man who initially presented with left upper quadrant and back discomfort. The study also provides a review of the current knowledge on the condition, including the clinical profile, imaging features, cytological features, differential diagnosis and treatment of SANT. The most important distinguishing features of SANT are its typical vascular character and lack of other features that are typical of a granuloma. A splenectomy is required and the diagnosis is based on pathological analysis.
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Copy and paste a formatted citation
Spandidos Publications style
Wang TB, Hu BG, Liu DW, Gao ZH, Shi HP and Dong WG: Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review. Oncol Lett 12: 928-932, 2016.
APA
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., & Dong, W. (2016). Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review. Oncology Letters, 12, 928-932. https://doi.org/10.3892/ol.2016.4720
MLA
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., Dong, W."Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review". Oncology Letters 12.2 (2016): 928-932.
Chicago
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., Dong, W."Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review". Oncology Letters 12, no. 2 (2016): 928-932. https://doi.org/10.3892/ol.2016.4720
Copy and paste a formatted citation
x
Spandidos Publications style
Wang TB, Hu BG, Liu DW, Gao ZH, Shi HP and Dong WG: Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review. Oncol Lett 12: 928-932, 2016.
APA
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., & Dong, W. (2016). Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review. Oncology Letters, 12, 928-932. https://doi.org/10.3892/ol.2016.4720
MLA
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., Dong, W."Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review". Oncology Letters 12.2 (2016): 928-932.
Chicago
Wang, T., Hu, B., Liu, D., Gao, Z., Shi, H., Dong, W."Sclerosing angiomatoid nodular transformation of the spleen: A case report and literature review". Oncology Letters 12, no. 2 (2016): 928-932. https://doi.org/10.3892/ol.2016.4720
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